Acute Migraine Therapeutics

1. Axert patent expiration

Treatment: Treatment of migraine

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US5565447

(Pediatric)

JANSSEN PHARMS Indole derivatives
Nov, 2015

(10 years ago)

US5565447 JANSSEN PHARMS Indole derivatives
May, 2015

(10 years ago)




Drugs and Companies using ALMOTRIPTAN MALATE ingredient

Market Authorisation Date: 07 May, 2001

Dosage: TABLET

How can I launch a generic of AXERT before it's drug patent expiration?
More Information on Dosage

AXERT family patents

Family Patents

2. Frova patent expiration

Treatment: Acute treatment of migraine attacks with or without aura in adults

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US5464864 ENDO OPERATIONS Use of tetrahydrocarbazone derivatives as 5HT1 receptor agonists
Nov, 2015

(10 years ago)

US5616603 ENDO OPERATIONS Enantiomers of carbazole derivatives as 5-HT1 -like agonists
Apr, 2014

(11 years ago)

US5637611 ENDO OPERATIONS Medicaments
Jun, 2014

(11 years ago)

US5827871 ENDO OPERATIONS Medicaments 1,2,3,4-tetrahydrocarbazoles and 5-HT1 agonist use thereof
Oct, 2015

(10 years ago)

US5962501 ENDO OPERATIONS Enantiomer of carbazole derivative as 5-HT1-like agonists
Dec, 2013

(12 years ago)




Drugs and Companies using FROVATRIPTAN SUCCINATE ingredient

Market Authorisation Date: 08 November, 2001

Dosage: TABLET

How can I launch a generic of FROVA before it's drug patent expiration?
More Information on Dosage

FROVA family patents

Family Patents

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3. Nurtec Odt patent expiration

Treatment: Preventive treatment of episodic migraine in adults

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents protects the active chemical substance. Only drug patent owner can launch products that use this active substance.
US8314117 PFIZER CGRP receptor antagonists
Feb, 2034

(8 years from now)

US8759372 PFIZER N-(5S,6S,9R)-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-ctclohepta[b]Pyridin-9-yl-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-carboxylate salt
Feb, 2033

(7 years from now)

These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US11083724 PFIZER Rimegepant for CGRP related disorders
Mar, 2039

(13 years from now)




Drug Exclusivity Drug Exclusivity Expiration
New Indication(I-865) May 27, 2024
New Chemical Entity Exclusivity(NCE) Feb 27, 2025

Drugs and Companies using RIMEGEPANT SULFATE ingredient

NCE-1 date: 28 February, 2024

Market Authorisation Date: 27 February, 2020

Dosage: TABLET, ORALLY DISINTEGRATING

More Information on Dosage

NURTEC ODT family patents

Family Patents

4. Relpax patent expiration

Treatment: Treatment of migraine with or without aura

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US5545644 UPJOHN Indole derivatives
Dec, 2016

(9 years ago)

US6110940 UPJOHN Salts of an anti-migraine indole derivative
Aug, 2017

(8 years ago)




Drugs and Companies using ELETRIPTAN HYDROBROMIDE ingredient

Market Authorisation Date: 26 December, 2002

Dosage: TABLET

How can I launch a generic of RELPAX before it's drug patent expiration?
More Information on Dosage

RELPAX family patents

Family Patents

5. Reyvow patent expiration

Treatment: Acute treatment of migraine; Acute treatment of migraine with or without aura in adults

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents protects the active chemical substance. Only drug patent owner can launch products that use this active substance.
US7423050 ELI LILLY AND CO Pyridinoylpiperidines as 5-HT1F agonists
Feb, 2028

(2 years from now)

US11053214 ELI LILLY AND CO Compositions and methods related to pyridinoylpiperidine 5-HT1F agonists
Dec, 2037

(11 years from now)

These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US8748459 ELI LILLY AND CO Pyridinoylpiperidines as 5-HT1F agonists
Mar, 2023

(2 years ago)

US12257246 ELI LILLY AND CO Composition of 2,4,6-trifluoro-n-[6-(1-methyl-piperidin-4-carbonyl)-pyridin-2-yl[-benzamide
Jul, 2030

(4 years from now)

US12071423 ELI LILLY AND CO Processes and intermediate for the large-scale preparation of 2,4,6-trifluoro-N-[6-(1-methyl-piperidine-4-carbonyl)-pyridin-2-yl]-benzamide hemisuccinate, and preparation of 2,4,6-trifluoro-N-[6-(1-methyl-piperidine-4-carbonyl)-pyridin-2-yl]-benzamide acetate
Jul, 2040

(14 years from now)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Jan 31, 2025

Drugs and Companies using LASMIDITAN SUCCINATE ingredient

NCE-1 date: 01 February, 2024

Market Authorisation Date: 31 January, 2020

Dosage: TABLET

More Information on Dosage

REYVOW family patents

Family Patents

6. Ubrelvy patent expiration

Treatment: Acute treatment of migraine with or without aura in a patient with severe hepatic impairment; Acute treatment of migraine with or without aura in adults; Acute treatment of migraine with or without au...

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents protects the active chemical substance. Only drug patent owner can launch products that use this active substance.
US9499545 ABBVIE Piperidinone carboxamide azaindane CGRP receptor antagonists
Nov, 2031

(5 years from now)

US8754096 ABBVIE Piperidinone carboxamide azaindane CGRP receptor antagonists
Jul, 2032

(6 years from now)

US8912210 ABBVIE Piperidinone carboxamide azaindane CGRP receptor antagonists
Dec, 2033

(7 years from now)

These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US11717515 ABBVIE Treatment of migraine
Dec, 2041

(15 years from now)

US9833448 ABBVIE Piperidinone carboxamide azaindane CGRP receptor antagonists
Nov, 2031

(5 years from now)

US12329750 ABBVIE NA
Dec, 2041

(15 years from now)

US12194030 ABBVIE Treatment of migraine
Dec, 2041

(15 years from now)

US12220408 ABBVIE Treatment of migraine
Jan, 2035

(9 years from now)

US12070450 ABBVIE Treatment of migraine
Dec, 2041

(15 years from now)

US11857542 ABBVIE Treatment of migraine
Dec, 2041

(15 years from now)

US12458632 ABBVIE NA
Jan, 2035

(9 years from now)

US12168004 ABBVIE Treatment of migraine
Jan, 2035

(9 years from now)

US11925709 ABBVIE Tablet formulation for CGRP active compounds
Jan, 2035

(9 years from now)

US12458633 ABBVIE NA
Jan, 2035

(9 years from now)

US10117836 ABBVIE Tablet formulation for CGRP active compounds
Jan, 2035

(9 years from now)

US12310953 ABBVIE Pharmaceutical formulations for the treatment of migraine
Jan, 2035

(9 years from now)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Dec 23, 2024

Drugs and Companies using UBROGEPANT ingredient

NCE-1 date: 24 December, 2023

Market Authorisation Date: 23 December, 2019

Dosage: TABLET

More Information on Dosage

UBRELVY family patents

Family Patents

7. Zavzpret patent expiration

Treatment: Administration of zavegepant for acute treatment of migraine with or without aura

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents protects the active chemical substance. Only drug patent owner can launch products that use this active substance.
US8481546 PFIZER CGRP receptor antagonist
Oct, 2031

(5 years from now)

US7220862 PFIZER Calcitonin gene related peptide receptor antagonists
Jan, 2024

(1 year, 11 months ago)

These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US7314883 PFIZER Anti-migraine treatments
Dec, 2023

(2 years ago)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Mar 09, 2028

Drugs and Companies using ZAVEGEPANT HYDROCHLORIDE ingredient

NCE-1 date: 10 March, 2027

Market Authorisation Date: 09 March, 2023

Dosage: SPRAY, METERED

More Information on Dosage

ZAVZPRET family patents

Family Patents