Opioid Induced Constipation In Chronic Non Cancer Pain Therapeutics

1. Relistor patent expiration

Treatment: Treatment of opioid-induced constipation

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US6559158 SALIX Use of methylnaltrexone and related compounds to treat chronic opioid use side affects
Nov, 2017

(8 years ago)

US9180125 SALIX Peripheral opioid receptor antagonists and uses thereof
Sep, 2029

(3 years from now)

US9492445 SALIX Peripheral opioid receptor antagonists and uses thereof
Sep, 2029

(3 years from now)

US9724343 SALIX Peripheral opioid receptor antagonists and uses thereof
Sep, 2029

(3 years from now)

US8420663 SALIX Peripheral opioid receptor antagonists and uses thereof
Sep, 2029

(3 years from now)

US8956651 SALIX Oral formulations and lipophilic salts of methylnal trexone
Mar, 2031

(5 years from now)

US9314461 SALIX Oral formulations and lipophilic salts of methylnaltrexone
Mar, 2031

(5 years from now)

US10376505 SALIX Oral formulations and lipophilic salts of methylnaltrexone
Mar, 2031

(5 years from now)

US8524276 SALIX Oral formulations and lipophilic salts of methylnaltrexone
Mar, 2031

(5 years from now)

US10307417 SALIX Oral formulations and lipophilic salts of methylnaltrexone
Mar, 2031

(5 years from now)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Apr 24, 2013
New Product(NP) Jul 19, 2019

Drugs and Companies using METHYLNALTREXONE BROMIDE ingredient

Market Authorisation Date: 19 July, 2016

Dosage: TABLET

How can I launch a generic of RELISTOR before it's drug patent expiration?
More Information on Dosage

RELISTOR family patents

Family Patents

2. Relistor patent expiration

Treatment: Treatment of opioid-induced constipation; Treatment of opioid-induced constipation (oic) in adults with chronic non-cancer pain, including patients with chronic pain related to prior cancer or its tre...

RELISTOR's oppositions filed in EPO
Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US8420663 SALIX PHARMS Peripheral opioid receptor antagonists and uses thereof
Sep, 2029

(3 years from now)

US6559158 SALIX PHARMS Use of methylnaltrexone and related compounds to treat chronic opioid use side affects
Nov, 2017

(8 years ago)

US8822490 SALIX PHARMS Peripheral opioid receptor antagonists and uses thereof
Sep, 2029

(3 years from now)

US10376584 SALIX PHARMS Stable pharmaceutical formulations of methylnaltrexone
Apr, 2024

(1 year, 9 months ago)

US12303592 SALIX PHARMS Formulations for parenteral delivery of compounds and uses thereof
Aug, 2027

(1 year, 6 months from now)

US8247425 SALIX PHARMS Peripheral opioid receptor antagonists and uses thereof
Dec, 2030

(4 years from now)

US9492445 SALIX PHARMS Peripheral opioid receptor antagonists and uses thereof
Sep, 2029

(3 years from now)

US8552025 SALIX PHARMS Stable methylnaltrexone preparation
Apr, 2024

(1 year, 9 months ago)

US9669096 SALIX PHARMS Stable pharmaceutical formulations of methylnaltrexone
Apr, 2024

(1 year, 9 months ago)

US9180125 SALIX PHARMS Peripheral opioid receptor antagonists and uses thereof
Sep, 2029

(3 years from now)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Apr 24, 2013
New Product(NP) Jul 19, 2019

Drugs and Companies using METHYLNALTREXONE BROMIDE ingredient

NCE-1 date: 24 April, 2012

Market Authorisation Date: 27 September, 2010

Dosage: SOLUTION

How can I launch a generic of RELISTOR before it's drug patent expiration?
More Information on Dosage

RELISTOR family patents

Family Patents

Stay ahead of others in designing the generic launch strategy of these 5 blockbuster drugs expiring in next 5 years.

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3. Symproic patent expiration

Treatment: Treatment of opioid-induced constipation

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents protects the active chemical substance. Only drug patent owner can launch products that use this active substance.
US8536192 BDSI 6,7-unsaturated-7-carbamoyl substituted morphinan derivative
Oct, 2026

(8 months from now)

US8084460 BDSI 6,7-unsaturated-7-carbamoyl substituted morphinan derivative
Jan, 2028

(2 years from now)

USRE46375 BDSI 6,7-unsaturated-7-carbamoyl substituted morphinan derivative
Oct, 2026

(8 months from now)

USRE46365 BDSI 6,7-unsaturated-7-carbamoyl substituted morphinan derivative
Feb, 2031

(5 years from now)

US9108975 BDSI Crystal of 6,7-unsaturated-7-carbamoyl morphinan derivative and method for producing the same
Nov, 2031

(5 years from now)

US10952968 BDSI Preparation containing 6,7-unsaturated-7-carbamoyl morphinan derivatives
May, 2033

(7 years from now)

These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US12350377 BDSI NA
May, 2033

(7 years from now)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Mar 23, 2022

Drugs and Companies using NALDEMEDINE TOSYLATE ingredient

NCE-1 date: 23 March, 2021

Market Authorisation Date: 23 March, 2017

Dosage: TABLET

More Information on Dosage

SYMPROIC family patents

Family Patents