Naldemedine Tosylate Patent Expiration

Naldemedine Tosylate is Used for treating opioid-induced constipation. It was first introduced by Biodelivery Sciences International Inc in its drug Symproic on Mar 23, 2017.


Naldemedine Tosylate Patents

Given below is the list of patents protecting Naldemedine Tosylate, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Symproic US10952968 Preparation containing 6,7-unsaturated-7-carbamoyl morphinan derivatives May 13, 2033 Bdsi
Symproic US8084460 6,7-unsaturated-7-carbamoyl substituted morphinan derivative Jan 11, 2028 Bdsi
Symproic US8536192 6,7-unsaturated-7-carbamoyl substituted morphinan derivative Oct 05, 2026 Bdsi
Symproic US9108975 Crystal of 6,7-unsaturated-7-carbamoyl morphinan derivative and method for producing the same Nov 11, 2031 Bdsi
Symproic USRE46365 6,7-unsaturated-7-carbamoyl substituted morphinan derivative Jan 11, 2028 Bdsi
Symproic USRE46375 6,7-unsaturated-7-carbamoyl substituted morphinan derivative Oct 05, 2026 Bdsi


A patent's expiry date may change depending upon legal activities going on that patent. Critical activities like abandoning of a patent, term extension of a patent or amendment of its claims can increase or decrease the life of a patent hence affecting its expiry date and in turn affecting the generic launch date of that drug. Tracking these ongoing activities on a patent application helps to keep an eye on the latest developments in the patent process of the drug which can give an idea of how early a drug's generic could be available. The next section provides a list of recent legal activities on Naldemedine Tosylate's patents.

Given below is the list recent legal activities going on the following patents of Naldemedine Tosylate.

Event Date Patent/Publication
Patent litigations
Payment of Maintenance Fee, 8th Year, Large Entity 01 Feb, 2023 US9108975
Patent Issue Date Used in PTA Calculation 23 Mar, 2021 US10952968
Recordation of Patent Grant Mailed 23 Mar, 2021 US10952968
Email Notification 05 Mar, 2021 US10952968
Issue Notification Mailed 03 Mar, 2021 US10952968
Email Notification 18 Feb, 2021 US10952968
Mail Response to 312 Amendment (PTO-271) 18 Feb, 2021 US10952968
Printer Rush- No mailing 18 Feb, 2021 US10952968
Dispatch to FDC 17 Feb, 2021 US10952968
Response to Amendment under Rule 312 08 Feb, 2021 US10952968



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