Salix Drug Patent Portfolio

Salix owns 12 orange book drugs protected by 112 US patents with Metozolv Odt having the least patent protection, holding only 1 patent. And Xifaxan with maximum patent protection, holding 35 patents. Given below is the list of Salix's drug patents along with their expiration dates.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US10011637 Ultra-pure agonists of guanylate cyclase C, method of making and using same 05 Jun, 2034
Active
US11142549 Ultra-pure agonists of guanylate cyclase C, method of making and using same 05 Jun, 2034
Active
US11834521 Ultra-pure agonists of guanylate cyclase C, method of making and using same 05 Jun, 2034
Active
US12146003 Ultra-pure agonists of guanylate cyclase C, method of making and using same 05 Jun, 2034
Active
US10016504 Compositions 10 Sep, 2033
Active
US10918723 Colon cleansing compositions and methods of use 10 Sep, 2033
Active
US12083179 Colon cleansing compositions and method of use 10 Sep, 2033
Active
US8999313 Compositions 10 Sep, 2033
Active
US9326969 Compositions 10 Sep, 2033
Active
US9707297 Compositions 10 Sep, 2033
Active
US9616097 Formulations of guanylate cyclase C agonists and methods of use 20 Aug, 2032
Active
US9592252 Colonoscopy—preparation 11 Aug, 2032
Active
US10646512 Colonoscopy - preparation 25 Mar, 2032
Active
US10780112 Colonoscopy-preparation 09 Mar, 2032
Active
US10792306 Colonoscopy—preparation 09 Mar, 2032
Active
US11529368 Colonoscopy—preparation 09 Mar, 2032
Active
US11319346 Ultra-pure agonists of guanylate cyclase C, method of making and using same 01 Mar, 2032
Active
US9610321 Formulations of guanylate cyclase C agonists and methods of use 15 Sep, 2031
Active
US9919024 Formulations of guanylate cyclase C agonists and methods of use 15 Sep, 2031
Active
US9925231 Formulations of guanylate cyclase C agonists and methods of use 15 Sep, 2031
Active
US10307375 Controlled release and taste masking oral pharmaceutical composition 07 Sep, 2031
Active
US10660858 Controlled release and taste masking oral pharmaceutical composition 07 Sep, 2031
Active
US8895064 Controlled release and taste masking oral pharmaceutical composition 07 Sep, 2031
Active
US9132093 Controlled release and taste making oral pharmaceutical composition 07 Sep, 2031
Active
US9192581 Controlled release and taste masking oral pharmaceutical composition 07 Sep, 2031
Active
US10307417 Oral formulations and lipophilic salts of methylnaltrexone 10 Mar, 2031
Active
US10376505 Oral formulations and lipophilic salts of methylnaltrexone 10 Mar, 2031
Active
US8524276 Oral formulations and lipophilic salts of methylnaltrexone 10 Mar, 2031
Active
US8956651 Oral formulations and lipophilic salts of methylnal trexone 10 Mar, 2031
Active
US9314461 Oral formulations and lipophilic salts of methylnaltrexone 10 Mar, 2031
Active
US8247425 Peripheral opioid receptor antagonists and uses thereof 31 Dec, 2030
Active
US8865688 Compositions and methods for treatment of bowel diseases with granulated mesalamine 01 May, 2030
Active
US10314828 Methods of treating hepatic encephalopathy 02 Oct, 2029
Active
US8642573 Methods of treating hepatic encephalopathy 02 Oct, 2029
Active
US8969398 Methods of treating hepatic encephalopathy 02 Oct, 2029
Active
US8420663 Peripheral opioid receptor antagonists and uses thereof 30 Sep, 2029
Active
US8822490 Peripheral opioid receptor antagonists and uses thereof 30 Sep, 2029
Active
US9180125 Peripheral opioid receptor antagonists and uses thereof 30 Sep, 2029
Active
US9492445 Peripheral opioid receptor antagonists and uses thereof 30 Sep, 2029
Active
US9724343 Peripheral opioid receptor antagonists and uses thereof 30 Sep, 2029
Active
US10335397 Methods of treating hepatic encephalopathy 24 Jul, 2029
Active
US10709694 Methods of treating hepatic encephalopathy 24 Jul, 2029
Active
US7928115 Methods of treating travelers diarrhea and hepatic encephalopathy 24 Jul, 2029
Active
US8829017 Methods of treating traveler's diarrhea and hepatic encephalopathy 24 Jul, 2029
Active
US8946252 Methods of treating traveler's diarrhea and hepatic encephalopathy 24 Jul, 2029
Active
US9421195 Methods of treating hepatic encephalopathy 24 Jul, 2029
Active
US9629828 Methods of treating traveler's diarrhea and hepatic encephalopathy 24 Jul, 2029
Active
US8309569 Methods for treating diarrhea-associated irritable bowel syndrome 18 Jul, 2029
Active
US10456384 Methods for treating irritable bowel syndrome (IBS) 26 Feb, 2029
Active
US10765667 Methods for treating irritable bowel syndrome (IBS) 26 Feb, 2029
Active
US11564912 Methods for treating irritable bowel syndrome (IBS) 26 Feb, 2029
Active
US11779571 Methods for treating irritable bowel syndrome (IBS) 26 Feb, 2029
Active
US7687075 Colonic purgative composition with soluble binding agent 22 Jun, 2028
Active
US7041786 Guanylate cyclase receptor agonists for the treatment of tissue inflammation and carcinogenesis 30 Jan, 2028
Active
US8193196 Polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations 02 Sep, 2027
Active
US12303592 Formulations for parenteral delivery of compounds and uses thereof 03 Aug, 2027
Active
US10703763 Polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations 27 Feb, 2026
Active
US8518949 Polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations 27 Feb, 2026
Active
US8741904 Polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations 27 Feb, 2026
Active
US9271968 Polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations 27 Feb, 2026
Active
US7906542 Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin 01 Jun, 2025 Expired
US7915275 Use of polymorphic forms of rifaximin for medical preparations 23 Feb, 2025 Expired
US7658944 Solid dosage form comprising a fibrate 09 Dec, 2024 Expired
US8124125 Solid dosage form comprising a fibrate 01 Oct, 2024 Expired
US8481078 Solid dosage form comprising a fibrate 01 Oct, 2024 Expired
US9173847 Tablet comprising a fibrate 01 Oct, 2024 Expired
US7169381 Colon cleansing compositions and methods 01 Sep, 2024 Expired
US7658914 Colon cleansing compositions 01 Sep, 2024 Expired
US7045620 Polymorphous forms of rifaximin, processes for their production and use thereof in medicinal preparations 19 Jun, 2024 Expired
US7612199 Polymorphic forms α, β, and γ of rifaximin 19 Jun, 2024 Expired
US7902206 Polymorphic forms α, β and γ of rifaximin 19 Jun, 2024 Expired
US8158644 Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin 19 Jun, 2024 Expired
US8158781 Polymorphic forms α, β and γ of rifaximin 19 Jun, 2024 Expired
US8835452 Polymorphic forms α, β and γ of rifaximin 19 Jun, 2024 Expired
US8853231 Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin 19 Jun, 2024 Expired
US10376584 Stable pharmaceutical formulations of methylnaltrexone 08 Apr, 2024 Expired
US8552025 Stable methylnaltrexone preparation 08 Apr, 2024 Expired
US9669096 Stable pharmaceutical formulations of methylnaltrexone 08 Apr, 2024 Expired
US7799897 Guanylate cyclase receptor agonists for the treatment of tissue inflammation and carcinogenesis 09 Jun, 2022 Expired
US8637451 Guanylate cyclase receptor agonists for the treatment of tissue inflammation and carcinogenesis 28 Mar, 2022 Expired
US10064878 Controlled release and taste masking oral pharmaceutical compositions 09 Jun, 2020 Expired
US10105374 Controlled release and taste masking oral pharmaceutical compositions 09 Jun, 2020 Expired
US10143698 Controlled release and taste masking oral pharmaceutical compositions 09 Jun, 2020 Expired
US7410651 Controlled release and taste masking oral pharmaceutical composition 09 Jun, 2020 Expired
US7431943 Controlled release and taste masking oral pharmaceutical compositions 09 Jun, 2020 Expired
US8293273 Controlled release and taste masking oral pharmaceutical composition 09 Jun, 2020 Expired
US8784888 Controlled release and taste masking oral pharmaceutical composition 09 Jun, 2020 Expired
US9320716 Controlled release and taste masking oral pharmaceutical compositions 09 Jun, 2020 Expired
US9532954 Controlled release and taste masking oral pharmaceutical compositions 09 Jun, 2020 Expired
USRE43799 Controlled release and taste masking oral pharmaceutical composition 09 Jun, 2020 Expired
US6861053 Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth 11 Aug, 2019 Expired
US7452857 Methods of treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth 11 Aug, 2019 Expired
US7605240 Methods of treating diarrhea and bloating caused by small intestinal bacterial overgrowth 11 Aug, 2019 Expired
US7718608 Methods of treating a subject suffering from irritable bowel syndrome 11 Aug, 2019 Expired
US7935799 Methods of treating diarrhea caused by small intestinal bacterial overgrowth 11 Aug, 2019 Expired
US6551620 Pellet formulation for the treatment of the intestinal tract 20 Apr, 2018 Expired
US8337886 Pellet formulation for the treatment of the intestinal tract 20 Apr, 2018 Expired
US8496965 Pellet formulation for the treatment of the intenstinal tract 20 Apr, 2018 Expired
US8911778 Pellet formulation for the treatment of the intestinal tract 20 Apr, 2018 Expired
US8940328 Pellet formulation for the treatment of the intestinal tract 20 Apr, 2018 Expired
US8956647 Pellet formulation for the treatment of the intestinal tract 20 Apr, 2018 Expired
US6559158 Use of methylnaltrexone and related compounds to treat chronic opioid use side affects 03 Nov, 2017 Expired
US6413549 Fast-Dispersing solid oral dosage form containing coarse particles 11 Jul, 2017 Expired
US5840737 Omeprazole solution and method for using same 16 Jul, 2016 Expired
US6489346 Substituted benzimidazole dosage forms and method of using same 16 Jul, 2016 Expired
US6645988 Substituted benzimidazole dosage forms and method of using same 16 Jul, 2016 Expired
US6699885 Substituted benzimidazole dosage forms and methods of using same 16 Jul, 2016 Expired
US6780882 Substituted benzimidazole dosage forms and method of using same 16 Jul, 2016 Expired
US7399772 Substituted benzimidazole dosage forms and method of using same 16 Jul, 2016 Expired
USRE45198 Omeprazole solution and method for using same 15 Jul, 2016 Expired
US5914122 Stable budesonide solutions, method of preparing them and use of these solutions as enema preparations and pharmaceutical foams 19 Dec, 2015 Expired
US5616346 Non-aqueous colonic purgative formulations 18 May, 2013 Expired


Given below is the list of recent legal activities going on the following drug patents of Salix.

Activity Date Patent Number
Patent litigations
Maintenance Fee Reminder Mailed 10 Jun, 2024 US8293273 (Litigated)
Expire Patent 03 Jun, 2024 US9320716
Payment of Maintenance Fee, 12th Year, Large Entity 18 Apr, 2024 US8309569 (Litigated)
Payment of Maintenance Fee, 4th Year, Large Entity 21 Mar, 2024 US10792306
Payment of Maintenance Fee, 4th Year, Large Entity 21 Feb, 2024 US10780112
Payment of Maintenance Fee, 4th Year, Large Entity 20 Feb, 2024 US10765667
Payment of Maintenance Fee, 12th Year, Large Entity 23 Jan, 2024 US8247425
Payment of Maintenance Fee, 8th Year, Large Entity 23 Jan, 2024 US9421195
Payment of Maintenance Fee, 4th Year, Large Entity 21 Dec, 2023 US10703763
Payment of Maintenance Fee, 4th Year, Large Entity 19 Dec, 2023 US10709694
Maintenance Fee Reminder Mailed 18 Dec, 2023 US9320716
Sequence Moved to Public Database 08 Dec, 2023 US11834521
Recordation of Patent Grant Mailed 05 Dec, 2023 US11834521
Patent Issue Date Used in PTA Calculation 05 Dec, 2023 US11834521
Email Notification 05 Dec, 2023 US11834521


Salix's Drug Patent Litigations

Salix's drugs have been subject to various legal proceedings, including patent litigations. The earliest legal proceeding was initiated on Jul 11, 2016, against patent number US8865688. The petitioner MycoNovo, Inc. et al., challenged the validity of this patent, with Salix Pharmaceuticals, Ltd. et al. as the respondent. Click below to track the latest information on how companies are challenging Salix's patents.

Patent Proceeding Filing Date Status Respondent Petitioner
Patent litigations
US7041786 March, 2022 Final Written Decision - Appealed
(08 Sep, 2023)
Bausch Health Ireland Limited et al. Mylan Pharmaceuticals Inc. et al.
US7041786 October, 2022 Final Written Decision
(08 Sep, 2023)
Bausch Health Ireland Limited et al. MSN Laboratories Private Ltd. et al.
US7041786 October, 2022 Final Written Decision - Appealed
(08 Sep, 2023)
Bausch Health Ireland Limited et al. MSN Laboratories Private Ltd. et al.
US7041786 March, 2022 Final Written Decision
(08 Sep, 2023)
Bausch Health Ireland Limited et al. Mylan Pharmaceuticals Inc. et al.
US9919024 June, 2022 Institution Denied
(04 Jan, 2023)
Bausch Health Ireland Limited et al. Mylan Pharmaceuticals Inc. et al.
US9925231 June, 2022 Institution Denied
(04 Jan, 2023)
Bausch Health Ireland Limited et al. Mylan Pharmaceuticals Inc. et al.
US9610321 June, 2022 Institution Denied
(04 Jan, 2023)
Bausch Health Ireland Limited et al. Mylan Pharmaceuticals Inc. et al.
US9616097 June, 2022 Institution Denied
(04 Jan, 2023)
Bausch Health Ireland Limited et al. Mylan Pharmaceuticals Inc. et al.
US9320716 October, 2017 Terminated-Settled
(23 Apr, 2018)
Cosmo Technologies Limited Argentum Pharmaceuticals LLC
US9320716 March, 2017 Terminated-Settled
(17 Jan, 2018)
US8784888 March, 2017 Terminated-Settled
(20 Sep, 2017)
US8865688 December, 2015 FWD Entered
(19 May, 2017)
SALIX PHARMACEUTICALS, LTD. GeneriCo, LLC
US8865688 December, 2015 Final Written Decision
(19 May, 2017)
SALIX PHARMACEUTICALS, LTD. et al. GeneriCo, LLC et al.
US8865688 July, 2016 Terminated
(30 Nov, 2016)
Salix Pharmaceuticals, Ltd. et al. Mylan Pharmaceuticals Inc. et al.
US8865688 July, 2016 Terminated
(30 Nov, 2016)
Salix Pharmaceuticals, Ltd. et al. MycoNovo, Inc. et al.


Salix Drug Patents' Oppositions Filed in EPO

Salix drug patents have faced multiple oppositions in the European Patent Office. The earliest opposition was filed on Feb 08, 2008, by Interquim, S.A. De C.V.. This opposition was filed on patent number EP04005541A. Click below to reveal the latest opposition data.


Application Filing Date Opposition Party Legal Status
Patent litigations
EP09818544A Sep, 2020 Hollatz, Christian Granted and Under Opposition
EP09818544A Sep, 2020 Alfred E. Tiefenbacher (GmbH & Co. KG) Granted and Under Opposition
EP09818544A Sep, 2020 STADA Arzneimittel AG Granted and Under Opposition
EP09818544A Sep, 2020 Accord Healthcare Ltd Granted and Under Opposition
EP09818544A Sep, 2020 Teva Pharmaceutical Industries Ltd Granted and Under Opposition
EP09818544A Sep, 2020 Aera A/S Granted and Under Opposition
EP09818544A Aug, 2020 Lederer & Keller Patentanwälte Partnerschaft mbB Granted and Under Opposition
EP09818544A Aug, 2020 CMS Cameron McKenna Nabarro Olswang LLP Granted and Under Opposition
EP09715020A Dec, 2019 Teva Pharmaceutical Industries Ltd Granted and Under Opposition
EP09715020A Dec, 2019 Lederer & Keller Patentanwälte Partnerschaft mbB Granted and Under Opposition
EP09715020A Dec, 2019 Sandoz GmbH Granted and Under Opposition
EP10184575A Sep, 2015 Actavis Group PTC ehf Revoked
EP10184575A Sep, 2015 Fresenius Kabi Deutschland GmbH Revoked
EP10184684A Sep, 2015 Actavis Group PTC ehf Revoked
EP04759349A Sep, 2015 Actavis Group PTC ehf Patent maintained as amended
EP04759349A Sep, 2015 Fresenius Kabi Deutschland GmbH Patent maintained as amended
EP10184684A Sep, 2015 Fresenius Kabi Deutschland GmbH Revoked
EP05004695A Jun, 2015 Sandoz GmbH Revoked
EP02721604A Apr, 2010 Hill, Christopher Michael Patent maintained as amended
EP02721604A Apr, 2010 CombiMab, Inc. Patent maintained as amended
EP03758361A May, 2009 Teva Pharmaceutical Industries LTD. Opposition procedure closed
EP04005541A Feb, 2008 Interquim, S.A. De C.V. Opposition rejected


Salix's Family Patents

Salix drugs have patent protection in a total of 54 countries. It's US patent count contributes only to 28.7% of its total global patent coverage. 7 countries have all of their patents expired or invalidated which has opened up potential generic launch opportunities in these countries. Click below to unlock the full patent family tree.

Family Patents



Salix Drug List

Given below is the complete list of Salix's drugs and the patents protecting them.


1. Apriso

Apriso is protected by 7 patents, out of which 6 have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US8865688 Compositions and methods for treatment of bowel diseases with granulated mesalamine 01 May, 2030
(4 years from now)
Active
US6551620 Pellet formulation for the treatment of the intestinal tract 20 Apr, 2018
(7 years ago)
Expired
US8337886 Pellet formulation for the treatment of the intestinal tract 20 Apr, 2018
(7 years ago)
Expired
US8496965 Pellet formulation for the treatment of the intenstinal tract 20 Apr, 2018
(7 years ago)
Expired
US8911778 Pellet formulation for the treatment of the intestinal tract 20 Apr, 2018
(7 years ago)
Expired
US8940328 Pellet formulation for the treatment of the intestinal tract 20 Apr, 2018
(7 years ago)
Expired
US8956647 Pellet formulation for the treatment of the intestinal tract 20 Apr, 2018
(7 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Apriso's drug page


2. Fenoglide

Fenoglide is protected by 4 patents, out of which all have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US7658944 Solid dosage form comprising a fibrate 09 Dec, 2024
(1 year, 30 days ago)
Expired
US8124125 Solid dosage form comprising a fibrate 01 Oct, 2024
(1 year, 3 months ago)
Expired
US8481078 Solid dosage form comprising a fibrate 01 Oct, 2024
(1 year, 3 months ago)
Expired
US9173847 Tablet comprising a fibrate 01 Oct, 2024
(1 year, 3 months ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Fenoglide's drug page


3. Metozolv Odt

Metozolv Odt is protected by 1 patent, which has expired already. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US6413549 Fast-Dispersing solid oral dosage form containing coarse particles 11 Jul, 2017
(8 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Metozolv Odt's drug page


4. Moviprep

Moviprep is protected by 2 patents, out of which all have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US7169381 Colon cleansing compositions and methods 01 Sep, 2024
(1 year, 4 months ago)
Expired
US7658914 Colon cleansing compositions 01 Sep, 2024
(1 year, 4 months ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Moviprep's drug page


5. Osmoprep

Osmoprep is protected by 2 patents, out of which 1 has expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US7687075 Colonic purgative composition with soluble binding agent 22 Jun, 2028
(2 years from now)
Active
US5616346 Non-aqueous colonic purgative formulations 18 May, 2013
(12 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Osmoprep's drug page


Explore Our Curated Drug Screens

Drugs Generating Over $1 Billion in Annual Revenue
Explore the top-performing drugs that dominate the pharmaceutical industry
View List
NCE-1 Patent Expiry in the Next 1 Year
Identify opportunities as new chemical entity (NCE-1) patents approach expiry
View List
Recently Granted Patents in EP
Find the opportunity to file Oppositions
View List

6. Plenvu

Plenvu is protected by 11 patents, out of which none have expired yet. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US10016504 Compositions 10 Sep, 2033
(7 years from now)
Active
US10918723 Colon cleansing compositions and methods of use 10 Sep, 2033
(7 years from now)
Active
US12083179 Colon cleansing compositions and method of use 10 Sep, 2033
(7 years from now)
Active
US8999313 Compositions 10 Sep, 2033
(7 years from now)
Active
US9326969 Compositions 10 Sep, 2033
(7 years from now)
Active
US9707297 Compositions 10 Sep, 2033
(7 years from now)
Active
US9592252 Colonoscopy—preparation 11 Aug, 2032
(6 years from now)
Active
US10646512 Colonoscopy - preparation 25 Mar, 2032
(6 years from now)
Active
US10780112 Colonoscopy-preparation 09 Mar, 2032
(6 years from now)
Active
US10792306 Colonoscopy—preparation 09 Mar, 2032
(6 years from now)
Active
US11529368 Colonoscopy—preparation 09 Mar, 2032
(6 years from now)
Active

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Plenvu's drug page


7. Relistor

Relistor is protected by 16 patents, out of which 4 have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US10307417 Oral formulations and lipophilic salts of methylnaltrexone 10 Mar, 2031
(5 years from now)
Active
US10376505 Oral formulations and lipophilic salts of methylnaltrexone 10 Mar, 2031
(5 years from now)
Active
US8524276 Oral formulations and lipophilic salts of methylnaltrexone 10 Mar, 2031
(5 years from now)
Active
US8956651 Oral formulations and lipophilic salts of methylnal trexone 10 Mar, 2031
(5 years from now)
Active
US9314461 Oral formulations and lipophilic salts of methylnaltrexone 10 Mar, 2031
(5 years from now)
Active
US8247425 Peripheral opioid receptor antagonists and uses thereof 31 Dec, 2030
(4 years from now)
Active
US8420663 Peripheral opioid receptor antagonists and uses thereof 30 Sep, 2029
(3 years from now)
Active
US8822490 Peripheral opioid receptor antagonists and uses thereof 30 Sep, 2029
(3 years from now)
Active
US9180125 Peripheral opioid receptor antagonists and uses thereof 30 Sep, 2029
(3 years from now)
Active
US9492445 Peripheral opioid receptor antagonists and uses thereof 30 Sep, 2029
(3 years from now)
Active
US9724343 Peripheral opioid receptor antagonists and uses thereof 30 Sep, 2029
(3 years from now)
Active
US12303592 Formulations for parenteral delivery of compounds and uses thereof 03 Aug, 2027
(1 year, 6 months from now)
Active
US10376584 Stable pharmaceutical formulations of methylnaltrexone 08 Apr, 2024
(1 year, 9 months ago)
Expired
US8552025 Stable methylnaltrexone preparation 08 Apr, 2024
(1 year, 9 months ago)
Expired
US9669096 Stable pharmaceutical formulations of methylnaltrexone 08 Apr, 2024
(1 year, 9 months ago)
Expired
US6559158 Use of methylnaltrexone and related compounds to treat chronic opioid use side affects 03 Nov, 2017
(8 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Relistor's drug page


8. Trulance

Trulance is protected by 12 patents, out of which 2 have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US10011637 Ultra-pure agonists of guanylate cyclase C, method of making and using same 05 Jun, 2034
(8 years from now)
Active
US11142549 Ultra-pure agonists of guanylate cyclase C, method of making and using same 05 Jun, 2034
(8 years from now)
Active
US11834521 Ultra-pure agonists of guanylate cyclase C, method of making and using same 05 Jun, 2034
(8 years from now)
Active
US12146003 Ultra-pure agonists of guanylate cyclase C, method of making and using same 05 Jun, 2034
(8 years from now)
Active
US9616097 Formulations of guanylate cyclase C agonists and methods of use 20 Aug, 2032
(6 years from now)
Active
US11319346 Ultra-pure agonists of guanylate cyclase C, method of making and using same 01 Mar, 2032
(6 years from now)
Active
US9610321 Formulations of guanylate cyclase C agonists and methods of use 15 Sep, 2031
(5 years from now)
Active
US9919024 Formulations of guanylate cyclase C agonists and methods of use 15 Sep, 2031
(5 years from now)
Active
US9925231 Formulations of guanylate cyclase C agonists and methods of use 15 Sep, 2031
(5 years from now)
Active
US7041786 Guanylate cyclase receptor agonists for the treatment of tissue inflammation and carcinogenesis 30 Jan, 2028
(2 years from now)
Active
US7799897 Guanylate cyclase receptor agonists for the treatment of tissue inflammation and carcinogenesis 09 Jun, 2022
(3 years ago)
Expired
US8637451 Guanylate cyclase receptor agonists for the treatment of tissue inflammation and carcinogenesis 28 Mar, 2022
(3 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Trulance's drug page


9. Uceris

Uceris is protected by 16 patents, out of which 11 have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US10307375 Controlled release and taste masking oral pharmaceutical composition 07 Sep, 2031
(5 years from now)
Active
US10660858 Controlled release and taste masking oral pharmaceutical composition 07 Sep, 2031
(5 years from now)
Active
US8895064 Controlled release and taste masking oral pharmaceutical composition 07 Sep, 2031
(5 years from now)
Active
US9132093 Controlled release and taste making oral pharmaceutical composition 07 Sep, 2031
(5 years from now)
Active
US9192581 Controlled release and taste masking oral pharmaceutical composition 07 Sep, 2031
(5 years from now)
Active
US10064878 Controlled release and taste masking oral pharmaceutical compositions 09 Jun, 2020
(5 years ago)
Expired
US10105374 Controlled release and taste masking oral pharmaceutical compositions 09 Jun, 2020
(5 years ago)
Expired
US10143698 Controlled release and taste masking oral pharmaceutical compositions 09 Jun, 2020
(5 years ago)
Expired
US7410651 Controlled release and taste masking oral pharmaceutical composition 09 Jun, 2020
(5 years ago)
Expired
US7431943 Controlled release and taste masking oral pharmaceutical compositions 09 Jun, 2020
(5 years ago)
Expired
US8293273 Controlled release and taste masking oral pharmaceutical composition 09 Jun, 2020
(5 years ago)
Expired
US8784888 Controlled release and taste masking oral pharmaceutical composition 09 Jun, 2020
(5 years ago)
Expired
US9320716 Controlled release and taste masking oral pharmaceutical compositions 09 Jun, 2020
(5 years ago)
Expired
US9532954 Controlled release and taste masking oral pharmaceutical compositions 09 Jun, 2020
(5 years ago)
Expired
USRE43799 Controlled release and taste masking oral pharmaceutical composition 09 Jun, 2020
(5 years ago)
Expired
US5914122 Stable budesonide solutions, method of preparing them and use of these solutions as enema preparations and pharmaceutical foams 19 Dec, 2015
(10 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Uceris's drug page


10. Visicol

Visicol is protected by 1 patent, which has expired already. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US5616346 Non-aqueous colonic purgative formulations 18 May, 2013
(12 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Visicol's drug page


11. Xifaxan

Xifaxan is protected by 35 patents, out of which 14 have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US10314828 Methods of treating hepatic encephalopathy 02 Oct, 2029
(3 years from now)
Active
US8642573 Methods of treating hepatic encephalopathy 02 Oct, 2029
(3 years from now)
Active
US8969398 Methods of treating hepatic encephalopathy 02 Oct, 2029
(3 years from now)
Active
US10314828 Methods of treating hepatic encephalopathy 24 Jul, 2029
(3 years from now)
Active
US10335397 Methods of treating hepatic encephalopathy 24 Jul, 2029
(3 years from now)
Active
US10709694 Methods of treating hepatic encephalopathy 24 Jul, 2029
(3 years from now)
Active
US7928115 Methods of treating travelers diarrhea and hepatic encephalopathy 24 Jul, 2029
(3 years from now)
Active
US8829017 Methods of treating traveler's diarrhea and hepatic encephalopathy 24 Jul, 2029
(3 years from now)
Active
US8946252 Methods of treating traveler's diarrhea and hepatic encephalopathy 24 Jul, 2029
(3 years from now)
Active
US9421195 Methods of treating hepatic encephalopathy 24 Jul, 2029
(3 years from now)
Active
US9629828 Methods of treating traveler's diarrhea and hepatic encephalopathy 24 Jul, 2029
(3 years from now)
Active
US8309569 Methods for treating diarrhea-associated irritable bowel syndrome 18 Jul, 2029
(3 years from now)
Active
US10456384 Methods for treating irritable bowel syndrome (IBS) 26 Feb, 2029
(3 years from now)
Active
US10765667 Methods for treating irritable bowel syndrome (IBS) 26 Feb, 2029
(3 years from now)
Active
US11564912 Methods for treating irritable bowel syndrome (IBS) 26 Feb, 2029
(3 years from now)
Active
US11779571 Methods for treating irritable bowel syndrome (IBS) 26 Feb, 2029
(3 years from now)
Active
US8193196 Polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations 02 Sep, 2027
(1 year, 7 months from now)
Active
US10703763 Polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations 27 Feb, 2026
(a month from now)
Active
US8518949 Polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations 27 Feb, 2026
(a month from now)
Active
US8741904 Polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations 27 Feb, 2026
(a month from now)
Active
US9271968 Polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations 27 Feb, 2026
(a month from now)
Active
US7906542 Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin 01 Jun, 2025
(7 months ago)
Expired
US7915275 Use of polymorphic forms of rifaximin for medical preparations 23 Feb, 2025
(10 months ago)
Expired
US7045620 Polymorphous forms of rifaximin, processes for their production and use thereof in medicinal preparations 19 Jun, 2024
(1 year, 6 months ago)
Expired
US7612199 Polymorphic forms α, β, and γ of rifaximin 19 Jun, 2024
(1 year, 6 months ago)
Expired
US7902206 Polymorphic forms α, β and γ of rifaximin 19 Jun, 2024
(1 year, 6 months ago)
Expired
US8158644 Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin 19 Jun, 2024
(1 year, 6 months ago)
Expired
US8158781 Polymorphic forms α, β and γ of rifaximin 19 Jun, 2024
(1 year, 6 months ago)
Expired
US8835452 Polymorphic forms α, β and γ of rifaximin 19 Jun, 2024
(1 year, 6 months ago)
Expired
US8853231 Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin 19 Jun, 2024
(1 year, 6 months ago)
Expired
US6861053 Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth 11 Aug, 2019
(6 years ago)
Expired
US7452857 Methods of treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth 11 Aug, 2019
(6 years ago)
Expired
US7605240 Methods of treating diarrhea and bloating caused by small intestinal bacterial overgrowth 11 Aug, 2019
(6 years ago)
Expired
US7718608 Methods of treating a subject suffering from irritable bowel syndrome 11 Aug, 2019
(6 years ago)
Expired
US7935799 Methods of treating diarrhea caused by small intestinal bacterial overgrowth 11 Aug, 2019
(6 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Xifaxan's drug page


12. Zegerid

Zegerid is protected by 7 patents, out of which all have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US5840737 Omeprazole solution and method for using same 16 Jul, 2016
(9 years ago)
Expired
US6489346 Substituted benzimidazole dosage forms and method of using same 16 Jul, 2016
(9 years ago)
Expired
US6645988 Substituted benzimidazole dosage forms and method of using same 16 Jul, 2016
(9 years ago)
Expired
US6699885 Substituted benzimidazole dosage forms and methods of using same 16 Jul, 2016
(9 years ago)
Expired
US6780882 Substituted benzimidazole dosage forms and method of using same 16 Jul, 2016
(9 years ago)
Expired
US7399772 Substituted benzimidazole dosage forms and method of using same 16 Jul, 2016
(9 years ago)
Expired
USRE45198 Omeprazole solution and method for using same 15 Jul, 2016
(9 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Zegerid's drug page