Ophthalmology Therapeutics

1. Durezol patent expiration

Treatment: NA

DUREZOL IPR and PTAB Proceedings
Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US6114319

(Pediatric)

SANDOZ Compositions containing difluprednate
Nov, 2019

(6 years ago)

US6114319 SANDOZ Compositions containing difluprednate
May, 2019

(6 years ago)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Jun 23, 2013
New Indication(I-653) Jun 13, 2015
M(M-127) Mar 22, 2016
Pediatric Exclusivity(PED) Sep 22, 2016
Orphan Drug Exclusivity(ODE) Jun 13, 2019
Orphan Drug Exclusivity(ODE-26) Jun 13, 2019

Drugs and Companies using DIFLUPREDNATE ingredient

NCE-1 date: 23 September, 2015

Market Authorisation Date: 23 June, 2008

Dosage: EMULSION

How can I launch a generic of DUREZOL before it's drug patent expiration?
More Information on Dosage

DUREZOL family patents

Family Patents

2. Izervay patent expiration

Treatment: Treatment of geographic atrophy secondary to age-related macular degeneration by administerting avacincaptad pegol to the eye

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents protects the active chemical substance. Only drug patent owner can launch products that use this active substance.
US10947544 ASTELLAS Aptamer therapeutics useful in the treatment of complement-related disorders
Feb, 2025

(1 year, 7 days ago)

US7803931 ASTELLAS Aptamer therapeutics useful in the treatment of complement-related disorders
Feb, 2025

(1 year, 7 days ago)

US7538211 ASTELLAS Aptamer therapeutics useful in the treatment of complement-related disorders
Feb, 2025

(1 year, 7 days ago)

US9617546 ASTELLAS Aptamer therapeutics useful in the treatment of complement-related disorders
Feb, 2027

(11 months from now)

US7579456 ASTELLAS Aptamer therapeutics useful in the treatment of complement-related disorders
Feb, 2027

(11 months from now)

These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US11491176 ASTELLAS Methods for treating or preventing ophthalmological conditions
Jul, 2034

(8 years from now)

US11273171 ASTELLAS Methods for treating or preventing ophthalmological conditions
Jul, 2034

(8 years from now)

US8236773 ASTELLAS Aptamer therapeutics useful in the treatment of complement-related disorders
Nov, 2026

(8 months from now)

US12016875 ASTELLAS Methods for treating or preventing ophthalmological conditions
Jul, 2034

(8 years from now)




Drugs and Companies using AVACINCAPTAD PEGOL SODIUM ingredient

Market Authorisation Date: 04 August, 2023

Dosage: SOLUTION

More Information on Dosage

IZERVAY family patents

Family Patents

Stay ahead of others in designing the generic launch strategy of these 5 blockbuster drugs expiring in next 5 years.

Get the exclusive patent insights now. Don't be the last to know.

3. Lastacaft patent expiration

Treatment: Use of lastacaft to temporary relieve itchy eyes due to pollen, ragweed, grass, animal hair and dander

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US5468743 ABBVIE Imidazo[2,1-b]benzazepine derivatives, compositions and method of use
Nov, 2013

(12 years ago)

US8664215 ABBVIE Ocular allergy treatments with alcaftadine
Dec, 2027

(1 year, 9 months from now)

US10617695 ABBVIE Ophthalmic compositions containing alcaftadine
Mar, 2027

(1 year, 25 days from now)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Jul 28, 2015

Drugs and Companies using ALCAFTADINE ingredient

NCE-1 date: 28 July, 2014

Market Authorisation Date: 28 July, 2010

Dosage: SOLUTION/DROPS

How can I launch a generic of LASTACAFT before it's drug patent expiration?
More Information on Dosage

LASTACAFT family patents

Family Patents

4. Lumigan patent expiration

Treatment: Lumigan is a prostaglandin analog indicated for the reduction of elevated intraocular pressure in patients with open angle glaucoma or ocular hypertension; A method of lowering intraocular pressure; M...

LUMIGAN's oppositions filed in EPO
LUMIGAN IPR and PTAB Proceedings
Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents protects the active chemical substance. Only drug patent owner can launch products that use this active substance.
US7851504 ABBVIE Enhanced bimatoprost ophthalmic solution
Jun, 2027

(1 year, 3 months from now)

These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US5688819 ABBVIE Cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
Aug, 2014

(11 years ago)

US6403649 ABBVIE Non-acidic cyclopentane heptanoic acid,2-cycloalkyl or arylalkyl derivatives as therapeutic agents
Sep, 2012

(13 years ago)

US8017655 ABBVIE Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
Nov, 2012

(13 years ago)

US9155716 ABBVIE Enhanced bimatoprost ophthalmic solution
Mar, 2025

(11 months ago)

US9241918 ABBVIE Enhanced bimatoprost ophthalmic solution
Mar, 2025

(11 months ago)

US8299118 ABBVIE Enhanced bimatoprost ophthalmic solution
Mar, 2025

(11 months ago)

US8309605 ABBVIE Enhanced bimatoprost ophthalmic solution
Mar, 2025

(11 months ago)

US8338479 ABBVIE Enhanced bimatoprost ophthalmic solution
Mar, 2025

(11 months ago)

US8524777 ABBVIE Enhanced bimatoprost ophthalmic solution
Mar, 2025

(11 months ago)

US8586630 ABBVIE Enhanced bimatoprost ophthalmic solution
Mar, 2025

(11 months ago)

US8278353 ABBVIE Enhanced bimatoprost ophthalmic solution
Mar, 2025

(11 months ago)

US8933127 ABBVIE Enhanced bimatoprost ophthalmic solution
Mar, 2025

(11 months ago)

US8933120 ABBVIE Enhanced bimatoprost ophthalmic solution
Mar, 2025

(11 months ago)

US8772338 ABBVIE Enhanced bimatoprost ophthalmic solution
Mar, 2025

(11 months ago)




Drug Exclusivity Drug Exclusivity Expiration
New Product(NP) Aug 31, 2013

Drugs and Companies using BIMATOPROST ingredient

Market Authorisation Date: 16 March, 2001

Dosage: SOLUTION/DROPS

How can I launch a generic of LUMIGAN before it's drug patent expiration?
More Information on Dosage

LUMIGAN family patents

Family Patents

5. Macugen patent expiration

Treatment: Treatment of vegf mediated ocular disease.

MACUGEN IPR and PTAB Proceedings
Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US6051698 BAUSCH Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes
May, 2015

(10 years ago)

US6113906 BAUSCH Water-soluble non-antigenic polymer linkable to biologically active material
Oct, 2013

(12 years ago)

US5919455 BAUSCH Non-antigenic branched polymer conjugates
Oct, 2013

(12 years ago)

US6011020 BAUSCH Nucleic acid ligand complexes
Jan, 2017

(9 years ago)

US5932462 BAUSCH Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
Aug, 2016

(9 years ago)




Drugs and Companies using PEGAPTANIB SODIUM ingredient

Market Authorisation Date: 17 December, 2004

Dosage: INJECTABLE

More Information on Dosage

MACUGEN family patents

Family Patents

6. Miebo patent expiration

Treatment: Treatment of the signs and symptoms of dry eye disease (ded)

MIEBO IPR and PTAB Proceedings
Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US10576154 BAUSCH Semifluorinated alkane compositions
Oct, 2035

(9 years from now)

US10507132 BAUSCH Topical administration method
Jun, 2037

(11 years from now)

US10449164 BAUSCH Methods of treating ocular disorders using semifluorinated alkanes
Sep, 2033

(7 years from now)

US10369117 BAUSCH Compositions comprising mixtures of semifluorinated alkanes
Sep, 2033

(7 years from now)

US10058615 BAUSCH Semifluorinated alkane compositions
Sep, 2033

(7 years from now)

US11357738 BAUSCH Semifluorinated compounds and their compositions
Sep, 2036

(10 years from now)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) May 18, 2028

Drugs and Companies using PERFLUOROHEXYLOCTANE ingredient

NCE-1 date: 19 May, 2027

Market Authorisation Date: 18 May, 2023

Dosage: SOLUTION/DROPS

More Information on Dosage

MIEBO family patents

Family Patents

7. Nevanac patent expiration

Treatment: Method of treating ocular inflammation

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US5475034 HARROW EYE Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders
Jun, 2014

(11 years ago)

US7834059 HARROW EYE Topical nepafenac formulations
Jan, 2027

(11 months from now)

US8071648 HARROW EYE Topical nepafenac formulations
Dec, 2025

(2 months ago)

US8324281 HARROW EYE Topical nepafenac formulations
Dec, 2025

(2 months ago)




Drugs and Companies using NEPAFENAC ingredient

Market Authorisation Date: 19 August, 2005

Dosage: SUSPENSION/DROPS

More Information on Dosage

NEVANAC family patents

Family Patents

8. Omlonti patent expiration

Treatment: Method of treating open-angle glaucoma or ocular hypertension in patients

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents protects the active chemical substance. Only drug patent owner can launch products that use this active substance.
US10774072 OCUVEX Crystal of N-substituted sulfonamide compound
Jun, 2035

(9 years from now)

US8648097 OCUVEX Pyridylaminoacetic acid compound
Oct, 2029

(3 years from now)

These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US11666563 OCUVEX Pharmaceutical preparation containing pyridyl aminoacetic acid compound
Jul, 2039

(13 years from now)

US11197849 OCUVEX Pharmaceutical formulations comprising a pyridylaminoacetic acid compound
Jan, 2035

(8 years from now)

US10702511 OCUVEX Pharmaceutical formulations comprising a pyridylaminoacetic acid compound
Jan, 2035

(8 years from now)

US10179127 OCUVEX Pharmaceutical formulations comprising a pyridylaminoacetic acid compound
Jan, 2035

(8 years from now)

US9415038 OCUVEX Pharmaceutical formulations comprising a pyridylaminoacetic acid compound
Jan, 2035

(8 years from now)

USRE48183 OCUVEX Pharmaceutical formulations comprising a pyridylaminoacetic acid compound
Jan, 2035

(8 years from now)

US11793798 OCUVEX Pharmaceutical formulations comprising a pyridylaminoacetic acid compound
Jan, 2035

(8 years from now)

US8685986 OCUVEX Medical composition for treatment or prophylaxis of glaucoma
Oct, 2029

(3 years from now)

US10765750 OCUVEX Pharmaceutical composition containing pyridylaminoacetic acid compound
Jan, 2035

(8 years from now)

US12295946 OCUVEX Pharmaceutical Formulations Comprising A Pyridylaminoacetic Acid Compound
Jan, 2035

(8 years from now)

US12290511 OCUVEX Pharmaceutical Preparation Containing Pyridyl Aminoacetic Acid Compound
Dec, 2038

(12 years from now)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Sep 22, 2027

Drugs and Companies using OMIDENEPAG ISOPROPYL ingredient

NCE-1 date: 22 September, 2026

Market Authorisation Date: 22 September, 2022

Dosage: SOLUTION

More Information on Dosage

OMLONTI family patents

Family Patents

9. Rhopressa patent expiration

Treatment: Reduction of elevated intraocular pressure

RHOPRESSA's oppositions filed in EPO
Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents protects the active chemical substance. Only drug patent owner can launch products that use this active substance.
US8450344 ALCON Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds
Jul, 2026

(4 months from now)

US9096569 ALCON Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds
Jul, 2026

(4 months from now)

US10174017 ALCON Dual mechanism inhibitors for the treatment of disease
Jan, 2030

(3 years from now)

US8394826 ALCON Dual mechanism inhibitors for the treatment of disease
Nov, 2030

(4 years from now)

US9931336 ALCON Combination therapy
Mar, 2034

(8 years from now)

US10654844 ALCON Dual mechanism inhibitors for the treatment of disease
Jan, 2030

(3 years from now)

US10588901 ALCON Combination therapy
Mar, 2034

(8 years from now)

US9415043 ALCON Combination therapy
Mar, 2034

(8 years from now)

These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US10532993 ALCON Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds
Jul, 2026

(4 months from now)

US11021456 ALCON Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds
Jul, 2026

(4 months from now)

US11028081 ALCON Dual mechanism inhibitors for the treatment of disease
Jan, 2030

(3 years from now)

US10882840 ALCON Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds
Jul, 2026

(4 months from now)

US11618748 ALCON Dual mechanism inhibitors for the treatment of disease
Jan, 2030

(3 years from now)

US11020385 ALCON Combination therapy
Mar, 2034

(8 years from now)

US11185538 ALCON Compositions for treating glaucoma or reducing intraocular pressure
Mar, 2034

(8 years from now)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Dec 18, 2022

Drugs and Companies using NETARSUDIL MESYLATE ingredient

NCE-1 date: 18 December, 2021

Market Authorisation Date: 18 December, 2017

Dosage: SOLUTION/DROPS

How can I launch a generic of RHOPRESSA before it's drug patent expiration?
More Information on Dosage

RHOPRESSA family patents

Family Patents

10. Travatan patent expiration

Treatment: Method of stabilizing prostaglandin; Method for treating glaucoma and ocular hypertension

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US5631287 ALCON Storage-stable prostaglandin compositions
Dec, 2014

(11 years ago)

US6011062 ALCON Storage-stable prostaglandin compositions
Dec, 2014

(11 years ago)

US5510383 ALCON Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension
Aug, 2013

(12 years ago)

US5889052 ALCON Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension
Dec, 2014

(11 years ago)

US5849792 ALCON Storage-stable prostaglandin compositions
Dec, 2014

(11 years ago)




Drugs and Companies using TRAVOPROST ingredient

Market Authorisation Date: 16 March, 2001

Dosage: SOLUTION/DROPS

How can I launch a generic of TRAVATAN before it's drug patent expiration?
More Information on Dosage

TRAVATAN family patents

Family Patents

11. Visudyne patent expiration

Treatment: Use of the drug product in photodynamic therapeutic protocols for the treatment of age-related macular degeneration and related conditions involving unwanted neovasculature in the eye

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US5756541 BAUSCH Vision through photodynamic therapy of the eye
Mar, 2016

(9 years ago)

US5770619 BAUSCH Method of activating photosensitive agents
Jan, 2015

(11 years ago)

US5798349 BAUSCH Use of green porphyrins to treat neovasculature in the eye
Aug, 2015

(10 years ago)

US5707608 BAUSCH Methods of making liposomes containing hydro-monobenzoporphyrin photosensitizer
Aug, 2015

(10 years ago)




Drugs and Companies using VERTEPORFIN ingredient

Market Authorisation Date: 12 April, 2000

Dosage: INJECTABLE

More Information on Dosage

VISUDYNE family patents

Family Patents

12. Vizz patent expiration

Treatment: Treatment of presbyopia

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US12414942 LENZ NA
Mar, 2044

(18 years from now)

US10052313 LENZ Compositions And Methods For The Treatment Of Presbyopia
Mar, 2034

(8 years from now)

US11179328 LENZ Compositions And Methods For The Treatment Of Presbyopia
Mar, 2034

(8 years from now)

US12128036 LENZ Compositions And Methods For Storage Stable Ophthalmic Drugs
Oct, 2039

(13 years from now)

US9844537 LENZ Compositions And Methods For The Treatment Of Presbyopia
Mar, 2034

(8 years from now)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Jul 31, 2030

Drugs and Companies using ACECLIDINE HYDROCHLORIDE ingredient

NCE-1 date: 31 July, 2029

Market Authorisation Date: 31 July, 2025

Dosage: SOLUTION/DROPS

More Information on Dosage

VIZZ family patents

Family Patents

13. Vyzulta patent expiration

Treatment: Reduction of intraocular pressure (iop) in patients with open-angle glaucoma or ocular hypertension

VYZULTA's oppositions filed in EPO
Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents protects the active chemical substance. Only drug patent owner can launch products that use this active substance.
US6211233 BAUSCH Prostaglandin pharmaceutical compositions
Jun, 2018

(7 years ago)

US7910767 BAUSCH Prostaglandin derivatives
Jan, 2025

(1 year, 1 month ago)

US8058467 BAUSCH Prostaglandin derivatives
Feb, 2029

(3 years from now)

US7273946 BAUSCH Prostaglandin derivatives
Oct, 2025

(4 months ago)

These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US7629345 BAUSCH Prostaglandin derivatives
Jan, 2025

(1 year, 1 month ago)




Drugs and Companies using LATANOPROSTENE BUNOD ingredient

Market Authorisation Date: 02 November, 2017

Dosage: SOLUTION/DROPS

How can I launch a generic of VYZULTA before it's drug patent expiration?
More Information on Dosage

VYZULTA family patents

Family Patents

14. Xiidra patent expiration

Treatment: Treatment of signs and symptoms of dry eye disease (ded); Treatment of the signs and symptoms of dry eye disease (ded)

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents protects the active chemical substance. Only drug patent owner can launch products that use this active substance.
US7928122 BAUSCH Modulators of cellular adhesion
Nov, 2024

(1 year, 3 months ago)

US7745460 BAUSCH Modulators of cellular adhesion
Nov, 2024

(1 year, 3 months ago)

US9890141 BAUSCH Crystalline pharmaceutical and methods of preparation and use thereof
Oct, 2030

(4 years from now)

US7314938 BAUSCH Modulators of cellular adhesion
Mar, 2025

(11 months ago)

US8084047 BAUSCH Compositions and methods for treatment of eye disorders
May, 2026

(2 months from now)

These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US8592450 BAUSCH Compositions and methods for treatment of eye disorders
May, 2026

(2 months from now)

US8367701 BAUSCH Crystalline pharmaceutical and methods of preparation and use thereof
Apr, 2029

(3 years from now)

US9216174 BAUSCH Modulators of cellular adhesion
Nov, 2024

(1 year, 3 months ago)

US7790743 BAUSCH Modulators of cellular adhesion
Nov, 2024

(1 year, 3 months ago)

US8168655 BAUSCH Compositions and methods for treatment of eye disorders
May, 2029

(3 years from now)

US10124000 BAUSCH Modulators of cellular adhesion
Nov, 2024

(1 year, 3 months ago)

US9447077 BAUSCH Crystalline pharmaceutical and methods of preparation and use thereof
Apr, 2029

(3 years from now)

US8927574 BAUSCH Crystalline pharmaceutical and methods of preparation and use thereof
Nov, 2030

(4 years from now)

US9085553 BAUSCH LFA-1 inhibitor and methods of preparation and polymorph thereof
Jul, 2033

(7 years from now)

US11058677 BAUSCH LFA-1 inhibitor formulations
Dec, 2033

(7 years from now)

US9353088 BAUSCH Crystalline pharmaceutical and methods of preparation and use thereof
Oct, 2030

(4 years from now)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Jul 11, 2021

Drugs and Companies using LIFITEGRAST ingredient

NCE-1 date: 11 July, 2020

Market Authorisation Date: 11 July, 2016

Dosage: SOLUTION/DROPS

How can I launch a generic of XIIDRA before it's drug patent expiration?
More Information on Dosage

XIIDRA family patents

Family Patents

15. Zioptan patent expiration

Treatment: Reduction of elevated intraocular pressure in patients with open angle glaucoma or ocular hypertension

ZIOPTAN's oppositions filed in EPO
ZIOPTAN IPR and PTAB Proceedings
Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US5886035 THEA Difluoroprostaglandin derivatives and their use
Dec, 2017

(8 years ago)

US10864159 THEA Method and composition for treating ocular hypertension and glaucoma
May, 2029

(3 years from now)

US9999593 THEA Method and composition for treating ocular hypertension and glaucoma
May, 2029

(3 years from now)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Feb 10, 2017

Drugs and Companies using TAFLUPROST ingredient

NCE-1 date: 11 February, 2016

Market Authorisation Date: 10 February, 2012

Dosage: SOLUTION/DROPS

How can I launch a generic of ZIOPTAN before it's drug patent expiration?
More Information on Dosage

ZIOPTAN family patents

Family Patents