Harrow Eye Drug Patent Portfolio

Harrow Eye owns 10 orange book drugs protected by 41 US patents with Iheezo having the least patent protection, holding only 1 patent. And Moxeza with maximum patent protection, holding 8 patents. Given below is the list of Harrow Eye's drug patents along with their expiration dates.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US12059449 Ophthalmic composition for treatment of dry eye disease 01 Apr, 2042
Active
US11413323 Ophthalmic composition for treatment of dry eye disease 11 Oct, 2039
Active
US11154513 Semifluorinated compounds 20 Nov, 2038
Active
US10792271 Topical formulations of chloroprocaine and methods of using same 15 Sep, 2038
Active
US10813976 Ophthalmic compositions comprising ciclosporin 22 Sep, 2037
Active
US9254286 Ophthalmic formulations of cetirizine and methods of use 09 Jan, 2033
Active
US9254286 Ophthalmic formulations of cetirizine and methods of use 09 Jul, 2032
Active
US8921337 Carboxyvinyl polymer-containing nanoparticle suspensions 31 Mar, 2032
Active
US8614178 Pharmaceutical composition for treatment of dry eye syndrome 13 Dec, 2030
Active
US9662398 Carboxylvinyl polymer-containing nanoparticle suspensions 01 Dec, 2030
Active
US8829005 Ophthalmic formulations of cetirizine and methods of use 15 Sep, 2030
Active
US8829005 Ophthalmic formulations of cetirizine and methods of use 15 Mar, 2030
Active
US9750684 Ophthalmic formulations of cetirizine and methods of use 15 Mar, 2030
Active
US9993471 Ophthalmic formulations of cetirizine and methods of use 15 Mar, 2030
Active
US8128960 Low viscosity, highly flocculated triamcinolone acetonide suspensions for intravitreal injection 17 Dec, 2029
Active
US9132071 Compositions containing quaternary ammonium compounds 02 Jun, 2029
Active
US8450311 Pharmaceutical compositions containing a fluoroquinolone antibiotic drug 29 May, 2029
Active
US9114168 Pharmaceutical compositions containing a fluoroquinolone antibiotic drug 29 May, 2029
Active
US8211880 Low viscosity, highly flocculated triamcinolone acetonide suspensions for intravitreal injection 10 Mar, 2029
Active
US7795316 Topical ophthalmic compositions containing tobramycin and dexamethasone 03 Aug, 2028
Active
US8101582 Topical ophthalmic compositions containing tobramycin and dexamethasone 19 Dec, 2027
Active
US8450287 Topical ophthalmic compositions containing tobramycin and dexamethasone 19 Dec, 2027
Active
US8298568 Oil-in-water type emulsion with low concentration of cationic agent and positive zeta potential 03 Nov, 2027
Active
US7834059 Topical nepafenac formulations 31 Jan, 2027
Active
US11612658 Oil-in-water emulsions comprising cetalkonium chloride and methods of making and using the same 27 Jan, 2026
Active
US7973081 Emulsion compositions containing quaternary ammonium compounds 27 Jan, 2026
Active
US8524779 Emulsion compositions containing quaternary ammonium compounds 27 Jan, 2026
Active
US9220694 Emulsion compositions containing cetalkonium chloride 27 Jan, 2026
Active
US9956289 Emulsion compositions containing quaternary ammonium compounds 27 Jan, 2026
Active
US8071648 Topical nepafenac formulations 02 Dec, 2025
Active
US8324281 Topical nepafenac formulations 02 Dec, 2025
Active
US7947295 Ophthalmic compositions containing a synergistic combination of two polymers 08 Jun, 2024 Expired
US6716830 Ophthalmic antibiotic compositions containing moxifloxacin 29 Mar, 2020 Expired
US7671070 Method of treating ophthalmic infections with moxifloxacin compositions 29 Mar, 2020 Expired
US6395294 Method of visualization of the vitreous during vitrectomy 13 Jan, 2020 Expired
US6716830 Ophthalmic antibiotic compositions containing moxifloxacin 29 Sep, 2019 Expired
US7671070 Method of treating ophthalmic infections with moxifloxacin compositions 29 Sep, 2019 Expired
US6403609 Ophthalmic compositions containing galactomannan polymers and borate 17 Jul, 2018 Expired
US5607942 7-(1-pyrrolidinyl)-3-quinolone- and - naphthyridone-carboxylic acid derivatives as antibacterial agents and feed additives 04 Sep, 2014 Expired
US5475034 Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders 06 Jun, 2014 Expired
US5607942 7-(1-pyrrolidinyl)-3-quinolone- and - naphthyridone-carboxylic acid derivatives as antibacterial agents and feed additives 04 Mar, 2014 Expired


Given below is the list of recent legal activities going on the following drug patents of Harrow Eye.

Activity Date Patent Number
Patent litigations
Payment of Maintenance Fee, 12th Yr, Small Entity 09 Jun, 2024 US8450287
Payment of Maintenance Fee, 8th Year, Large Entity 09 Jun, 2024 US9662398
Payment of Maintenance Fee, 12th Year, Large Entity 23 Apr, 2024 US8298568
Payment of Maintenance Fee, 4th Year, Large Entity 19 Apr, 2024 US10813976
Payment of Maintenance Fee, 4th Yr, Small Entity 08 Apr, 2024 US10792271
Payment of Maintenance Fee, 12th Yr, Small Entity 17 Dec, 2023 US8324281
Change in Power of Attorney (May Include Associate POA) 12 Dec, 2023 US8450287
Change in Power of Attorney (May Include Associate POA) 12 Dec, 2023 US7795316
Change in Power of Attorney (May Include Associate POA) 12 Dec, 2023 US8101582
Email Notification 12 Dec, 2023 US8101582
Email Notification 12 Dec, 2023 US7795316
Email Notification 12 Dec, 2023 US8450287
Applicant Has Filed a Verified Statement of Small Entity Status in Compliance with 37 CFR 1.27 04 Dec, 2023 US8324281
Payment of Maintenance Fee, 12th Yr, Small Entity 16 Oct, 2023 US8211880
Applicant Has Filed a Verified Statement of Small Entity Status in Compliance with 37 CFR 1.27 16 Oct, 2023 US8211880


Harrow Eye's Drug Patent Litigations

Harrow Eye's drugs have been subject to various legal proceedings, including patent litigations. The earliest legal proceeding was initiated on Oct 12, 2012, against patent number US7671070. The petitioner Apotex Inc., challenged the validity of this patent, with Alcon as the respondent. Click below to track the latest information on how companies are challenging Harrow Eye's patents.

Patent Proceeding Filing Date Status Respondent Petitioner
Patent litigations
US6716830 October, 2012 Terminated-Settled
(15 Nov, 2013)
Alcon Pharmaceuticals Ltd. Apotex Inc.
US7671070 October, 2012 Terminated-Settled
(15 Nov, 2013)
Alcon Apotex Inc.


Harrow Eye Drug Patents' Oppositions Filed in EPO

Harrow Eye drug patents have faced multiple oppositions in the European Patent Office. The earliest opposition was filed on Jan 04, 2017, by Reckitt Benckiser (Brands) Limited. This opposition was filed on patent number EP12173896A. Click below to reveal the latest opposition data.


Application Filing Date Opposition Party Legal Status
Patent litigations
EP12173896A Jan, 2017 Reckitt Benckiser (Brands) Limited Revoked


Harrow Eye's Family Patents

Harrow Eye drugs have patent protection in a total of 42 countries. It's US patent count contributes only to 17.8% of its total global patent coverage. 3 countries have all of their patents expired or invalidated which has opened up potential generic launch opportunities in these countries. Click below to unlock the full patent family tree.

Family Patents



Harrow Eye Drug List

Given below is the complete list of Harrow Eye's drugs and the patents protecting them.


1. Iheezo

Iheezo is protected by 1 patent, which is still active. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US10792271 Topical formulations of chloroprocaine and methods of using same 15 Sep, 2038
(13 years from now)
Active

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Iheezo's drug page


2. Ilevro

Ilevro is protected by 5 patents, out of which 3 have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US8921337 Carboxyvinyl polymer-containing nanoparticle suspensions 31 Mar, 2032
(7 years from now)
Active
US9662398 Carboxylvinyl polymer-containing nanoparticle suspensions 01 Dec, 2030
(6 years from now)
Active
US7947295 Ophthalmic compositions containing a synergistic combination of two polymers 08 Jun, 2024
(5 months ago)
Expired
US6403609 Ophthalmic compositions containing galactomannan polymers and borate 17 Jul, 2018
(6 years ago)
Expired
US5475034 Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders 06 Jun, 2014
(10 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Ilevro's drug page


3. Moxeza

Moxeza is protected by 8 patents, out of which 6 have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US8450311 Pharmaceutical compositions containing a fluoroquinolone antibiotic drug 29 May, 2029
(4 years from now)
Active
US9114168 Pharmaceutical compositions containing a fluoroquinolone antibiotic drug 29 May, 2029
(4 years from now)
Active
US6716830
(Pediatric)
Ophthalmic antibiotic compositions containing moxifloxacin 29 Mar, 2020
(4 years ago)
Expired
US7671070
(Pediatric)
Method of treating ophthalmic infections with moxifloxacin compositions 29 Mar, 2020
(4 years ago)
Expired
US6716830 Ophthalmic antibiotic compositions containing moxifloxacin 29 Sep, 2019
(5 years ago)
Expired
US7671070 Method of treating ophthalmic infections with moxifloxacin compositions 29 Sep, 2019
(5 years ago)
Expired
US5607942
(Pediatric)
7-(1-pyrrolidinyl)-3-quinolone- and - naphthyridone-carboxylic acid derivatives as antibacterial agents and feed additives 04 Sep, 2014
(10 years ago)
Expired
US5607942 7-(1-pyrrolidinyl)-3-quinolone- and - naphthyridone-carboxylic acid derivatives as antibacterial agents and feed additives 04 Mar, 2014
(10 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Moxeza's drug page


4. Nevanac

Nevanac is protected by 4 patents, out of which 1 has expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US7834059 Topical nepafenac formulations 31 Jan, 2027
(2 years from now)
Active
US8071648 Topical nepafenac formulations 02 Dec, 2025
(1 year, 16 days from now)
Active
US8324281 Topical nepafenac formulations 02 Dec, 2025
(1 year, 16 days from now)
Active
US5475034 Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders 06 Jun, 2014
(10 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Nevanac's drug page


5. Tobradex St

Tobradex St is protected by 3 patents, out of which none have expired yet. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US7795316 Topical ophthalmic compositions containing tobramycin and dexamethasone 03 Aug, 2028
(3 years from now)
Active
US8101582 Topical ophthalmic compositions containing tobramycin and dexamethasone 19 Dec, 2027
(3 years from now)
Active
US8450287 Topical ophthalmic compositions containing tobramycin and dexamethasone 19 Dec, 2027
(3 years from now)
Active

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Tobradex St's drug page


Explore Our Curated Drug Screens

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View List
NCE-1 Patent Expiry in the Next 1 Year
Identify opportunities as new chemical entity (NCE-1) patents approach expiry
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Recently Granted Patents in EP
Find the opportunity to file Oppositions
View List

6. Triesence

Triesence is protected by 3 patents, out of which 1 has expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US8128960 Low viscosity, highly flocculated triamcinolone acetonide suspensions for intravitreal injection 17 Dec, 2029
(5 years from now)
Active
US8211880 Low viscosity, highly flocculated triamcinolone acetonide suspensions for intravitreal injection 10 Mar, 2029
(4 years from now)
Active
US6395294 Method of visualization of the vitreous during vitrectomy 13 Jan, 2020
(4 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Triesence's drug page


7. Verkazia

Verkazia is protected by 7 patents, out of which none have expired yet. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US9132071 Compositions containing quaternary ammonium compounds 02 Jun, 2029
(4 years from now)
Active
US8298568 Oil-in-water type emulsion with low concentration of cationic agent and positive zeta potential 03 Nov, 2027
(2 years from now)
Active
US11612658 Oil-in-water emulsions comprising cetalkonium chloride and methods of making and using the same 27 Jan, 2026
(1 year, 2 months from now)
Active
US7973081 Emulsion compositions containing quaternary ammonium compounds 27 Jan, 2026
(1 year, 2 months from now)
Active
US8524779 Emulsion compositions containing quaternary ammonium compounds 27 Jan, 2026
(1 year, 2 months from now)
Active
US9220694 Emulsion compositions containing cetalkonium chloride 27 Jan, 2026
(1 year, 2 months from now)
Active
US9956289 Emulsion compositions containing quaternary ammonium compounds 27 Jan, 2026
(1 year, 2 months from now)
Active

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Verkazia's drug page


8. Vevye

Vevye is protected by 5 patents, out of which none have expired yet. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US12059449 Ophthalmic composition for treatment of dry eye disease 01 Apr, 2042
(17 years from now)
Active
US11413323 Ophthalmic composition for treatment of dry eye disease 11 Oct, 2039
(14 years from now)
Active
US11154513 Semifluorinated compounds 20 Nov, 2038
(14 years from now)
Active
US10813976 Ophthalmic compositions comprising ciclosporin 22 Sep, 2037
(12 years from now)
Active
US8614178 Pharmaceutical composition for treatment of dry eye syndrome 13 Dec, 2030
(6 years from now)
Active

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Vevye's drug page


9. Vigamox

Vigamox is protected by 6 patents, out of which all have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US6716830
(Pediatric)
Ophthalmic antibiotic compositions containing moxifloxacin 29 Mar, 2020
(4 years ago)
Expired
US7671070
(Pediatric)
Method of treating ophthalmic infections with moxifloxacin compositions 29 Mar, 2020
(4 years ago)
Expired
US6716830 Ophthalmic antibiotic compositions containing moxifloxacin 29 Sep, 2019
(5 years ago)
Expired
US7671070 Method of treating ophthalmic infections with moxifloxacin compositions 29 Sep, 2019
(5 years ago)
Expired
US5607942
(Pediatric)
7-(1-pyrrolidinyl)-3-quinolone- and - naphthyridone-carboxylic acid derivatives as antibacterial agents and feed additives 04 Sep, 2014
(10 years ago)
Expired
US5607942 7-(1-pyrrolidinyl)-3-quinolone- and - naphthyridone-carboxylic acid derivatives as antibacterial agents and feed additives 04 Mar, 2014
(10 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Vigamox's drug page


10. Zerviate

Zerviate is protected by 6 patents, out of which none have expired yet. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US9254286
(Pediatric)
Ophthalmic formulations of cetirizine and methods of use 09 Jan, 2033
(8 years from now)
Active
US9254286 Ophthalmic formulations of cetirizine and methods of use 09 Jul, 2032
(7 years from now)
Active
US8829005
(Pediatric)
Ophthalmic formulations of cetirizine and methods of use 15 Sep, 2030
(5 years from now)
Active
US8829005 Ophthalmic formulations of cetirizine and methods of use 15 Mar, 2030
(5 years from now)
Active
US9750684 Ophthalmic formulations of cetirizine and methods of use 15 Mar, 2030
(5 years from now)
Active
US9993471 Ophthalmic formulations of cetirizine and methods of use 15 Mar, 2030
(5 years from now)
Active

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Zerviate's drug page