Bayer Hlthcare Drug Patent Portfolio

Bayer Hlthcare owns 27 orange book drugs protected by 86 US patents with Climara Pro having the least patent protection, holding only 1 patent. And Vitrakvi with maximum patent protection, holding 13 patents. Given below is the list of Bayer Hlthcare's drug patents along with their expiration dates.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US10799505 Crystalline form of (S)-N-(5-((R)-2-(2,5-difluorophenyl)-pyrrolidin-1-yl)-pyrazolo[1,5-A]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate 15 Aug, 2036
Active
US10172861 Crystalline form of (S)-N-(5-((R)-2-(2,5-difluorophenyl)-pyrrolidin-1-yl)-pyrazolo[1,5-A]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate 16 Nov, 2035
Active
US10285993 Crystalline form of (S)-N-(5-((R)-2-(2,5-difluorophenyl)-pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate 16 Nov, 2035
Active
US10813936 Crystalline form of (S)-N-(5-((R)-2-(2,5-difluorophenyl)-pyrrolidin-1-YL)-pyrazolo[1,5-A]pyrimidin-3-YL)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate 16 Nov, 2035
Active
US9782414 Crystalline form of (S)-N-(5-((R)-2-(2,5-difluorophenyl)-pyrrolidin-1-yl)-pyrazolo[1,5-A]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate 16 Nov, 2035
Active
USRE49826 Method for the preparation of (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1-6-naphthyridine-3-carboxamide and the purification thereof for use as an active pharmaceutical ingredient 29 Jul, 2035
Active
US10662188 Forms of methyl {4,6-diamino-2-[1 (2-fluorobenzyl)-1H-pyrazolo[3-4-b]pyridino-3-yl]pyrimidino-5-yl} methyl carbamate 18 Feb, 2034
Active
US11203593 Forms of methyl {4,6-diamino-2-[1(2-fluorobenzyl)-1H-pyrazolo[3-4-b]pyridino-3-yl]pyrimidino-5-yl}methyl carbamate 18 Feb, 2034
Active
US9957232 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide monohydrate 09 Jul, 2032
Active
US8906890 Very low-dosed solid oral dosage forms for HRT 22 Oct, 2031
Active
US9458107 Process for the preparation of 4-{4-[({[4 chloro-3-(trifluoromethyl)-phenyl]amino}carbonyl)amino]-3-fluorphenoxy-N-ethylpyridie-carboxamide, its salts and monohydrate 08 Apr, 2031
Active
US10987244 Inserter 01 Apr, 2031
Active
US9668912 Inserter 01 Apr, 2031
Active
US8637553 Fluoro substituted omega-carboxyaryl diphenyl urea for the treatment and prevention of diseases and conditions 16 Feb, 2031
Active
US11617751 Pharmaceutical composition containing a tetrahydrofolic acid 17 Jul, 2030
Active
US8680124 Treatment of cancers with acquired resistance to kit inhibitors 02 Jun, 2030
Active
US8617597 Pharmaceutical composition containing a tetrahydrofolic acid 08 Feb, 2030
Active
US8513263 Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors 23 Dec, 2029
Active
US10005783 Method of treatment using substituted pyrazolo[1,5-a] pyrimidine compounds 21 Oct, 2029
Active
US10047097 Method of treatment using substituted pyrazolo[1,5-a] pyrimidine compounds 21 Oct, 2029
Active
US10774085 Method of treatment using substituted pyrazolo[1,5-A] pyrimidine compounds 21 Oct, 2029
Active
US8865698 Method of treatment using substituted pyrazolo[1,5-a]pyrimidine compounds 21 Oct, 2029
Active
US9127013 Method of treatment using substituted pyrazolo[1,5-a] pyrimidine compounds 21 Oct, 2029
Active
US9447104 Method of treatment using substituted pyrazolo[1,5-a]pyrimidine compounds 21 Oct, 2029
Active
US9676783 Method of treatment using substituted pyrazolo[1,5-A] pyrimidine compounds 21 Oct, 2029
Active
US10561524 Inserter 16 Sep, 2029
Active
US9615965 Inserter 16 Sep, 2029
Active
US11850182 Inserter 14 Sep, 2029
Active
US8436180 Substituted-4-aryl-1,4-dihydro-1,6-naphthyridinamides and use thereof 12 Apr, 2029
Active
US8613950 Pharmaceutical forms with improved pharmacokinetic properties 23 Dec, 2028
Active
US9737488 Pharmaceutical composition for the treatment of cancer 10 Sep, 2028
Active
US8071073 Compositions comprising azelastine and methods of use thereof 04 Jun, 2028
Active
US8153616 Combination preparation for oral contraception and oral therapy of dysfunctional uterine bleeding containing estradiol valerate and dienogest and method of using same 30 Jan, 2028
Active
US8877933 Thermodynamically stable form of a tosylate salt 24 Dec, 2027
Active
US8273876 Medicaments containing vardenafil hydrochloride trihydrate 23 Jul, 2027
Active
US8791127 Mucosal bioadhesive slow release carrier for delivering active principles 23 Mar, 2027
Active
US11628088 Ultrasonically detectable intrauterine system and a method for enhancing ultrasound detection 07 Feb, 2027
Active
US7173037 Carbamate-substituted pyrazolopyridines 04 Dec, 2026
Active
US8071577 Multi-phase contraceptive preparation based on a natural estrogen 13 May, 2026
Active
US8518919 Compositions comprising azelastine and methods of use thereof 22 Nov, 2025
Active
US9919050 Compositions comprising azelastine 22 Nov, 2025
Active
US7252839 Delivery system and a manufacturing process of a delivery system 13 Nov, 2023 Expired
US8841446 Medicaments containing vardenafil hydrochloride trihydrate 03 Jul, 2023 Expired
US8618141 Aryl ureas with angiogenesis inhibiting activity 11 Feb, 2023 Expired
US7709022 Sustained-release preparations of quinolone antibiotics and method for preparation thereof 23 Dec, 2021 Expired
US8187632 Sustained-release preparations of quinolone antibiotics 23 Dec, 2021 Expired
US6958326 Cyclodextrin-drospirenone inclusion complexes 20 Dec, 2021 Expired
US7163931 Compositions of estrogen-cyclodextrin complexes 20 Dec, 2021 Expired
US6039931 Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production 13 Nov, 2021 Expired
US5980864 1,4,7,10-tetraazacyclododecane butyltriols, processes for their production and pharmaceutical agents containing them 09 Nov, 2021 Expired
US7709022 Sustained-release preparations of quinolone antibiotics and method for preparation thereof 23 Jun, 2021 Expired
US8187632 Sustained-release preparations of quinolone antibiotics 23 Jun, 2021 Expired
US6787531 Pharmaceutical composition for use as a contraceptive 31 Aug, 2020 Expired
US6548079 Moxifloxacin formulation containing common salt 25 Jul, 2020 Expired
US6441168 Stable crystalline salts of 5-methyltetrahydrofolic acid 17 Apr, 2020 Expired
US7235576 Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors 12 Jan, 2020 Expired
US7351834 ω-Carboxyaryl substituted diphenyl ureas as raf kinase inhibitors 12 Jan, 2020 Expired
US7897623 ω-carboxyl aryl substituted diphenyl ureas as p38 kinase inhibitors 12 Jan, 2020 Expired
US8124630 ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors 12 Jan, 2020 Expired
US8841330 Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors 12 Jan, 2020 Expired
US6635234 Preparation and use of radium-223 to target calcified tissues for pain palliation, bone cancer therapy, and bone surface conditioning 03 Jan, 2020 Expired
US6610327 Pharmaceutical moxifloxacin preparation 29 Oct, 2019 Expired
US6743798 Substituted pyrazole derivatives condensed with six-membered heterocyclic rings 16 Jul, 2019 Expired
US6362178 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors 31 Oct, 2018 Expired
US7696206 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors 31 Oct, 2018 Expired
US6987101 Therapeutic gestagens for the treatment of premenstrual dysphoric disorder 22 Dec, 2017 Expired
US5891868 Methods for treating postmenopausal women using ultra-low doses of estrogen 21 Nov, 2017 Expired
US6692763 Methods for treating postmenopausal women using ultra-low doses of estrogen 21 Nov, 2017 Expired
US6933395 PROCESSING FOR PRODUCING OF DROSPIRENONE (6β, 7β, 15β, 16β-DIMETHYLENE-3-OXO-17α-PREGN-4-EN-21, 17-CARBOLACTONE, DRSP) AS WELL AS 7α-(3-HYDOXY-1-PROPLY)-6β, 7β; 15β, 16β-DIMETHYLENE-5β-ANDROSTANE-3β, 5,17β-TRIOL(ZK 92836) AND 6β, 7β; 15β, 16β-DIMETHYLENE-5β-HYDROXY 11 Aug, 2017 Expired
US5849752 Crystal modification of CDCH a process for its preparation and pharmaceutical formulations comprising this modification 05 Dec, 2016 Expired
US6133251 Combination compound for contraception based on natural estrogen 25 Oct, 2016 Expired
US6884793 Combination preparation for contraception based on natural estrogens 25 Oct, 2016 Expired
US5785053 Inserter for the positioning of an intrauterine device 05 Dec, 2015 Expired
US5798092 Derivatized DTPA complexes pharmaceutical agents containing these compounds, their use, and processes for their production 25 Aug, 2015 Expired
US5798338 Solid dosage forms that contain clathrates of 17α-ethinyl estradiol 10 Jul, 2015 Expired
US5695784 Flavor-masked pharmaceutical compositions 09 Jun, 2015 Expired
US5695784 Flavor-masked pharmaceutical compositions 09 Dec, 2014 Expired
US5676968 Transdermal therapeutic systems with crystallization inhibitors 14 Oct, 2014 Expired
USRE37564 Composition for contraception 30 Jun, 2014 Expired
USRE37838 Composition for contraception 30 Jun, 2014 Expired
USRE38253 Composition for contraception 30 Jun, 2014 Expired
USRE43916 Composition for contraception 30 Jun, 2014 Expired
US5607942 7-(1-pyrrolidinyl)-3-quinolone- and - naphthyridone-carboxylic acid derivatives as antibacterial agents and feed additives 04 Mar, 2014 Expired
US5569652 Dihydrospirorenone as an antiandrogen 29 Oct, 2013 Expired
US6136347 Flavor-masked pharmaceutical compositions 06 Jul, 2013 Expired
US6136347 Flavor-masked pharmaceutical compositions 06 Jan, 2013 Expired


Given below is the list of recent legal activities going on the following drug patents of Bayer Hlthcare.

Activity Date Patent Number
Patent litigations
Expire Patent 01 Jul, 2024 US8187632
Payment of Maintenance Fee, 4th Year, Large Entity 10 Apr, 2024 US10813936
Expire Patent 01 Apr, 2024 US8124630
Payment of Maintenance Fee, 4th Year, Large Entity 27 Mar, 2024 US10799505
Payment of Maintenance Fee, 8th Year, Large Entity 20 Mar, 2024 US9458107
Payment of Maintenance Fee, 12th Year, Large Entity 14 Mar, 2024 US8273876 (Litigated)
Payment of Maintenance Fee, 8th Year, Large Entity 06 Mar, 2024 US9447104
Payment of Maintenance Fee, 4th Year, Large Entity 28 Feb, 2024 US10774085
Maintenance Fee Reminder Mailed 15 Jan, 2024 US8187632
Patent Issue Date Used in PTA Calculation 26 Dec, 2023 US11850182
Patent eGrant Notification 26 Dec, 2023 US11850182
Patent Issue Date Used in PTA Calculation 26 Dec, 2023 US11850182
Patent eGrant Notification 26 Dec, 2023 US11850182
Mail Patent eGrant Notification 26 Dec, 2023 US11850182
Recordation of Patent eGrant 26 Dec, 2023 US11850182


Bayer Hlthcare's Drug Patent Litigations

Bayer Hlthcare's drugs have been subject to various legal proceedings, including patent litigations. The earliest legal proceeding was initiated on Jun 17, 2005, against patent number US8124630. The petitioner , challenged the validity of this patent, with Bernd Riedl et al as the respondent. Click below to track the latest information on how companies are challenging Bayer Hlthcare's patents.

Patent Proceeding Filing Date Status Respondent Petitioner
Patent litigations
US9957232 November, 2015 Decision
(14 Feb, 2017)
Alfons Grunenberg et al
US8637553 July, 2016 Terminated-Denied
(08 Feb, 2017)
Bayer HealthCare LLC Fustibal LLC
US8071073 May, 2014 Terminated-Denied
(29 Jul, 2014)
Meda Pharmaceuticals Inc. Impax Laboratories, Inc.
US8187632 June, 2010 Decision
(08 Nov, 2011)
Venkata-Rangarao Kanikanti et al
US8124630 June, 2005 Decision
(27 Dec, 2005)
Bernd Riedl et al


Bayer Hlthcare Drug Patents' Oppositions Filed in EPO

Bayer Hlthcare drug patents have faced multiple oppositions in the European Patent Office. The earliest opposition was filed on Dec 03, 2008, by N.V. Organon. This opposition was filed on patent number EP03797325A. Click below to reveal the latest opposition data.


Application Filing Date Opposition Party Legal Status
Patent litigations
EP10183693A Jul, 2017 Accord Healthcare Ltd Opposition rejected
EP10183693A Jul, 2017 Teva Pharmaceutical Industries Ltd Opposition rejected
EP10183693A Jul, 2017 Zentiva k.s. Opposition rejected
EP03707846A Apr, 2014 Accord Healthcare Ltd Revoked
EP03707846A Apr, 2014 Hetero Drugs Ltd. Revoked
EP07818583A Mar, 2014 Fresenius Kabi Deutschland GmbH Opposition rejected
EP09736608A Feb, 2014 Actavis Group PTC ehf Patent maintained as amended
EP09736244A Sep, 2013 Actavis Group PTC EHF Patent maintained as amended
EP05797740A Mar, 2013 Biofer S.p.A. Revoked
EP05797740A Mar, 2013 Fresenius Kabi Deutschland GmbH Revoked
EP06706994A Jan, 2013 Generics [UK] Limited Opposition rejected
EP06706994A Jan, 2013 Accord Healthcare Ltd Opposition rejected
EP03763695A Sep, 2012 Accord Healthcare Ltd Revoked
EP03763695A Sep, 2012 Zentiva k.s. Revoked
EP06707141A Jun, 2011 Teva Pharmaceutical Industries Ltd. Revoked
EP06707141A Jun, 2011 Altmann, Andreas Revoked
EP05730867A Apr, 2011 Lupin Limited Patent maintained as amended
EP05730867A Apr, 2011 Laboratorios Léon Farma, S.A. Patent maintained as amended
EP05022324A Nov, 2009 Sandoz International GmbH Revoked
EP03797325A Dec, 2008 N.V. Organon Patent maintained as amended


Bayer Hlthcare's Family Patents

Bayer Hlthcare drugs have patent protection in a total of 64 countries. It's US patent count contributes only to 12.5% of its total global patent coverage. 11 countries have all of their patents expired or invalidated which has opened up potential generic launch opportunities in these countries. Click below to unlock the full patent family tree.

Family Patents



Bayer Hlthcare Drug List

Given below is the complete list of Bayer Hlthcare's drugs and the patents protecting them.


1. Adempas

Adempas is protected by 4 patents, out of which 1 has expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US10662188 Forms of methyl {4,6-diamino-2-[1 (2-fluorobenzyl)-1H-pyrazolo[3-4-b]pyridino-3-yl]pyrimidino-5-yl} methyl carbamate 18 Feb, 2034
(9 years from now)
Active
US11203593 Forms of methyl {4,6-diamino-2-[1(2-fluorobenzyl)-1H-pyrazolo[3-4-b]pyridino-3-yl]pyrimidino-5-yl}methyl carbamate 18 Feb, 2034
(9 years from now)
Active
US7173037 Carbamate-substituted pyrazolopyridines 04 Dec, 2026
(2 years from now)
Active
US6743798 Substituted pyrazole derivatives condensed with six-membered heterocyclic rings 16 Jul, 2019
(5 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Adempas's drug page


2. Angeliq

Angeliq is protected by 2 patents, out of which 1 has expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US8906890 Very low-dosed solid oral dosage forms for HRT 22 Oct, 2031
(7 years from now)
Active
US6933395 PROCESSING FOR PRODUCING OF DROSPIRENONE (6β, 7β, 15β, 16β-DIMETHYLENE-3-OXO-17α-PREGN-4-EN-21, 17-CARBOLACTONE, DRSP) AS WELL AS 7α-(3-HYDOXY-1-PROPLY)-6β, 7β; 15β, 16β-DIMETHYLENE-5β-ANDROSTANE-3β, 5,17β-TRIOL(ZK 92836) AND 6β, 7β; 15β, 16β-DIMETHYLENE-5β-HYDROXY 11 Aug, 2017
(7 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Angeliq's drug page


3. Astepro Allergy

Astepro Allergy is protected by 3 patents, out of which none have expired yet. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US8071073 Compositions comprising azelastine and methods of use thereof 04 Jun, 2028
(3 years from now)
Active
US8518919 Compositions comprising azelastine and methods of use thereof 22 Nov, 2025
(1 year, 1 month from now)
Active
US9919050 Compositions comprising azelastine 22 Nov, 2025
(1 year, 1 month from now)
Active

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Astepro Allergy's drug page


4. Avelox

Avelox is protected by 3 patents, out of which all have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US6610327 Pharmaceutical moxifloxacin preparation 29 Oct, 2019
(4 years ago)
Expired
US5849752 Crystal modification of CDCH a process for its preparation and pharmaceutical formulations comprising this modification 05 Dec, 2016
(7 years ago)
Expired
US5607942 7-(1-pyrrolidinyl)-3-quinolone- and - naphthyridone-carboxylic acid derivatives as antibacterial agents and feed additives 04 Mar, 2014
(10 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Avelox's drug page


5. Avelox In Sodium Chloride 0.8% In Plastic Container

Avelox In Sodium Chloride 0.8% In Plastic Container is protected by 3 patents, out of which all have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US6548079 Moxifloxacin formulation containing common salt 25 Jul, 2020
(4 years ago)
Expired
US5849752 Crystal modification of CDCH a process for its preparation and pharmaceutical formulations comprising this modification 05 Dec, 2016
(7 years ago)
Expired
US5607942 7-(1-pyrrolidinyl)-3-quinolone- and - naphthyridone-carboxylic acid derivatives as antibacterial agents and feed additives 04 Mar, 2014
(10 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Avelox In Sodium Chloride 0.8% In Plastic Container's drug page


Explore Our Curated Drug Screens

Drugs Generating Over $1 Billion in Annual Revenue
Explore the top-performing drugs that dominate the pharmaceutical industry
View List
NCE-1 Patent Expiry in the Next 1 Year
Identify opportunities as new chemical entity (NCE-1) patents approach expiry
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Recently Granted Patents in EP
Find the opportunity to file Oppositions
View List

6. Beyaz

Beyaz is protected by 10 patents, out of which 8 have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US11617751 Pharmaceutical composition containing a tetrahydrofolic acid 17 Jul, 2030
(5 years from now)
Active
US8617597 Pharmaceutical composition containing a tetrahydrofolic acid 08 Feb, 2030
(5 years from now)
Active
US7163931 Compositions of estrogen-cyclodextrin complexes 03 Mar, 2022
(2 years ago)
Expired
US6958326 Cyclodextrin-drospirenone inclusion complexes 30 Dec, 2021
(2 years ago)
Expired
US6441168 Stable crystalline salts of 5-methyltetrahydrofolic acid 17 Apr, 2020
(4 years ago)
Expired
US5798338 Solid dosage forms that contain clathrates of 17α-ethinyl estradiol 10 Jul, 2015
(9 years ago)
Expired
USRE37564 Composition for contraception 30 Jun, 2014
(10 years ago)
Expired
USRE37838 Composition for contraception 30 Jun, 2014
(10 years ago)
Expired
USRE38253 Composition for contraception 30 Jun, 2014
(10 years ago)
Expired
USRE43916 Composition for contraception 30 Jun, 2014
(10 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Beyaz's drug page


7. Children's Astepro Allergy

Children's Astepro Allergy is protected by 3 patents, out of which none have expired yet. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US8071073 Compositions comprising azelastine and methods of use thereof 04 Jun, 2028
(3 years from now)
Active
US8518919 Compositions comprising azelastine and methods of use thereof 22 Nov, 2025
(1 year, 1 month from now)
Active
US9919050 Compositions comprising azelastine 22 Nov, 2025
(1 year, 1 month from now)
Active

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Children's Astepro Allergy's drug page


8. Cipro

Cipro is protected by 4 patents, out of which all have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US5695784
(Pediatric)
Flavor-masked pharmaceutical compositions 09 Jun, 2015
(9 years ago)
Expired
US5695784 Flavor-masked pharmaceutical compositions 09 Dec, 2014
(9 years ago)
Expired
US6136347
(Pediatric)
Flavor-masked pharmaceutical compositions 06 Jul, 2013
(11 years ago)
Expired
US6136347 Flavor-masked pharmaceutical compositions 06 Jan, 2013
(11 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Cipro's drug page


9. Cipro Xr

Cipro Xr is protected by 4 patents, out of which all have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US7709022
(Pediatric)
Sustained-release preparations of quinolone antibiotics and method for preparation thereof 23 Dec, 2021
(2 years ago)
Expired
US8187632
(Pediatric)
Sustained-release preparations of quinolone antibiotics 23 Dec, 2021
(2 years ago)
Expired
US7709022 Sustained-release preparations of quinolone antibiotics and method for preparation thereof 23 Jun, 2021
(3 years ago)
Expired
US8187632 Sustained-release preparations of quinolone antibiotics 23 Jun, 2021
(3 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Cipro Xr's drug page


10. Climara Pro

Climara Pro is protected by 1 patent, which has expired already. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US5676968 Transdermal therapeutic systems with crystallization inhibitors 14 Oct, 2014
(9 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Climara Pro's drug page


11. Eovist

Eovist is protected by 2 patents, out of which all have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US6039931 Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production 13 Nov, 2021
(2 years ago)
Expired
US5798092 Derivatized DTPA complexes pharmaceutical agents containing these compounds, their use, and processes for their production 25 Aug, 2015
(9 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Eovist's drug page


12. Gadavist

Gadavist is protected by 2 patents, out of which all have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US5980864 1,4,7,10-tetraazacyclododecane butyltriols, processes for their production and pharmaceutical agents containing them 09 Nov, 2021
(2 years ago)
Expired
US5980864 1,4,7,10-tetraazacyclododecane butyltriols, processes for their production and pharmaceutical agents containing them 09 Nov, 2016
(7 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Gadavist's drug page


13. Kerendia

Kerendia is protected by 2 patents, out of which none have expired yet. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
USRE49826 Method for the preparation of (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1-6-naphthyridine-3-carboxamide and the purification thereof for use as an active pharmaceutical ingredient 29 Jul, 2035
(10 years from now)
Active
US8436180 Substituted-4-aryl-1,4-dihydro-1,6-naphthyridinamides and use thereof 12 Apr, 2029
(4 years from now)
Active

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Kerendia's drug page


14. Kyleena

Kyleena is protected by 7 patents, out of which 1 has expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US10987244 Inserter 01 Apr, 2031
(6 years from now)
Active
US9668912 Inserter 01 Apr, 2031
(6 years from now)
Active
US10561524 Inserter 16 Sep, 2029
(4 years from now)
Active
US9615965 Inserter 16 Sep, 2029
(4 years from now)
Active
US11850182 Inserter 14 Sep, 2029
(4 years from now)
Active
US11628088 Ultrasonically detectable intrauterine system and a method for enhancing ultrasound detection 07 Feb, 2027
(2 years from now)
Active
US7252839 Delivery system and a manufacturing process of a delivery system 13 Nov, 2023
(10 months ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Kyleena's drug page


15. Levitra

Levitra is protected by 4 patents, out of which 3 have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US8273876 Medicaments containing vardenafil hydrochloride trihydrate 23 Jul, 2027
(2 years from now)
Active
US8841446 Medicaments containing vardenafil hydrochloride trihydrate 03 Jul, 2023
(1 year, 3 months ago)
Expired
US6362178 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors 31 Oct, 2018
(5 years ago)
Expired
US7696206 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors 31 Oct, 2018
(5 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Levitra's drug page


16. Menostar

Menostar is protected by 2 patents, out of which all have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US5891868 Methods for treating postmenopausal women using ultra-low doses of estrogen 21 Nov, 2017
(6 years ago)
Expired
US6692763 Methods for treating postmenopausal women using ultra-low doses of estrogen 21 Nov, 2017
(6 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Menostar's drug page


17. Mirena

Mirena is protected by 6 patents, out of which 1 has expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US10987244 Inserter 01 Apr, 2031
(6 years from now)
Active
US9668912 Inserter 01 Apr, 2031
(6 years from now)
Active
US10561524 Inserter 16 Sep, 2029
(4 years from now)
Active
US9615965 Inserter 16 Sep, 2029
(4 years from now)
Active
US11850182 Inserter 14 Sep, 2029
(4 years from now)
Active
US5785053 Inserter for the positioning of an intrauterine device 05 Dec, 2015
(8 years ago)
Expired

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18. Natazia

Natazia is protected by 4 patents, out of which 2 have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US8153616 Combination preparation for oral contraception and oral therapy of dysfunctional uterine bleeding containing estradiol valerate and dienogest and method of using same 30 Jan, 2028
(3 years from now)
Active
US8071577 Multi-phase contraceptive preparation based on a natural estrogen 13 May, 2026
(1 year, 7 months from now)
Active
US6133251 Combination compound for contraception based on natural estrogen 25 Oct, 2016
(7 years ago)
Expired
US6884793 Combination preparation for contraception based on natural estrogens 25 Oct, 2016
(7 years ago)
Expired

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19. Nexavar

Nexavar is protected by 8 patents, out of which 6 have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US9737488 Pharmaceutical composition for the treatment of cancer 10 Sep, 2028
(3 years from now)
Active
US8877933 Thermodynamically stable form of a tosylate salt 24 Dec, 2027
(3 years from now)
Active
US8618141 Aryl ureas with angiogenesis inhibiting activity 11 Feb, 2023
(1 year, 7 months ago)
Expired
US7235576 Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors 12 Jan, 2020
(4 years ago)
Expired
US7351834 ω-Carboxyaryl substituted diphenyl ureas as raf kinase inhibitors 12 Jan, 2020
(4 years ago)
Expired
US7897623 ω-carboxyl aryl substituted diphenyl ureas as p38 kinase inhibitors 12 Jan, 2020
(4 years ago)
Expired
US8124630 ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors 12 Jan, 2020
(4 years ago)
Expired
US8841330 Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors 12 Jan, 2020
(4 years ago)
Expired

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20. Safyral

Safyral is protected by 6 patents, out of which 4 have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US11617751 Pharmaceutical composition containing a tetrahydrofolic acid 17 Jul, 2030
(5 years from now)
Active
US8617597 Pharmaceutical composition containing a tetrahydrofolic acid 08 Feb, 2030
(5 years from now)
Active
US7163931 Compositions of estrogen-cyclodextrin complexes 03 Mar, 2022
(2 years ago)
Expired
US6958326 Cyclodextrin-drospirenone inclusion complexes 20 Dec, 2021
(2 years ago)
Expired
US6441168 Stable crystalline salts of 5-methyltetrahydrofolic acid 17 Apr, 2020
(4 years ago)
Expired
US5798338 Solid dosage forms that contain clathrates of 17α-ethinyl estradiol 10 Jul, 2015
(9 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Safyral's drug page


21. Skyla

Skyla is protected by 8 patents, out of which 2 have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US10987244 Inserter 01 Apr, 2031
(6 years from now)
Active
US9668912 Inserter 01 Apr, 2031
(6 years from now)
Active
US10561524 Inserter 16 Sep, 2029
(4 years from now)
Active
US9615965 Inserter 16 Sep, 2029
(4 years from now)
Active
US11850182 Inserter 14 Sep, 2029
(4 years from now)
Active
US11628088 Ultrasonically detectable intrauterine system and a method for enhancing ultrasound detection 07 Feb, 2027
(2 years from now)
Active
US7252839 Delivery system and a manufacturing process of a delivery system 13 Nov, 2023
(10 months ago)
Expired
US5785053 Inserter for the positioning of an intrauterine device 05 Dec, 2015
(8 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Skyla's drug page


22. Staxyn

Staxyn is protected by 3 patents, out of which 2 have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US8613950 Pharmaceutical forms with improved pharmacokinetic properties 23 Dec, 2028
(4 years from now)
Active
US6362178 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors 31 Oct, 2018
(5 years ago)
Expired
US7696206 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors 31 Oct, 2018
(5 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Staxyn's drug page


23. Stivarga

Stivarga is protected by 5 patents, out of which 1 has expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US9957232 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide monohydrate 09 Jul, 2032
(7 years from now)
Active
US9458107 Process for the preparation of 4-{4-[({[4 chloro-3-(trifluoromethyl)-phenyl]amino}carbonyl)amino]-3-fluorphenoxy-N-ethylpyridie-carboxamide, its salts and monohydrate 08 Apr, 2031
(6 years from now)
Active
US8637553 Fluoro substituted omega-carboxyaryl diphenyl urea for the treatment and prevention of diseases and conditions 16 Feb, 2031
(6 years from now)
Active
US8680124 Treatment of cancers with acquired resistance to kit inhibitors 02 Jun, 2030
(5 years from now)
Active
US7351834 ω-Carboxyaryl substituted diphenyl ureas as raf kinase inhibitors 12 Jan, 2020
(4 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Stivarga's drug page


24. Vitrakvi

Vitrakvi is protected by 13 patents, out of which none have expired yet. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US10799505 Crystalline form of (S)-N-(5-((R)-2-(2,5-difluorophenyl)-pyrrolidin-1-yl)-pyrazolo[1,5-A]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate 15 Aug, 2036
(11 years from now)
Active
US10172861 Crystalline form of (S)-N-(5-((R)-2-(2,5-difluorophenyl)-pyrrolidin-1-yl)-pyrazolo[1,5-A]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate 16 Nov, 2035
(11 years from now)
Active
US10285993 Crystalline form of (S)-N-(5-((R)-2-(2,5-difluorophenyl)-pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate 16 Nov, 2035
(11 years from now)
Active
US10813936 Crystalline form of (S)-N-(5-((R)-2-(2,5-difluorophenyl)-pyrrolidin-1-YL)-pyrazolo[1,5-A]pyrimidin-3-YL)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate 16 Nov, 2035
(11 years from now)
Active
US9782414 Crystalline form of (S)-N-(5-((R)-2-(2,5-difluorophenyl)-pyrrolidin-1-yl)-pyrazolo[1,5-A]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate 16 Nov, 2035
(11 years from now)
Active
US8513263 Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors 23 Dec, 2029
(5 years from now)
Active
US10005783 Method of treatment using substituted pyrazolo[1,5-a] pyrimidine compounds 21 Oct, 2029
(5 years from now)
Active
US10047097 Method of treatment using substituted pyrazolo[1,5-a] pyrimidine compounds 21 Oct, 2029
(5 years from now)
Active
US10774085 Method of treatment using substituted pyrazolo[1,5-A] pyrimidine compounds 21 Oct, 2029
(5 years from now)
Active
US8865698 Method of treatment using substituted pyrazolo[1,5-a]pyrimidine compounds 21 Oct, 2029
(5 years from now)
Active
US9127013 Method of treatment using substituted pyrazolo[1,5-a] pyrimidine compounds 21 Oct, 2029
(5 years from now)
Active
US9447104 Method of treatment using substituted pyrazolo[1,5-a]pyrimidine compounds 21 Oct, 2029
(5 years from now)
Active
US9676783 Method of treatment using substituted pyrazolo[1,5-A] pyrimidine compounds 21 Oct, 2029
(5 years from now)
Active

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Vitrakvi's drug page


25. Xofigo

Xofigo is protected by 2 patents, out of which 1 has expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US8791127 Mucosal bioadhesive slow release carrier for delivering active principles 23 Mar, 2027
(2 years from now)
Active
US6635234 Preparation and use of radium-223 to target calcified tissues for pain palliation, bone cancer therapy, and bone surface conditioning 03 Jan, 2020
(4 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Xofigo's drug page


26. Yasmin

Yasmin is protected by 3 patents, out of which all have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US6787531 Pharmaceutical composition for use as a contraceptive 31 Aug, 2020
(4 years ago)
Expired
US6933395 PROCESSING FOR PRODUCING OF DROSPIRENONE (6β, 7β, 15β, 16β-DIMETHYLENE-3-OXO-17α-PREGN-4-EN-21, 17-CARBOLACTONE, DRSP) AS WELL AS 7α-(3-HYDOXY-1-PROPLY)-6β, 7β; 15β, 16β-DIMETHYLENE-5β-ANDROSTANE-3β, 5,17β-TRIOL(ZK 92836) AND 6β, 7β; 15β, 16β-DIMETHYLENE-5β-HYDROXY 11 Aug, 2017
(7 years ago)
Expired
US5569652 Dihydrospirorenone as an antiandrogen 29 Oct, 2013
(10 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Yasmin's drug page


27. Yaz

Yaz is protected by 11 patents, out of which all have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US6958326 Cyclodextrin-drospirenone inclusion complexes 20 Dec, 2021
(2 years ago)
Expired
US7163931 Compositions of estrogen-cyclodextrin complexes 20 Dec, 2021
(2 years ago)
Expired
US6787531 Pharmaceutical composition for use as a contraceptive 31 Aug, 2020
(4 years ago)
Expired
US6987101 Therapeutic gestagens for the treatment of premenstrual dysphoric disorder 22 Dec, 2017
(6 years ago)
Expired
US6933395 PROCESSING FOR PRODUCING OF DROSPIRENONE (6β, 7β, 15β, 16β-DIMETHYLENE-3-OXO-17α-PREGN-4-EN-21, 17-CARBOLACTONE, DRSP) AS WELL AS 7α-(3-HYDOXY-1-PROPLY)-6β, 7β; 15β, 16β-DIMETHYLENE-5β-ANDROSTANE-3β, 5,17β-TRIOL(ZK 92836) AND 6β, 7β; 15β, 16β-DIMETHYLENE-5β-HYDROXY 11 Aug, 2017
(7 years ago)
Expired
US5798338 Solid dosage forms that contain clathrates of 17α-ethinyl estradiol 10 Jul, 2015
(9 years ago)
Expired
USRE37564 Composition for contraception 30 Jun, 2014
(10 years ago)
Expired
USRE37838 Composition for contraception 30 Jun, 2014
(10 years ago)
Expired
USRE38253 Composition for contraception 30 Jun, 2014
(10 years ago)
Expired
USRE43916 Composition for contraception 30 Jun, 2014
(10 years ago)
Expired
US5569652 Dihydrospirorenone as an antiandrogen 29 Oct, 2013
(10 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Yaz's drug page