Fungal Infections Therapeutics

1. Brexafemme patent expiration

Treatment: Treatment of adult and post-menarchal pediatric females with vulvovaginal candidiasis (vvc); Reduction in the incidence of recurrent vulvovaginal candidiasis (rvvc) in adult and post-menarchal pediatr...

BREXAFEMME's oppositions filed in EPO
Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents protects the active chemical substance. Only drug patent owner can launch products that use this active substance.
US8188085 GLAXOSMITHKLINE Antifungal agents
Aug, 2030

(4 years from now)

US10927142 GLAXOSMITHKLINE Salts and polymorphs of SCY-078
Jan, 2035

(9 years from now)

US10174074 GLAXOSMITHKLINE Salts and polymorphs of SCY-078
Jan, 2035

(9 years from now)

These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US10370406 GLAXOSMITHKLINE Salts and polymorphs of SCY-078
Jan, 2035

(9 years from now)

US11534433 GLAXOSMITHKLINE Antifungal agents with enhanced activity in acidic pH
Jun, 2039

(13 years from now)




Drug Exclusivity Drug Exclusivity Expiration
New Indication(I-903) Nov 30, 2025
New Chemical Entity Exclusivity(NCE) Jun 01, 2026
Generating Antibiotic Incentives Now(GAIN) Jun 01, 2031

Drugs and Companies using IBREXAFUNGERP CITRATE ingredient

NCE-1 date: 01 June, 2030

Market Authorisation Date: 01 June, 2021

Dosage: TABLET

More Information on Dosage

BREXAFEMME family patents

Family Patents

2. Cancidas patent expiration

Treatment: Cancidas is indicated for empirical therapy for presumed fungal infections in febrile, neutropenic patients.

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US5514650 MERCK Aza cyclohexapeptide compounds
Jan, 2015

(10 years ago)

US5792746 MERCK Aza cyclohexapeptide compounds
Mar, 2013

(12 years ago)

US6136783 MERCK Antifungal compositions
Mar, 2017

(8 years ago)

US5792746

(Pediatric)

MERCK Aza cyclohexapeptide compounds
Sep, 2013

(12 years ago)

US5378804

(Pediatric)

MERCK Aza cyclohexapeptide compounds
Sep, 2013

(12 years ago)

US5378804 MERCK Aza cyclohexapeptide compounds
Mar, 2013

(12 years ago)

US5952300 MERCK Antifungal compositions
Mar, 2017

(8 years ago)

US5514650

(Pediatric)

MERCK Aza cyclohexapeptide compounds
Jul, 2015

(10 years ago)

US5952300

(Pediatric)

MERCK Antifungal compositions
Sep, 2017

(8 years ago)

US6136783

(Pediatric)

MERCK Antifungal compositions
Sep, 2017

(8 years ago)




Drugs and Companies using CASPOFUNGIN ACETATE ingredient

Market Authorisation Date: 26 January, 2001

Dosage: POWDER

How can I launch a generic of CANCIDAS before it's drug patent expiration?
More Information on Dosage

CANCIDAS family patents

Family Patents

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3. Cresemba patent expiration

Treatment: NA

CRESEMBA's oppositions filed in EPO
Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents protects the active chemical substance. Only drug patent owner can launch products that use this active substance.
US7459561 ASTELLAS N-substituted carbamoyloxyalkyl-azolium derivatives
Oct, 2020

(5 years ago)

US10812238 ASTELLAS Configurable reference signals
Oct, 2025

(2 months ago)

US6812238 ASTELLAS N-substituted carbamoyloxyalkyl-azolium derivatives
Oct, 2025

(2 months ago)

These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US10603280 ASTELLAS Active ingredient containing stabilised solid medicinal forms and methods for the production thereof
Sep, 2027

(1 year, 8 months from now)

US10206879 ASTELLAS Active ingredient containing stabilised solid forms and method for the production thereof
Sep, 2027

(1 year, 8 months from now)

US6812238

(Pediatric)

ASTELLAS N-substituted carbamoyloxyalkyl-azolium derivatives
Apr, 2026

(3 months from now)

US10603280

(Pediatric)

ASTELLAS Active ingredient containing stabilised solid medicinal forms and methods for the production thereof
Mar, 2028

(2 years from now)

US10206879

(Pediatric)

ASTELLAS Active ingredient containing stabilised solid forms and method for the production thereof
Mar, 2028

(2 years from now)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Mar 06, 2020
Orphan Drug Exclusivity(ODE) Mar 06, 2022
ODE*(ODE*) Mar 06, 2022
Orphan Drug Exclusivity(ODE-305) Mar 06, 2022
Orphan Drug Exclusivity(ODE-90) Mar 06, 2022
New Patient Population(NPP) Dec 08, 2026
Generating Antibiotic Incentives Now(GAIN) Sep 06, 2027
Orphan Drug Exclusivity(ODE-453) Dec 08, 2030
Orphan Drug Exclusivity(ODE-454) Dec 08, 2030
Orphan Drug Exclusivity(ODE-458) Dec 08, 2030
Orphan Drug Exclusivity(ODE-459) Dec 08, 2030
Pediatric Exclusivity(PED) Jun 08, 2031

Drugs and Companies using ISAVUCONAZONIUM SULFATE ingredient

NCE-1 date: 08 June, 2030

Market Authorisation Date: 06 March, 2015

Dosage: POWDER; CAPSULE

More Information on Dosage

CRESEMBA family patents

Family Patents

4. Eraxis patent expiration

Treatment: Treatment of fungal infections

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US5965525 VICURON HOLDINGS Cyclic peptide antifungal agents
Feb, 2020

(5 years ago)

US7709444 VICURON HOLDINGS Echinocandin pharmaceutical formulations containing micelle-forming surfactants
Apr, 2021

(4 years ago)

US6960564 VICURON HOLDINGS Echinocandin pharmaceutical formulations containing micelle-forming surfactants
Apr, 2021

(4 years ago)




Drug Exclusivity Drug Exclusivity Expiration
New Patient Population(NPP) Sep 22, 2023

Drugs and Companies using ANIDULAFUNGIN ingredient

Market Authorisation Date: 17 February, 2006

Dosage: POWDER

More Information on Dosage

ERAXIS family patents

Family Patents

5. Ertaczo patent expiration

Treatment: Product is approved for the topical treatment of tinea pedis

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US5135943 LACER PHARMA 1H-imidazole derivative compounds and pharmaceutical compositions containing the same
May, 2014

(11 years ago)




Drugs and Companies using SERTACONAZOLE NITRATE ingredient

Market Authorisation Date: 10 December, 2003

Dosage: CREAM

More Information on Dosage

ERTACZO family patents

Family Patents

6. Jublia patent expiration

Treatment: Antimycotic uses, specifically treatment of onychomycosis; Topical treatment of onychomycosis of the toenail(s) due to trichophyton rubrum and trichophyton mentagrophytes; Topical treatment of the toe...

JUBLIA IPR and PTAB Proceedings
Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US7214506 BAUSCH Method for treating onychomycosis
Feb, 2026

(a month from now)

US9566272 BAUSCH Compositions and methods for treating diseases of the nail
Jan, 2028

(1 year, 11 months from now)

US9877955 BAUSCH Compositions and methods for treating diseases of the nail
Jan, 2028

(1 year, 11 months from now)

US10512640 BAUSCH Compositions and methods for treating diseases of the nail
Jan, 2028

(1 year, 11 months from now)

US10342875 BAUSCH Stabilized efinaconazole compositions
Oct, 2034

(8 years from now)

US11213519 BAUSCH Compositions and methods for treating diseases of the nail
Jan, 2028

(1 year, 11 months from now)

US10478601 BAUSCH Applicator
Apr, 2035

(9 years from now)

US11654139 BAUSCH Anti-infective methods, compositions, and devices
Oct, 2034

(8 years from now)

US10828293 BAUSCH Anti-infective methods, compositions, and devices
Oct, 2034

(8 years from now)

US10864274 BAUSCH Stabilized efinaconazole formulations
Oct, 2034

(8 years from now)

US11872218 BAUSCH Compositions and methods for treating diseases of the nail
Jan, 2028

(1 year, 11 months from now)

US8039494 BAUSCH Compositions and methods for treating diseases of the nail
Jul, 2030

(4 years from now)

US9662394 BAUSCH Stabilized efinaconazole compositions
Oct, 2034

(8 years from now)

US9861698 BAUSCH Compositions and methods for treating diseases of the nail
Jul, 2030

(4 years from now)

US8486978 BAUSCH Compositions and methods for treating diseases of the nail
Oct, 2030

(4 years from now)

US10105444 BAUSCH Compositions and methods for treating diseases of the nail
Jul, 2030

(4 years from now)

US9302009 BAUSCH Compositions and methods for treating diseases of the nail
Oct, 2030

(4 years from now)

US10828369 BAUSCH Compositions and methods for treating diseases of the nail
Jan, 2028

(1 year, 11 months from now)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Jun 06, 2019
New Patient Population(NPP) Apr 27, 2023

Drugs and Companies using EFINACONAZOLE ingredient

NCE-1 date: 06 June, 2018

Market Authorisation Date: 06 June, 2014

Dosage: SOLUTION

How can I launch a generic of JUBLIA before it's drug patent expiration?
More Information on Dosage

JUBLIA family patents

Family Patents

7. Kerydin patent expiration

Treatment: Treatment for onychomycosis that is tinea unguium; Treatment of onychomychosis of a toenail caused by trichophyton rubrum or trichophyton mentagrophytes; Treatment of onychomycosis of a toenail

KERYDIN IPR and PTAB Proceedings
Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US9566289 ANACOR PHARMS INC Boron-containing small molecules
Feb, 2026

(a month from now)

US7582621 ANACOR PHARMS INC Boron-containing small molecules
May, 2027

(1 year, 4 months from now)

US9566290 ANACOR PHARMS INC Boron-containing small molecules
Feb, 2026

(a month from now)

US9566290

(Pediatric)

ANACOR PHARMS INC Boron-containing small molecules
Aug, 2026

(7 months from now)

US9572823

(Pediatric)

ANACOR PHARMS INC Boron-containing small molecules
Aug, 2026

(7 months from now)

US9549938

(Pediatric)

ANACOR PHARMS INC Boron-containing small molecules
Aug, 2026

(7 months from now)

US9549938 ANACOR PHARMS INC Boron-containing small molecules
Feb, 2026

(a month from now)

US7767657 ANACOR PHARMS INC Boron-containing small molecules
May, 2027

(1 year, 4 months from now)

US9572823 ANACOR PHARMS INC Boron-containing small molecules
Feb, 2026

(a month from now)

US9566289

(Pediatric)

ANACOR PHARMS INC Boron-containing small molecules
Aug, 2026

(7 months from now)

US7582621

(Pediatric)

ANACOR PHARMS INC Boron-containing small molecules
Nov, 2027

(1 year, 10 months from now)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Jul 07, 2019
Pediatric Exclusivity(PED) Jan 07, 2020

Drugs and Companies using TAVABOROLE ingredient

NCE-1 date: 07 January, 2019

Market Authorisation Date: 07 July, 2014

Dosage: SOLUTION

How can I launch a generic of KERYDIN before it's drug patent expiration?
More Information on Dosage

KERYDIN family patents

Family Patents

8. Luzu patent expiration

Treatment: Treatment of fungal infections

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents protects the active chemical substance. Only drug patent owner can launch products that use this active substance.
US9012484 BAUSCH Crystal and pharmaceutical preparation containing the same crystal
Sep, 2033

(7 years from now)

US5900488 BAUSCH Method for treating mycosis using imidazolylacetonitrile derivatives
Jan, 2020

(5 years ago)

US9453006 BAUSCH Crystalline form having specific crystal habit and pharmaceutical composition containing this crystalline form as active ingredient
Sep, 2033

(7 years from now)

US9199977 BAUSCH Crystal having crystal habits and pharmaceutical composition obtained by processing the crystal
Sep, 2033

(7 years from now)

These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US8980931 BAUSCH Method of evaluating pharmaceutical preparation containing luliconazole and index substance
Apr, 2034

(8 years from now)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Nov 14, 2018
New Patient Population(NPP) Feb 20, 2021

Drugs and Companies using LULICONAZOLE ingredient

NCE-1 date: 14 November, 2017

Market Authorisation Date: 14 November, 2013

Dosage: CREAM

More Information on Dosage

LUZU family patents

Family Patents

9. Mycamine patent expiration

Treatment: Treatment of esophageal candidiasis and prophylaxis of candida infections in hsct patients; Treatment of patients with candidemia, acute disseminated candidiasis, candida peritonitis and abscesses

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US6265536 ASTELLAS Cyclic hexapeptides having antibiotic activity
Sep, 2015

(10 years ago)

US6107458 ASTELLAS Cyclic hexapeptides having antibiotic activity
Mar, 2019

(6 years ago)

US6774104

(Pediatric)

ASTELLAS Stabilized pharmaceutical composition in lyophilized form
Jul, 2021

(4 years ago)

US6774104 ASTELLAS Stabilized pharmaceutical composition in lyophilized form
Jan, 2021

(5 years ago)




Drug Exclusivity Drug Exclusivity Expiration
New Indication(I-821) Dec 20, 2022
Pediatric Exclusivity(PED) Jun 20, 2023

Drugs and Companies using MICAFUNGIN SODIUM ingredient

Market Authorisation Date: 16 March, 2005

Dosage: INJECTABLE

How can I launch a generic of MYCAMINE before it's drug patent expiration?
More Information on Dosage

MYCAMINE family patents

Family Patents

10. Noxafil patent expiration

Treatment: Prophylaxis of invasive aspergillus and candida infections and treatment of oropharyngeal candidiasis

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US5661151 SCHERING Tetrahydrofuran antifungals
Jul, 2019

(6 years ago)

US8263600 SCHERING Antifungal composition with enhanced bioavailability
Apr, 2022

(3 years ago)

US5703079 SCHERING Tetrahydrofuran antifungals
Aug, 2014

(11 years ago)

US6958337 SCHERING Crystalline antifungal polymorph
Oct, 2018

(7 years ago)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Sep 15, 2011
New Patient Population(NPP) May 31, 2024
New Indication(I-881) Jun 17, 2024
Orphan Drug Exclusivity(ODE-355) Jun 17, 2028

Drugs and Companies using POSACONAZOLE ingredient

NCE-1 date: 15 September, 2010

Market Authorisation Date: 15 September, 2006

Dosage: SUSPENSION

How can I launch a generic of NOXAFIL before it's drug patent expiration?
More Information on Dosage

NOXAFIL family patents

Family Patents

11. Noxafil patent expiration

Treatment: Prophylaxis of invasive aspergillus and candida infections in adults and pediatric patients 2 years of age and older who are severely immunocompromised; Prophylaxis of invasive aspergillus and candida...

NOXAFIL's oppositions filed in EPO
Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents protects the active chemical substance. Only drug patent owner can launch products that use this active substance.
US5661151 MERCK SHARP DOHME Tetrahydrofuran antifungals
Jul, 2019

(6 years ago)

US5703079 MERCK SHARP DOHME Tetrahydrofuran antifungals
Aug, 2014

(11 years ago)

These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US9358297 MERCK SHARP DOHME Posaconazole intravenous solution formulations stabilized by substituted β-cyclodextrin
Jun, 2031

(5 years from now)

US9023790 MERCK SHARP DOHME Posaconazole intravenous solution formulations stabilized by substituted β-cyclodextrin
Jul, 2031

(5 years from now)

US9750822 MERCK SHARP DOHME Sulfoalkyl ether cyclodextrin compositions
Mar, 2029

(3 years from now)

US9493582 MERCK SHARP DOHME Alkylated cyclodextrin compositions and processes for preparing and using the same
Feb, 2033

(7 years from now)

US10117951 MERCK SHARP DOHME Sulfoalkyl ether cyclodextrin compositions
Mar, 2029

(3 years from now)

US8410077 MERCK SHARP DOHME Sulfoalkyl ether cyclodextrin compositions
Mar, 2029

(3 years from now)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Sep 15, 2011
New Patient Population(NPP) May 31, 2024
New Indication(I-881) Jun 17, 2024
Orphan Drug Exclusivity(ODE-355) Jun 17, 2028

Drugs and Companies using POSACONAZOLE ingredient

Market Authorisation Date: 13 March, 2014

Dosage: SOLUTION; TABLET, DELAYED RELEASE

How can I launch a generic of NOXAFIL before it's drug patent expiration?
More Information on Dosage

NOXAFIL family patents

Family Patents

12. Rezzayo patent expiration

Treatment: Treatment of candidemia and invasive candidiasis with rezafungin by intravenous administration

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents protects the active chemical substance. Only drug patent owner can launch products that use this active substance.
US10702573 MUNDIPHARMA Dosing regimens for echinocandin class compounds
Mar, 2033

(7 years from now)

US9526835 MUNDIPHARMA Dosing regimens for echinocandin class compounds
Mar, 2033

(7 years from now)

US8722619 MUNDIPHARMA Antifungal agents and uses thereof
Mar, 2032

(6 years from now)

US11197909 MUNDIPHARMA Compositions and methods for the treatment of fungal infections
Jul, 2038

(12 years from now)

US11654196 MUNDIPHARMA Dosing regimens for echinocandin class compounds
Mar, 2032

(6 years from now)

US11819533 MUNDIPHARMA Compositions and methods for the treatment of fungal infections
Jul, 2038

(12 years from now)

These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US11712459 MUNDIPHARMA Dosing regimens for treatment of fungal infections
Mar, 2037

(11 years from now)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Mar 22, 2028
Orphan Drug Exclusivity(ODE-426) Mar 22, 2030
Generating Antibiotic Incentives Now(GAIN) Mar 22, 2033

Drugs and Companies using REZAFUNGIN ACETATE ingredient

NCE-1 date: 22 March, 2032

Market Authorisation Date: 22 March, 2023

Dosage: POWDER

More Information on Dosage

REZZAYO family patents

Family Patents

13. Vfend patent expiration

Treatment: Treatment of fungal infections

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US5567817 PF PRISM CV Triazole antifungal agents
May, 2016

(9 years ago)

US6632803 PF PRISM CV Pharmaceutical formulations containing voriconazole
Jun, 2018

(7 years ago)




Drug Exclusivity Drug Exclusivity Expiration
New Patient Population(NPP) Jan 29, 2022

Drugs and Companies using VORICONAZOLE ingredient

Market Authorisation Date: 24 May, 2002

Dosage: TABLET; POWDER; FOR SUSPENSION

How can I launch a generic of VFEND before it's drug patent expiration?
More Information on Dosage

VFEND family patents

Family Patents

14. Vivjoa patent expiration

Treatment: Vivjoa is indicated to reduce the incidence of recurrent vulvovaginal candidiasis (rvvc) in females with a history of rvvc who are not of reproductive potential

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents protects the active chemical substance. Only drug patent owner can launch products that use this active substance.
US8236962 MYCOVIA PHARMS Metalloenzyme inhibitor compounds
Apr, 2031

(5 years from now)

US9840492 MYCOVIA PHARMS Antifungal compounds and processes for making
Mar, 2036

(10 years from now)

US10414751 MYCOVIA PHARMS Antifungal compounds and processes for making
Mar, 2036

(10 years from now)

These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US11247981 MYCOVIA PHARMS Metalloenzyme inhibitor compounds
May, 2033

(7 years from now)

US8754227 MYCOVIA PHARMS Metalloenzyme inhibitor compounds
Apr, 2031

(5 years from now)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Apr 26, 2027
Generating Antibiotic Incentives Now(GAIN) Apr 26, 2032

Drugs and Companies using OTESECONAZOLE ingredient

NCE-1 date: 27 April, 2031

Market Authorisation Date: 26 April, 2022

Dosage: CAPSULE

More Information on Dosage

VIVJOA family patents

Family Patents