Posaconazole Patent Expiration

Posaconazole is used for preventing and treating fungal infections in severely immunocompromised patients aged 2 years and older. It was first introduced by Schering Corp in its drug Noxafil on Sep 15, 2006. Another drug containing Posaconazole is Noxafil Powdermix Kit. 23 different companies have introduced drugs containing Posaconazole.


Posaconazole Patents

Given below is the list of patents protecting Posaconazole, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Noxafil US9493582 Alkylated cyclodextrin compositions and processes for preparing and using the same Feb 27, 2033 Merck Sharp Dohme
Noxafil US9023790 Posaconazole intravenous solution formulations stabilized by substituted β-cyclodextrin Jul 04, 2031 Merck Sharp Dohme
Noxafil US9358297 Posaconazole intravenous solution formulations stabilized by substituted β-cyclodextrin Jun 24, 2031 Merck Sharp Dohme
Noxafil US10117951 Sulfoalkyl ether cyclodextrin compositions Mar 13, 2029 Merck Sharp Dohme
Noxafil US8410077 Sulfoalkyl ether cyclodextrin compositions Mar 13, 2029 Merck Sharp Dohme
Noxafil US9750822 Sulfoalkyl ether cyclodextrin compositions Mar 13, 2029 Merck Sharp Dohme
Noxafil US8263600 Antifungal composition with enhanced bioavailability Apr 01, 2022

(Expired)

Schering
Noxafil US5661151 Tetrahydrofuran antifungals Jul 19, 2019

(Expired)

Schering
Noxafil US5661151 Tetrahydrofuran antifungals Jul 19, 2019

(Expired)

Merck Sharp Dohme
Noxafil US6958337 Crystalline antifungal polymorph Oct 05, 2018

(Expired)

Schering
Noxafil US5703079 Tetrahydrofuran antifungals Aug 26, 2014

(Expired)

Schering
Noxafil US5703079 Tetrahydrofuran antifungals Aug 26, 2014

(Expired)

Merck Sharp Dohme



Posaconazole's Family Patents

Family Patents

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Posaconazole Generic API Manufacturers

Several generic applications have been filed for Posaconazole. The first generic version for Posaconazole was by Sinotherapeutics Inc and was approved on Aug 21, 2019. And the latest generic version is by Qilu Pharmaceutical Hainan Co Ltd and was approved on Apr 23, 2025.

Given below is the list of companies who have filed for Posaconazole generic, along with the locations of their manufacturing plants worldwide.