Desmoid Tumors With Progressive Disease Therapeutics

1. Ogsiveo patent expiration

Treatment: Treatment of adult patients with progressing desmoid tumors

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents protects the active chemical substance. Only drug patent owner can launch products that use this active substance.
US10941118 SPRINGWORKS Solid state forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide and uses thereof
Aug, 2039

(13 years from now)

US10710966 SPRINGWORKS Solid state forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide and uses thereof
Aug, 2039

(13 years from now)

US11845732 SPRINGWORKS Solid state forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide and uses thereof
Aug, 2039

(13 years from now)

US7795447 SPRINGWORKS Imidazole compounds for the treatment of neurodegenerative disorders
Aug, 2030

(4 years from now)

US7951958 SPRINGWORKS Imidazole compounds for the treatment of neurodegenerative disorders
Mar, 2025

(9 months ago)

US7342118 SPRINGWORKS Imidazole compounds for the treatment of neurodegenerative disorders
Aug, 2025

(4 months ago)

US10590087 SPRINGWORKS Solid state forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide and uses thereof
Aug, 2039

(13 years from now)

These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US11612588 SPRINGWORKS Chlorinated tetralin compounds and pharmaceutical compositions
Jul, 2042

(16 years from now)

US11844780 SPRINGWORKS Chlorinated tetralin compounds and pharmaceutical compositions
Sep, 2042

(16 years from now)

US12011434 SPRINGWORKS Treatments with nirogacestat
May, 2043

(17 years from now)

US12138246 SPRINGWORKS Treatments with nirogacestat
May, 2043

(17 years from now)

US11957662 SPRINGWORKS Treatments with nirogacestat
May, 2043

(17 years from now)

US11951096 SPRINGWORKS Treatments with nirogacestat
May, 2043

(17 years from now)

US11925620 SPRINGWORKS Treatments with nirogacestat
May, 2043

(17 years from now)

US11925619 SPRINGWORKS Treatments with nirogacestat
May, 2043

(17 years from now)

US11938116 SPRINGWORKS Treatments with nirogacestat
May, 2043

(17 years from now)

US11807611 SPRINGWORKS Chlorinated tetralin compounds and pharmaceutical compositions
Sep, 2042

(16 years from now)

US12011435 SPRINGWORKS Treatments with nirogacestat
May, 2043

(17 years from now)

US12036207 SPRINGWORKS Treatments with nirogacestat
May, 2043

(17 years from now)

US11872211 SPRINGWORKS Treatments with nirogacestat
May, 2043

(17 years from now)

US12247012 SPRINGWORKS Synthesis of nirogacestat
Jul, 2042

(16 years from now)

US11884635 SPRINGWORKS Solid state forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide and uses thereof
Aug, 2039

(13 years from now)

US11820748 SPRINGWORKS Solid state forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide and uses thereof
Aug, 2039

(13 years from now)

US12110277 SPRINGWORKS Synthesis of nirogacestat
Jul, 2042

(16 years from now)

US11504354 SPRINGWORKS Chlorinated tetralin compounds and pharmaceutical compositions
Jul, 2042

(16 years from now)

US11905255 SPRINGWORKS Solid state forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide and uses thereof
Aug, 2039

(13 years from now)

US12116347 SPRINGWORKS Solid state forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide and uses thereof
Aug, 2039

(13 years from now)

US12234210 SPRINGWORKS Synthesis of nirogacestat
Jul, 2042

(16 years from now)

US11884634 SPRINGWORKS Compositions of solid forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4- tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide
Aug, 2039

(13 years from now)

US12297177 SPRINGWORKS Solid state forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide and uses thereof
Aug, 2039

(13 years from now)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Nov 27, 2028
ODE*(ODE*) Nov 27, 2030
Orphan Drug Exclusivity(ODE-452) Nov 27, 2030

Drugs and Companies using NIROGACESTAT HYDROBROMIDE ingredient

NCE-1 date: 28 November, 2027

Market Authorisation Date: 27 November, 2023

Dosage: TABLET

More Information on Dosage

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