Metformin Hydrochloride; Sitagliptin Phosphate Patent Expiration
Metformin Hydrochloride; Sitagliptin Phosphate is used for managing type 2 diabetes mellitus with the combination of sitagliptin and metformin HCl extended release, either alone or with insulin. It was first introduced by Merck Sharp And Dohme Llc A Sub Of Merck And Co Inc
Metformin Hydrochloride; Sitagliptin Phosphate Patents
Given below is the list of patents protecting Metformin Hydrochloride; Sitagliptin Phosphate, along with the drug name that holds that patent and the company name owning that drug.
Drug Used in | Drug Patent Number | Drug Patent Title | Drug Patent Expiry | Drug Owner |
---|---|---|---|---|
Janumet |
US8414921 (Pediatric) | Pharmaceutical compositions of combinations of dipeptidyl peptidase-4 inhibitors with metformin | Jan 21, 2029 | Msd Sub Merck |
Janumet | US8414921 | Pharmaceutical compositions of combinations of dipeptidyl peptidase-4 inhibitors with metformin | Jul 21, 2028 | Msd Sub Merck |
Janumet |
US7326708 (Pediatric) | Phosphoric acid salt of a dipeptidyl peptidase-IV inhibitor | May 24, 2027 | Msd Sub Merck |
Janumet Xr |
US7326708 (Pediatric) | Phosphoric acid salt of a dipeptidyl peptidase-IV inhibitor | May 24, 2027 | Msd Sub Merck |
Janumet | US7326708 | Phosphoric acid salt of a dipeptidyl peptidase-IV inhibitor | Nov 24, 2026 | Msd Sub Merck |
Janumet Xr | US7326708 | Phosphoric acid salt of a dipeptidyl peptidase-IV inhibitor | Nov 24, 2026 | Msd Sub Merck |
Janumet |
US6699871 (Pediatric) | Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
Jan 26, 2023
(Expired) | Msd Sub Merck |
Janumet |
US7125873 (Pediatric) | Beta-amino tetrahydroimidazo (1, 2-a) pyrazines and tetrahydrotrioazolo (4, 3-a) pyrazines as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
Jan 26, 2023
(Expired) | Msd Sub Merck |
Janumet Xr |
US6699871 (Pediatric) | Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
Jan 26, 2023
(Expired) | Msd Sub Merck |
Janumet Xr |
US7125873 (Pediatric) | Beta-amino tetrahydroimidazo (1, 2-a) pyrazines and tetrahydrotrioazolo (4, 3-a) pyrazines as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
Jan 26, 2023
(Expired) | Msd Sub Merck |
Janumet | US6699871 | Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
Jul 26, 2022
(Expired) | Msd Sub Merck |
Janumet | US7125873 | Beta-amino tetrahydroimidazo (1, 2-a) pyrazines and tetrahydrotrioazolo (4, 3-a) pyrazines as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
Jul 26, 2022
(Expired) | Msd Sub Merck |
Janumet Xr | US6699871 | Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
Jul 26, 2022
(Expired) | Msd Sub Merck |
Janumet Xr | US7125873 | Beta-amino tetrahydroimidazo (1, 2-a) pyrazines and tetrahydrotrioazolo (4, 3-a) pyrazines as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
Jul 26, 2022
(Expired) | Msd Sub Merck |
Janumet | US6890898 | Method of regulating glucose metabolism, and reagents related thereto |
Feb 02, 2019
(Expired) | Msd Sub Merck |
Janumet | US7078381 | Method of regulating glucose metabolism, and reagents related thereto |
Feb 02, 2019
(Expired) | Msd Sub Merck |
Janumet | US7459428 | Method of regulating glucose metabolism, and reagents related thereto |
Feb 02, 2019
(Expired) | Msd Sub Merck |
Janumet Xr | US6890898 | Method of regulating glucose metabolism, and reagents related thereto |
Feb 02, 2019
(Expired) | Msd Sub Merck |
Janumet Xr | US7078381 | Method of regulating glucose metabolism, and reagents related thereto |
Feb 02, 2019
(Expired) | Msd Sub Merck |
Janumet Xr | US7459428 | Method of regulating glucose metabolism, and reagents related thereto |
Feb 02, 2019
(Expired) | Msd Sub Merck |
Janumet | US6303661 | Use of dipeptidyl peptidase IV effectors for lowering the blood glucose level in mammals |
Apr 24, 2017
(Expired) | Msd Sub Merck |
Janumet Xr | US6303661 | Use of dipeptidyl peptidase IV effectors for lowering the blood glucose level in mammals |
Apr 24, 2017
(Expired) | Msd Sub Merck |
Janumet Xr | US6340475 | Extending the duration of drug release within the stomach during the fed mode |
Sep 19, 2016
(Expired) | Msd Sub Merck |
Janumet Xr | US6635280 | Extending the duration of drug release within the stomach during the fed mode |
Sep 19, 2016
(Expired) | Msd Sub Merck |
Metformin Hydrochloride; Sitagliptin Phosphate's Family Patents

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Metformin Hydrochloride; Sitagliptin Phosphate Generic API Manufacturers
Several generic applications have been filed for Metformin Hydrochloride; Sitagliptin Phosphate.
Given below is the list of companies who have filed for Metformin Hydrochloride; Sitagliptin Phosphate generic, along with the locations of their manufacturing plants worldwide.
1. ENDO OPERATIONS
Endo Operations Ltd has filed for 3 different strengths of generic version for Metformin Hydrochloride; Sitagliptin Phosphate. All of these versions come by the name SITAGLIPTIN AND METFORMIN HYDROCHLORIDE. Given below are the details of the strengths of this generic introduced by Endo Operations.
Strength | Dosage Form | Availability | Application Pathway | TE code | Launch Date |
---|---|---|---|---|---|
500MG; EQ 50MG BASE | tablet, extended release | Prescription | ORAL | AB | Jun 4, 2025 |
1GM; EQ 50MG BASE | tablet, extended release | Prescription | ORAL | AB | Jun 4, 2025 |
1GM; EQ 100MG BASE | tablet, extended release | Prescription | ORAL | AB | Jun 4, 2025 |