Diltiazem Hydrochloride was first introduced by Bausch Health Us Llc in its drug Cardizem on Nov 5, 1982. Other drugs containing Diltiazem Hydrochloride are Cardizem La, Diltiazem Hydrochloride, Tiazac, Dilacor Xr, Diltiazem Hydrochloride In Dextrose 5%, Diltiazem Hydrochloride In 0.72% Sodium Chloride, Cardizem Sr, Cardizem Cd. 43 different companies have introduced drugs containing Diltiazem Hydrochloride.

Diltiazem Hydrochloride Patents

Given below is the list of patents protecting Diltiazem Hydrochloride, along with the drug name that holds that patent and the company name owning that drug.

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Drug Used in	Drug Patent Number	Drug Patent Title	Drug Patent Expiry	Drug Owner
Cardizem La	US6923984	Cushioning wax beads for making solid shaped articles	Feb 25, 2021 (Expired)	Bausch
Cardizem La	US7108866	Chronotherapeutic diltiazem formulations and the administration thereof	Dec 17, 2019 (Expired)	Bausch
Cardizem La	US5529791	Extended release form of diltiazem	Jun 25, 2013 (Expired)	Bausch
Diltiazem Hydrochloride	US5529791	Extended release form of diltiazem	Jun 25, 2013 (Expired)	Biovail
Tiazac	US5529791	Extended release form of diltiazem	Jun 25, 2013 (Expired)	Bausch
Cardizem Cd	US5439689	Diltiazem formulation	Aug 08, 2012 (Expired)	Bausch

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Diltiazem Hydrochloride Generic API Manufacturers

Several generic applications have been filed for Diltiazem Hydrochloride. The first generic version for Diltiazem Hydrochloride was by Rising Pharma Holding Inc and was approved on Nov 5, 1992. And the latest generic version is by Zydus Lifesciences Global Fze and was approved on Aug 8, 2025.

Given below is the list of companies who have filed for Diltiazem Hydrochloride generic, along with the locations of their manufacturing plants worldwide.