Colchicine is Used for treating and reducing the risk of cardiovascular events, acute myocardial infarction, atherosclerotic vascular disease, and inflammation. It was first introduced by Takeda Pharmaceuticals Usa Inc in its drug Colcrys on Jul 29, 2009. Other drugs containing Colchicine are Gloperba, Mitigare, Lodoco. 16 different companies have introduced drugs containing Colchicine.

Colchicine Patents

Given below is the list of patents protecting Colchicine, along with the drug name that holds that patent and the company name owning that drug.

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Drug Used in	Drug Patent Number	Drug Patent Title	Drug Patent Expiry	Drug Owner
Gloperba	US10226423	Colchicine drug-to-drug interactions	Dec 20, 2037	Scilex Pharms
Gloperba	US10383820	Colchicine drug-to-drug interactions	Nov 22, 2036	Scilex Pharms
Gloperba	US10383821	Colchicine drug-to-drug interactions	Nov 22, 2036	Scilex Pharms
Gloperba	US12274751	Composition and method of the use of colchicine oral liquid	Nov 22, 2036	Scilex Pharms
Gloperba	US9907751	Composition and method of use of colchicine oral liquid	Nov 22, 2036	Scilex Pharms
Lodoco	US10130585	Methods of treating and/or preventing cardiovascular disease	May 09, 2034	Agepha Pharma Fz
Lodoco	US10206891	Method of treating cardiovascular events using colchicine concurrently with an antiplatelet agent	Nov 01, 2033	Agepha Pharma Fz
Lodoco	US10265281	Treatment or prevention of cardiovascular events via the administration of a colchicine derivative	Nov 01, 2033	Agepha Pharma Fz
Lodoco	US10842762	Method of treating cardiovascular events using colchicine concurrently with an antiplatelet agent	Nov 01, 2033	Agepha Pharma Fz
Lodoco	US11026899	Treatment or prevention of cardiovascular events via the administration of a colchicine derivative	Nov 01, 2033	Agepha Pharma Fz
Lodoco	US11026900	Treatment or prevention of cardiovascular events via the administration of a colchicine derivative	Nov 01, 2033	Agepha Pharma Fz
Lodoco	US11026901	Treatment or prevention of cardiovascular events via the administration of a colchicine derivative	Nov 01, 2033	Agepha Pharma Fz
Lodoco	US11944594	Treatment or prevention of cardiovascular events via the administration of a colchicine derivative	Nov 01, 2033	Agepha Pharma Fz
Lodoco	US11944595	Treatment or prevention of cardiovascular events via the administration of a colchicine derivative	Nov 01, 2033	Agepha Pharma Fz
Lodoco	US12233035	Method of treating cardiovascular events using colchicine concurrently with an antiplatelet agent and statin	Nov 01, 2033	Agepha Pharma Fz
Lodoco	US12280025	Treatment or prevention of cardiovascular events via the administration of a colchicine derivative	Nov 01, 2033	Agepha Pharma Fz
Lodoco	US9744144	Method of treating cardiovascular events using colchicine concurrently with an antiplatelet agent	Nov 01, 2033	Agepha Pharma Fz
Mitigare	US8927607	Methods of colchicine administration	Aug 22, 2033	Hikma Intl Pharms
Mitigare	US9399036	Methods of colchicine administration	Aug 22, 2033	Hikma Intl Pharms
Mitigare	US9555029	Methods of colchicine administration	Aug 22, 2033	Hikma Intl Pharms
Mitigare	US9675613	Methods of colchicine administration	Aug 22, 2033	Hikma Intl Pharms
Mitigare	US9789108	Methods of colchicine administration	Aug 22, 2033	Hikma Intl Pharms
Colcrys	US7820681	Methods for concomitant administration of colchicine and a second active agent	Feb 17, 2029	Takeda Pharms Usa
Colcrys	US7906519	Methods for concomitant administration of colchicine and a second active agent	Feb 17, 2029	Takeda Pharms Usa
Colcrys	US7915269	Methods for concomitant administration of colchicine and a second active agent	Feb 17, 2029	Takeda Pharms Usa
Colcrys	US8440721	Methods for concomitant administration of colchicine and a second active agent	Feb 17, 2029	Takeda Pharms Usa
Colcrys	US8440722	Methods for concomitant administration of colchicine and a second active agent	Feb 17, 2029	Takeda Pharms Usa
Colcrys	US7601758	Methods for concomitant administration of colchicine and macrolide antibiotics in the treatment of gout flares	Feb 10, 2029	Takeda Pharms Usa
Colcrys	US7619004	Methods for concomitant administration of colchicine and macrolide antibiotics	Dec 03, 2028	Takeda Pharms Usa
Colcrys	US7935731	Methods for concomitant administration of colchicine and macrolide antibiotics	Dec 03, 2028	Takeda Pharms Usa
Colcrys	US7964647	Colchicine compositions and methods	Oct 06, 2028	Takeda Pharms Usa
Colcrys	US7964648	Methods for concomitant administration of colchicine and a second active agent	Oct 06, 2028	Takeda Pharms Usa
Colcrys	US7981938	Colchicine compositions and methods	Oct 06, 2028	Takeda Pharms Usa
Colcrys	US8093296	Methods for concomitant administration of colchicine and macrolide antibiotics	Oct 06, 2028	Takeda Pharms Usa
Colcrys	US8093297	Methods for concomitant administration of colchicine and a second active agent	Oct 06, 2028	Takeda Pharms Usa
Colcrys	US8093298	Methods for concomitant administration of colchicine and macrolide antibiotics	Oct 06, 2028	Takeda Pharms Usa
Colcrys	US8097655	Methods for concomitant administration of colchicine and macrolide antibiotics	Oct 06, 2028	Takeda Pharms Usa
Colcrys	US8415395	Colchicine compositions and methods	Oct 06, 2028	Takeda Pharms Usa
Colcrys	US8415396	Colchine compositions and methods	Oct 06, 2028	Takeda Pharms Usa

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Colchicine's Family Patents

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Colchicine Generic API Manufacturers

Several generic applications have been filed for Colchicine. The first generic version for Colchicine was by Amneal Pharmaceuticals and was approved on Sep 28, 2016. And the latest generic version is by Granules Pharmaceuticals Inc and was approved on Apr 29, 2024.

Given below is the list of companies who have filed for Colchicine generic, along with the locations of their manufacturing plants worldwide.