Cabazitaxel Patent Expiration

Cabazitaxel is used for treating metastatic castration-resistant prostate cancer after prior treatment with docetaxel by administering cabazitaxel in combination with prednisone or prednisolone. It was first introduced by Sanofi Aventis Us Inc in its drug Jevtana Kit on Jun 17, 2010. Another drug containing Cabazitaxel is Cabazitaxel. 8 different companies have introduced drugs containing Cabazitaxel.


Cabazitaxel Patents

Given below is the list of patents protecting Cabazitaxel, along with the drug name that holds that patent and the company name owning that drug.

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Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Jevtana Kit US10583110

(Pediatric)

Antitumoral Use Of Cabazitaxel Apr 27, 2031 Sanofi Aventis Us
Jevtana Kit US10716777

(Pediatric)

Antitumoral Use Of Cabazitaxel Apr 27, 2031 Sanofi Aventis Us
Jevtana Kit US12453712

(Pediatric)

Antitumoral Use Of Cabazitaxel Apr 27, 2031 Sanofi Aventis Us
Jevtana Kit US8927592

(Pediatric)

Antitumoral use of cabazitaxel Apr 27, 2031 Sanofi Aventis Us
Jevtana Kit US10583110 Antitumoral use of cabazitaxel Oct 27, 2030 Sanofi Aventis Us
Jevtana Kit US10716777 Antitumoral use of cabazitaxel Oct 27, 2030 Sanofi Aventis Us
Jevtana Kit US12453712 Antitumoral Use Of Cabazitaxel Oct 27, 2030 Sanofi Aventis Us
Jevtana Kit US8927592 Antitumoral use of cabazitaxel Oct 27, 2030 Sanofi Aventis Us
Jevtana Kit US7241907

(Pediatric)

Acetone solvate of dimethoxy docetaxel and its process of preparation Jun 10, 2026

(Expired)

Sanofi Aventis Us
Jevtana Kit US7241907 Acetone solvate of dimethoxy docetaxel and its process of preparation Dec 10, 2025

(Expired)

Sanofi Aventis Us
Jevtana Kit US5847170

(Pediatric)

Taxoids, their preparation and pharmaceutical compositions containing them Sep 26, 2021

(Expired)

Sanofi Aventis Us
Jevtana Kit US5847170 Taxoids, their preparation and pharmaceutical compositions containing them Mar 26, 2016

(Expired)

Sanofi Aventis Us
Jevtana Kit US6331635 Taxoids, their preparation and pharmaceutical compositions containing them Mar 26, 2016

(Expired)

Sanofi Aventis Us
Jevtana Kit US6372780 Methods of treating cell lines expressing multidrug resistance P-glycoprotein Mar 26, 2016

(Expired)

Sanofi Aventis Us
Jevtana Kit US6387946 Methods for treating pathological conditions of abnormal cell proliferation Mar 26, 2016

(Expired)

Sanofi Aventis Us
Jevtana Kit US5438072 Taxoid-based compositions Nov 22, 2013

(Expired)

Sanofi Aventis Us
Jevtana Kit US5698582 Compositions containing taxane derivatives Jul 03, 2012

(Expired)

Sanofi Aventis Us



Cabazitaxel's Family Patents

Family Patents

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Clinical Trials

Recent Clinical Trials on Cabazitaxel:

Sometimes companies keep conducting clinical trials even after the drug's approval to discover new formulations, methods of use, or new treatment indications, so they could file for additional patents or receive regulatory exclusivity extensions, such as pediatric exclusivity, potentially delaying generic competition. Based on these recent clinical trials, generic companies need to consider the potential for new intellectual property or regulatory hurdles. These strategic moves by the drug owner might delay generic substitution or lead to additional sales of the brand drug, even after patent expiry.

Title Lead Sponsor Collaborators Status Phases
Clinical Trials
Enzalutamide and Cabazitaxel in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer OHSU Knight Cancer Institute NA ACTIVE NOT RECRUITING
(Sep 1, 2026)
PHASE1, PHASE2
Docetaxel or Cabazitaxel With or Without Darolutamide in mCRPC Erasmus Medical Center NA RECRUITING
(Sep 1, 2026)
PHASE2
Phase I/II Study of PEGylated Arginine Deiminase (ADI-PEG20) With Carboplatin and Cabazitaxel in Men With Aggressive Variant Prostate Cancers (AVPC) M.D. Anderson Cancer Center NA RECRUITING
(Sep 1, 2026)
PHASE1, PHASE2
Substudy 01A: Safety and Efficacy of Opevesostat (MK-5684)-Based Treatment Combinations or Opevesostat Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-01A) Merck Sharp & Dohme LLC NA RECRUITING
(Sep 1, 2026)
PHASE1, PHASE2
Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC Novartis Pharmaceuticals NA RECRUITING
(Sep 1, 2026)
PHASE3
AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01) AstraZeneca NA RECRUITING
(Aug 1, 2026)
PHASE3
Study of Olaparib Maintenance Following Cabazitaxel-Carbo in Men With AVPC M.D. Anderson Cancer Center NA COMPLETED
(Jun 1, 2026)
PHASE2
Cabazitaxel, Carboplatin, and Cetrelimab Followed by Niraparib With or Without Cetrelimab for the Treatment of Aggressive Variant Metastatic Prostate Cancer M.D. Anderson Cancer Center NA ACTIVE NOT RECRUITING
(Jun 1, 2026)
PHASE2
Darolutamide in Metastatic Castration-Resistant Prostate Cancer (mCRPC) Swiss Cancer Institute NA RECRUITING
(Jun 1, 2026)
PHASE2
Telmisartan in Prostate Cancer Tyler J Curiel NA RECRUITING
(May 1, 2026)
PHASE1
Phase 3 Study of Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy in Participants With Progressive Metastatic Castration-Resistant Prostate Cancer (XALute) Amgen NA ACTIVE NOT RECRUITING
(May 1, 2026)
PHASE3
CASCARA: Castration Sensitive Carboplatin, Cabazitaxel and Abiraterone Masonic Cancer Center, University of Minnesota NA COMPLETED
(Apr 1, 2026)
PHASE2
A Study of Chemoimmunotherapy for the Treatment of Men With Neuroendocrine or Aggressive Variant Metastatic Prostate Cancer Andrew J. Armstrong, MD NA ACTIVE NOT RECRUITING
(Apr 1, 2026)
PHASE2
A Prospective Study of Cabazitaxel in Patients With Non Seminomatous Germ-cell Tumors Gustave Roussy, Cancer Campus, Grand Paris NA COMPLETED
(Mar 1, 2026)
PHASE2


Cabazitaxel Generic API Manufacturers

Several generic applications have been filed for Cabazitaxel. The first generic version for Cabazitaxel was by Breckenridge Pharmaceutical Inc and was approved on Jun 23, 2022. And the latest generic version is by Mylan Laboratories Ltd and was approved on Jul 5, 2023.

Given below is the list of companies who have filed for Cabazitaxel generic, along with the locations of their manufacturing plants worldwide.