Cubist Pharms Llc Drug Patent Portfolio

Cubist Pharms Llc owns 5 orange book drugs protected by 40 US patents with Cubicin Rf having the least patent protection, holding only 1 patent. And Zerbaxa with maximum patent protection, holding 14 patents. Given below is the list of Cubist Pharms Llc's drug patents along with their expiration dates.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US10125149 Synthesis of cephalosporin compounds 14 Aug, 2035
Active
US9808530 Composition of tiacumicin compounds 28 Nov, 2034
Active
US10376496 Treating infections with ceftolozane/tazobactam in subjects having impaired renal function 09 Sep, 2034
Active
US10933053 Treating infections with ceftolozane/tazobactam in subjects having impaired renal function 09 Sep, 2034
Active
US9808530 Composition of tiacumicin compounds 28 May, 2034
Active
US8906898 Solid forms of ceftolozane 28 May, 2034
Active
US10420841 Ceftolozane antibiotic compositions 14 Mar, 2034
Active
US11278622 Ceftolozane antibiotic compositions 14 Mar, 2034
Active
US8968753 Ceftolozane-tazobactam pharmaceutical compositions 14 Mar, 2034
Active
US9320740 Ceftolozane-tazobactam pharmaceutical compositions 14 Mar, 2034
Active
US9872906 Ceftolozane antibiotic compositions 14 Mar, 2034
Active
US8476425 Tazobactam arginine compositions 27 Sep, 2032
Active
US8685957 Tazobactam arginine compositions 27 Sep, 2032
Active
US10028963 Methods for treating intrapulmonary infections 07 Sep, 2032
Active
US9724353 Methods for treating intrapulmonary infections 07 Sep, 2032
Active
US8426389 Crystalline form of R)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate 31 Dec, 2030
Active
US9138456 Lipopeptide compositions and related methods 23 Nov, 2030
Active
US10065947 Forms of R)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate 03 Feb, 2030
Active
US10442829 Forms of R)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate 03 Feb, 2030
Active
US9624250 Forms of R)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate 03 Feb, 2030
Active
US9988406 Forms of R)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate 03 Feb, 2030
Active
US8003673 Daptomycin for the treatment of biofilm and catheter salvage 04 Sep, 2028
Active
US7816379 Oxazolidinone derivatives 20 Jun, 2028
Active
US7129232 Cephem compounds 15 May, 2028
Active
US8420676 Oxazolidinone derivatives 23 Feb, 2028
Active
US7378508 Polymorphic crystalline forms of tiacumicin B 31 Jan, 2028
Active
US7863249 Macrolide polymorphs, compositions comprising such polymorphs, and methods of use and manufacture thereof 31 Jan, 2028
Active
US8859510 Macrocyclic polymorphs, compositions comprising such polymorphs, and methods of use and manufacture thereof 31 Jan, 2028
Active
US7906489 18-membered macrocycles and analogs thereof 04 Sep, 2027
Active
US7378508 Polymorphic crystalline forms of tiacumicin B 31 Jul, 2027
Active
US7863249 Macrolide polymorphs, compositions comprising such polymorphs, and methods of use and manufacture thereof 31 Jul, 2027
Active
US8859510 Macrocyclic polymorphs, compositions comprising such polymorphs, and methods of use and manufacture thereof 31 Jul, 2027
Active
US7906489 18-membered macrocycles and analogs thereof 04 Mar, 2027
Active
US8586551 18-membered macrocycles and analogs thereof 15 Jan, 2024 Expired
US8586551 18-membered macrocycles and analogs thereof 23 Jul, 2023 Expired
US8058238 High purity lipopeptides 28 Nov, 2020 Expired
US8129342 High purity lipopeptides 28 Nov, 2020 Expired
US6468967 Methods for administration of antibiotics 24 Sep, 2019 Expired
US6852689 Methods for administration of antibiotics 24 Sep, 2019 Expired
USRE39071 Anhydro-and isomer-a-21978c cyclic peptides 15 Jun, 2016 Expired


Given below is the list of recent legal activities going on the following drug patents of Cubist Pharms Llc.

Activity Date Patent Number
Patent litigations
Expire Patent 08 Apr, 2024 US8129342 (Litigated)
Expire Patent 18 Dec, 2023 US8058238 (Litigated)
Maintenance Fee Reminder Mailed 23 Oct, 2023 US8129342 (Litigated)
Maintenance Fee Reminder Mailed 03 Jul, 2023 US8058238 (Litigated)
Payment of Maintenance Fee, 4th Year, Large Entity 09 Mar, 2023 US10442829
Payment of Maintenance Fee, 8th Year, Large Entity 08 Feb, 2023 US9138456
Payment of Maintenance Fee, 4th Year, Large Entity 08 Feb, 2023 US10420841
Payment of Maintenance Fee, 8th Year, Large Entity 08 Feb, 2023 US9138456
Payment of Maintenance Fee, 4th Year, Large Entity 11 Jan, 2023 US10376496
Payment of Maintenance Fee, 12th Year, Large Entity 11 Jan, 2023 US8003673
Payment of Maintenance Fee, 12th Year, Large Entity 10 Aug, 2022 US7906489 (Litigated)
Payment of Maintenance Fee, 12th Year, Large Entity 08 Jun, 2022 US7863249 (Litigated)
Payment of Maintenance Fee, 8th Year, Large Entity 11 May, 2022 US8906898
Payment of Maintenance Fee, 4th Year, Large Entity 12 Apr, 2022 US10125149
Patent Issue Date Used in PTA Calculation 22 Mar, 2022 US11278622


Cubist Pharms Llc's Drug Patent Litigations

Cubist Pharms Llc's drugs have been subject to various legal proceedings, including patent litigations. The earliest legal proceeding was initiated on Oct 23, 2014, against patent number US8129342. The petitioner Agila Specialities Inc., challenged the validity of this patent, with Cubist Pharmaceuticals, Inc. as the respondent. Click below to track the latest information on how companies are challenging Cubist Pharms Llc's patents.

Patent Proceeding Filing Date Status Respondent Petitioner
Patent litigations
US9138456 November, 2019 Terminated-Denied
(29 May, 2020)
Cubist Pharmaceuticals LLC Amneal Pharmaceuticals LLC
US8058238 July, 2015 Terminated-Settled
(14 Jun, 2016)
Cubist Pharmaceuticals LLC Fresenius Kabi USA LLC
US8129342 July, 2015 Terminated-Settled
(14 Jun, 2016)
Cubist Pharmaceuticals LLC Fresenius Kabi USA LLC
US6468967 November, 2014 FWD Entered
(12 May, 2016)
Cubist Pharmaceuticals LLC Fresenius-Kabi USA LLC
US6852689 November, 2014 FWD Entered
(12 May, 2016)
Cubist Pharmaceuticals LLC Fresenius-Kabi USA LLC
US8058238 July, 2015 Terminated-Denied
(28 Jan, 2016)
Cubist Pharmaceuticals LLC Fresenius Kabi USA LLC
US6468967 October, 2014 Terminated-Denied
(28 Apr, 2015)
Cubist Pharmaceuticals, Inc. Agila Specialties Inc.
US6852689 October, 2014 Terminated-Denied
(28 Apr, 2015)
Cubist Pharmaceuticals Incorporated Agila Specialties Inc.
US8058238 October, 2014 Terminated-Denied
(28 Apr, 2015)
Cubist Pharmaceuticals, Inc. Agila Specialities Inc.
US8058238 October, 2014 Terminated-Denied
(28 Apr, 2015)
Cubist Pharmaceuticals, Inc. Agila Specialties Inc.
US8129342 October, 2014 Terminated-Denied
(28 Apr, 2015)
Cubist Pharmaceuticals, Inc. Agila Specialities Inc.


Cubist Pharms Llc Drug Patents' Oppositions Filed in EPO

Cubist Pharms Llc drug patents have faced multiple oppositions in the European Patent Office. The earliest opposition was filed on Apr 10, 2019, by Hgf Limited. This opposition was filed on patent number EP10832379A. Click below to reveal the latest opposition data.


Application Filing Date Opposition Party Legal Status
Patent litigations
EP14842042A Dec, 2020 Lederer & Keller Patentanwälte Partnerschaft mbB Opposition rejected
EP10832379A Apr, 2019 Pajaro Limited Granted and Under Opposition
EP10832379A Apr, 2019 HGF Limited Granted and Under Opposition


Cubist Pharms Llc's Family Patents

Cubist Pharms Llc drugs have patent protection in a total of 50 countries. It's US patent count contributes only to 28.2% of its total global patent coverage. 3 countries have all of their patents expired or invalidated which has opened up potential generic launch opportunities in these countries. Click below to unlock the full patent family tree.

Family Patents



Cubist Pharms Llc Drug List

Given below is the complete list of Cubist Pharms Llc's drugs and the patents protecting them.


1. Cubicin

Cubicin is protected by 7 patents, out of which 5 have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US9138456 Lipopeptide compositions and related methods 23 Nov, 2030
(6 years from now)
Active
US8003673 Daptomycin for the treatment of biofilm and catheter salvage 04 Sep, 2028
(3 years from now)
Active
US8058238 High purity lipopeptides 28 Nov, 2020
(3 years ago)
Expired
US8129342 High purity lipopeptides 28 Nov, 2020
(3 years ago)
Expired
US6468967 Methods for administration of antibiotics 24 Sep, 2019
(5 years ago)
Expired
US6852689 Methods for administration of antibiotics 24 Sep, 2019
(5 years ago)
Expired
USRE39071 Anhydro-and isomer-a-21978c cyclic peptides 15 Jun, 2016
(8 years ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Cubicin's drug page


2. Cubicin Rf

Cubicin Rf is protected by 1 patent, which is still active. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US9138456 Lipopeptide compositions and related methods 23 Nov, 2030
(6 years from now)
Active

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Cubicin Rf's drug page


3. Dificid

Dificid is protected by 13 patents, out of which 3 have expired. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US9808530
(Pediatric)
Composition of tiacumicin compounds 28 Nov, 2034
(10 years from now)
Active
US9808530 Composition of tiacumicin compounds 28 May, 2034
(9 years from now)
Active
US7378508
(Pediatric)
Polymorphic crystalline forms of tiacumicin B 31 Jan, 2028
(3 years from now)
Active
US7863249
(Pediatric)
Macrolide polymorphs, compositions comprising such polymorphs, and methods of use and manufacture thereof 31 Jan, 2028
(3 years from now)
Active
US8859510
(Pediatric)
Macrocyclic polymorphs, compositions comprising such polymorphs, and methods of use and manufacture thereof 31 Jan, 2028
(3 years from now)
Active
US7906489
(Pediatric)
18-membered macrocycles and analogs thereof 04 Sep, 2027
(2 years from now)
Active
US7378508 Polymorphic crystalline forms of tiacumicin B 31 Jul, 2027
(2 years from now)
Active
US7863249 Macrolide polymorphs, compositions comprising such polymorphs, and methods of use and manufacture thereof 31 Jul, 2027
(2 years from now)
Active
US8859510 Macrocyclic polymorphs, compositions comprising such polymorphs, and methods of use and manufacture thereof 31 Jul, 2027
(2 years from now)
Active
US7906489 18-membered macrocycles and analogs thereof 04 Mar, 2027
(2 years from now)
Active
US8586551
(Pediatric)
18-membered macrocycles and analogs thereof 15 Jan, 2024
(10 months ago)
Expired
US8586551 18-membered macrocycles and analogs thereof 23 Jul, 2023
(1 year, 4 months ago)
Expired
US8586551 18-membered macrocycles and analogs thereof 15 Jul, 2023
(1 year, 4 months ago)
Expired

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Dificid's drug page


4. Sivextro

Sivextro is protected by 7 patents, out of which none have expired yet. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US8426389 Crystalline form of R)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate 31 Dec, 2030
(6 years from now)
Active
US10065947 Forms of R)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate 03 Feb, 2030
(5 years from now)
Active
US10442829 Forms of R)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate 03 Feb, 2030
(5 years from now)
Active
US9624250 Forms of R)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate 03 Feb, 2030
(5 years from now)
Active
US9988406 Forms of R)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate 03 Feb, 2030
(5 years from now)
Active
US7816379 Oxazolidinone derivatives 20 Jun, 2028
(3 years from now)
Active
US8420676 Oxazolidinone derivatives 23 Feb, 2028
(3 years from now)
Active

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Sivextro's drug page


5. Zerbaxa

Zerbaxa is protected by 14 patents, out of which none have expired yet. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US10125149 Synthesis of cephalosporin compounds 14 Aug, 2035
(10 years from now)
Active
US10376496 Treating infections with ceftolozane/tazobactam in subjects having impaired renal function 09 Sep, 2034
(9 years from now)
Active
US10933053 Treating infections with ceftolozane/tazobactam in subjects having impaired renal function 09 Sep, 2034
(9 years from now)
Active
US8906898 Solid forms of ceftolozane 28 May, 2034
(9 years from now)
Active
US10420841 Ceftolozane antibiotic compositions 14 Mar, 2034
(9 years from now)
Active
US11278622 Ceftolozane antibiotic compositions 14 Mar, 2034
(9 years from now)
Active
US8968753 Ceftolozane-tazobactam pharmaceutical compositions 14 Mar, 2034
(9 years from now)
Active
US9320740 Ceftolozane-tazobactam pharmaceutical compositions 14 Mar, 2034
(9 years from now)
Active
US9872906 Ceftolozane antibiotic compositions 14 Mar, 2034
(9 years from now)
Active
US8476425 Tazobactam arginine compositions 27 Sep, 2032
(7 years from now)
Active
US8685957 Tazobactam arginine compositions 27 Sep, 2032
(7 years from now)
Active
US10028963 Methods for treating intrapulmonary infections 07 Sep, 2032
(7 years from now)
Active
US9724353 Methods for treating intrapulmonary infections 07 Sep, 2032
(7 years from now)
Active
US7129232 Cephem compounds 15 May, 2028
(3 years from now)
Active

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Zerbaxa's drug page


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