Musculoskeletal Therapeutics

1. Bextra patent expiration

Treatment: Signs and symptoms of osteoarthritis and adult rheumatoid arthritis and treatment of primary dysmenorrhea

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US5633272 GD SEARLE Substituted isoxazoles for the treatment of inflammation
Feb, 2015

(10 years ago)




Drugs and Companies using VALDECOXIB ingredient

Market Authorisation Date: 16 November, 2001

Dosage: TABLET

More Information on Dosage

BEXTRA family patents

Family Patents

2. Boniva patent expiration

Treatment: Treatment and prevention of osteoporosis; Treatment and prevention of osteoporosis in postmenopausal women by once-monthly oral administration of ibandronate sodium monohydrate equivalent to 150mg of ...

BONIVA's oppositions filed in EPO
Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US6143326 HOFFMANN LA ROCHE Oral pharmaceutical preparation containing ibandronat
Apr, 2017

(8 years ago)

US7718634 HOFFMANN LA ROCHE Method of treatment using bisphosphonic acid
May, 2023

(2 years ago)

US6294196 HOFFMANN LA ROCHE Pharmaceutical composition containing diphosphonic acid or salt thereof
Oct, 2019

(6 years ago)

US7410957 HOFFMANN LA ROCHE Method of treatment using bisphosphonic acid
May, 2023

(2 years ago)

US7192938 HOFFMANN LA ROCHE Method of treatment using bisphosphonic acid
May, 2023

(2 years ago)




Drugs and Companies using IBANDRONATE SODIUM ingredient

Market Authorisation Date: 16 May, 2003

Dosage: TABLET

How can I launch a generic of BONIVA before it's drug patent expiration?
More Information on Dosage

BONIVA family patents

Family Patents

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3. Boniva patent expiration

Treatment: NA

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US5662918 ROCHE Pharmaceutical agents containing diphosphonic acids and salts thereof
Sep, 2014

(11 years ago)




Drugs and Companies using IBANDRONATE SODIUM ingredient

Market Authorisation Date: 06 January, 2006

Dosage: INJECTABLE

How can I launch a generic of BONIVA before it's drug patent expiration?
More Information on Dosage

BONIVA family patents

Family Patents

4. Cymbalta patent expiration

Treatment: Management of fibromyalgia (fm); Method of treating anxiety

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US6596756

(Pediatric)

LILLY Treatment of fibromyalgia
Mar, 2020

(5 years ago)

US5508276 LILLY Duloxetine enteric pellets
Jul, 2014

(11 years ago)

US6596756 LILLY Treatment of fibromyalgia
Sep, 2019

(6 years ago)

US5023269 LILLY 3-aryloxy-3-substituted propanamines
Jun, 2013

(12 years ago)

US5023269

(Pediatric)

LILLY 3-aryloxy-3-substituted propanamines
Dec, 2013

(12 years ago)

US5508276

(Pediatric)

LILLY Duloxetine enteric pellets
Jan, 2015

(10 years ago)




Drug Exclusivity Drug Exclusivity Expiration
New Indication(I-617) Nov 19, 2012
New Indication(I-632) Nov 04, 2013
Pediatric Exclusivity(PED) Apr 18, 2016
M(M-61) Oct 18, 2015
New Patient Population(NPP) Apr 20, 2023

Drugs and Companies using DULOXETINE HYDROCHLORIDE ingredient

Market Authorisation Date: 03 August, 2004

Dosage: CAPSULE, DELAYED REL PELLETS

How can I launch a generic of CYMBALTA before it's drug patent expiration?
More Information on Dosage

CYMBALTA family patents

Family Patents

5. Qutenza patent expiration

Treatment: Method of using capsaicin in combination with a gel composition for removal of capsaicin from a treatment area or unintended area

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US8263059 AVERITAS Compositions and kits for the removal of irritating compounds from bodily surfaces
Sep, 2023

(2 years ago)

US10869827 AVERITAS Compositions and kits for the removal of irritating compounds from bodily surfaces
Sep, 2023

(2 years ago)

US6239180 AVERITAS Transdermal therapeutic device and method with capsaicin and capsaicin analogs
Nov, 2016

(9 years ago)

US8889113 AVERITAS Compositions and kits for the removal of irritating compounds from bodily surfaces
Sep, 2023

(2 years ago)

US10463598 AVERITAS Compositions and kits for the removal of irritating compounds from bodily surfaces
Sep, 2023

(2 years ago)

US9226903 AVERITAS Transdermal therapeutic system comprising an adhesive layer method for siliconizing the back layer or the system and use of said back layer
Dec, 2028

(2 years from now)

US10034841 AVERITAS Transdermal therapeutic system comprising an adhesive layer method for siliconizing the back layer of the system and use of said back layer
Sep, 2025

(4 months ago)

US8821920 AVERITAS Therapeutic patch for transdermal delivery of capsaicin
Mar, 2030

(4 years from now)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Nov 16, 2014
Orphan Drug Exclusivity(ODE) Nov 16, 2016
New Indication(I-838) Jul 17, 2023

Drugs and Companies using CAPSAICIN ingredient

NCE-1 date: 16 November, 2013

Market Authorisation Date: 16 November, 2009

Dosage: PATCH

More Information on Dosage

QUTENZA family patents

Family Patents

6. Sohonos patent expiration

Treatment: Reduction of heterotopic ossification in patients with fibrodysplasia (myositis) ossificans progressiva; Reduction of heterotopic ossification in patients with fibrodysplasia ossificans (myositis) pro...

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US11622959 IPSEN Methods for treating heterotopic ossification
Jun, 2037

(11 years from now)

US10864194 IPSEN Methods for treating heterotopic ossification
Jun, 2037

(11 years from now)

US10292954 IPSEN Composition and method for muscle repair and regeneration
Aug, 2031

(5 years from now)

US9789074 IPSEN Composition and method for muscle repair and regeneration
Aug, 2031

(5 years from now)

US9314439 IPSEN Composition and method for muscle repair and regeneration
Aug, 2031

(5 years from now)

US12023312 IPSEN Composition and method for muscle repair and regeneration
Aug, 2031

(5 years from now)

US12201614 IPSEN Methods for treating heterotopic ossification
Jun, 2037

(11 years from now)

US12458626 IPSEN NA
Jun, 2037

(11 years from now)

US12138245 IPSEN Methods for treating heterotopic ossification
Jun, 2037

(11 years from now)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Aug 16, 2028
Orphan Drug Exclusivity(ODE-439) Aug 16, 2030

Drugs and Companies using PALOVAROTENE ingredient

NCE-1 date: 17 August, 2027

Market Authorisation Date: 16 August, 2023

Dosage: CAPSULE

More Information on Dosage

SOHONOS family patents

Family Patents

7. Vioxx patent expiration

Treatment: Relief of the signs and symptoms of osteoarthritis; Relief of the signs and symptoms of rheumatoid arthritis in adults; Management of acute pain in adults; Treatment of primary dysmenorrhea; Acute tre...

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US5691374 MERCK Diaryl-5-oxygenated-2-(5H) -furanones as COX-2 inhibitors
May, 2015

(10 years ago)

US5474995

(Pediatric)

MERCK Phenyl heterocycles as cox-2 inhibitors
Dec, 2013

(12 years ago)

US6239173

(Pediatric)

MERCK 3-phenyl-4-(4(methylsulfonyl)phenyl)-2-(5H)-furanone as a cox-2 inhibitor
Dec, 2013

(12 years ago)

US5691374

(Pediatric)

MERCK Diaryl-5-oxygenated-2-(5H) -furanones as COX-2 inhibitors
Nov, 2015

(10 years ago)

US5474995 MERCK Phenyl heterocycles as cox-2 inhibitors
Jun, 2013

(12 years ago)

US6063811

(Pediatric)

MERCK Compositions for a once day treatment of cyclooxygenase-2 mediated diseases
Nov, 2017

(8 years ago)

US6239173 MERCK 3-phenyl-4-(4(methylsulfonyl)phenyl)-2-(5H)-furanone as a cox-2 inhibitor
Jun, 2013

(12 years ago)

US6063811 MERCK Compositions for a once day treatment of cyclooxygenase-2 mediated diseases
May, 2017

(8 years ago)




Drugs and Companies using ROFECOXIB ingredient

Market Authorisation Date: 20 May, 1999

Dosage: TABLET; SUSPENSION

How can I launch a generic of VIOXX before it's drug patent expiration?
More Information on Dosage

VIOXX family patents

Family Patents