Nelarabine Patent Expiration

Nelarabine is used for treating T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma that have not responded to or relapsed after two chemotherapy regimens. It was first introduced by Sandoz Inc in its drug Arranon on Oct 28, 2005. 11 different companies have introduced drugs containing Nelarabine.


Nelarabine Patents

Given below is the list of patents protecting Nelarabine, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Arranon US5424295 9-β-D-arabinofuranasyl-2-amino-6-methaoxy-9H-purine Jun 13, 2017

(Expired)

Sandoz
Arranon US5492897 Method for treating T-cell lymphoblastic leukemia with ara-G nucleoside derivatives Feb 20, 2013

(Expired)

Sandoz
Arranon US5747472 Therapeutic methods for using ARA-G derivatives Feb 20, 2013

(Expired)

Sandoz
Arranon US5821236 Tumor treatment with arabinofuranosyl purine derivatives Feb 20, 2013

(Expired)

Sandoz



Nelarabine's Family Patents

Family Patents

Explore Our Curated Drug Screens

Drugs Generating Over $1 Billion in Annual Revenue
Explore the top-performing drugs that dominate the pharmaceutical industry
View List
NCE-1 Patent Expiry in the Next 1 Year
Identify opportunities as new chemical entity (NCE-1) patents approach expiry
View List
Recently Granted Patents in EP
Find the opportunity to file Oppositions
View List

Nelarabine Generic API Manufacturers

Several generic applications have been filed for Nelarabine. The first generic version for Nelarabine was by Zydus Pharmaceuticals Usa Inc and was approved on Nov 17, 2021. And the latest generic version is by Shorla Pharma Ltd and was approved on Jul 16, 2025.

Given below is the list of companies who have filed for Nelarabine generic, along with the locations of their manufacturing plants worldwide.