Naproxen Patent Expiration

Naproxen was first introduced by Atnahs Pharma Us Ltd in its drug Naprosyn on Approved Prior to Jan 1, 1982. Another drug containing Naproxen is Ec-Naprosyn. 32 different companies have introduced drugs containing Naproxen.


About Veterinary Naproxen

Naproxen is used in a drug marketed by 1 company: Zoetis Inc.

Other drugs containing Naproxen are: Equiproxen 10% solution , Equiproxen granules .

Naproxen's Family Patents

Family Patents

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Clinical Trials

Recent Clinical Trials on Naproxen:

Sometimes companies keep conducting clinical trials even after the drug's approval to discover new formulations, methods of use, or new treatment indications, so they could file for additional patents or receive regulatory exclusivity extensions, such as pediatric exclusivity, potentially delaying generic competition. Based on these recent clinical trials, generic companies need to consider the potential for new intellectual property or regulatory hurdles. These strategic moves by the drug owner might delay generic substitution or lead to additional sales of the brand drug, even after patent expiry.

Title Lead Sponsor Collaborators Status Phases
Clinical Trials
Efficacy and Safety of Rizatriptan-Naproxen (10/550 mg) in the Acute Treatment of Migraine Eurofarma Laboratorios S.A. NA COMPLETED
(Sep 1, 2026)
PHASE3
NSAIDS Following Elective Lumbar Spine Fusion Rothman Institute Orthopaedics NA ENROLLING BY INVITATION
(Jul 1, 2026)
PHASE3
PK,PD and DDI of Epaminurad and Naproxen in Healthy Volunteers JW Pharmaceutical NA COMPLETED
(Mar 1, 2026)
PHASE1
A Study of SJP-001 in Comparison With Fexofenadine and Naproxen Administered With Alcohol Sen-Jam Pharmaceutical NA COMPLETED
(Mar 1, 2026)
PHASE1, PHASE2


Naproxen Generic API Manufacturers

Several generic applications have been filed for Naproxen. The first generic version for Naproxen was by Hamilton Pharmaceuticals Ltd and was approved on Oct 30, 1992. And the latest generic version is by Aurobindo Pharma Ltd and was approved on Oct 3, 2025.

Given below is the list of companies who have filed for Naproxen generic, along with the locations of their manufacturing plants worldwide.