Nalmefene Hydrochloride is Used for reversing opioid overdose. It was first introduced by Hikma Pharmaceuticals Usa Inc in its drug Revex on Apr 17, 1995. Other drugs containing Nalmefene Hydrochloride are Opvee, Zurnai (Autoinjector). 4 different companies have introduced drugs containing Nalmefene Hydrochloride.

Nalmefene Hydrochloride Patents

Given below is the list of patents protecting Nalmefene Hydrochloride, along with the drug name that holds that patent and the company name owning that drug.

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Drug Used in	Drug Patent Number	Drug Patent Title	Drug Patent Expiry	Drug Owner
Opvee	US12290596	Compositions and methods for the treatment of opioid overdose	Aug 04, 2042	Indivior
Zurnai (autoinjector)	US11857547	Compositions and methods for opioid antagonist delivery	Nov 05, 2039	Purdue Pharma Lp
Zurnai (autoinjector)	US11865112	Compositions and methods for opioid antagonist delivery	Nov 05, 2039	Purdue Pharma Lp
Opvee	US11458091	Compositions and methods for the treatment of opioid overdose	Jul 10, 2038	Indivior
Zurnai (autoinjector)	US11191908	Syringe shock absorber for use in an injection device	Oct 18, 2035	Purdue Pharma Lp
Zurnai (autoinjector)	US11813435	Needle assisted injection device having reduced trigger force	Feb 25, 2035	Purdue Pharma Lp
Zurnai (autoinjector)	US10881798	Needle assisted injection device having reduced trigger force	Feb 11, 2034	Purdue Pharma Lp
Zurnai (autoinjector)	US11185642	Injection device with cammed ram assembly	Aug 28, 2031	Purdue Pharma Lp
Zurnai (autoinjector)	US10357609	Needle assisted jet injection device having reduced trigger force	Aug 21, 2031	Purdue Pharma Lp
Zurnai (autoinjector)	US10905827	Injection device with cammed ram assembly	Aug 21, 2031	Purdue Pharma Lp
Zurnai (autoinjector)	US11446440	Needle assisted injection device having reduced trigger force	Aug 21, 2031	Purdue Pharma Lp
Zurnai (autoinjector)	US8496619	Injection device with cammed ram assembly	Aug 21, 2031	Purdue Pharma Lp
Zurnai (autoinjector)	US9364610	Injection device with cammed ram assembly	Aug 21, 2031	Purdue Pharma Lp
Zurnai (autoinjector)	US9364611	Needle assisted jet injection device having reduced trigger force	Aug 21, 2031	Purdue Pharma Lp
Zurnai (autoinjector)	US9446195	Injection device with cammed ram assembly	Aug 21, 2031	Purdue Pharma Lp
Zurnai (autoinjector)	US10279131	Injection device with cammed RAM assembly	Jul 31, 2031	Purdue Pharma Lp
Zurnai (autoinjector)	US8021335	Prefilled syringe jet injector	Oct 04, 2026	Purdue Pharma Lp
Zurnai (autoinjector)	US10478560	Prefilled syringe injector	Jan 24, 2026	Purdue Pharma Lp
Zurnai (autoinjector)	US11446441	Prefilled syringe injector	Jan 24, 2026	Purdue Pharma Lp
Zurnai (autoinjector)	US8562564	Prefilled syringe jet injector	Jan 24, 2026	Purdue Pharma Lp
Zurnai (autoinjector)	US9180259	Prefilled syringe jet injector	Jan 24, 2026	Purdue Pharma Lp
Zurnai (autoinjector)	US9533102	Prefilled syringe jet injector	Jan 24, 2026	Purdue Pharma Lp
Zurnai (autoinjector)	US9629959	Prefilled syringe jet injector	Jan 24, 2026	Purdue Pharma Lp

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Nalmefene Hydrochloride's Family Patents

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Nalmefene Hydrochloride Generic API Manufacturers

Several generic applications have been filed for Nalmefene Hydrochloride. The first generic version for Nalmefene Hydrochloride was by Purdue Pharma Lp and was approved on Feb 8, 2022. And the latest generic version is by Chengdu Shuode Pharmaceutical Co Ltd and was approved on Nov 15, 2023.

Given below is the list of companies who have filed for Nalmefene Hydrochloride generic, along with the locations of their manufacturing plants worldwide.