Methylnaltrexone Bromide Patent Expiration

Methylnaltrexone Bromide is Used for managing opioid-induced constipation. It was first introduced by Salix Pharmaceuticals Inc in its drug Relistor on Apr 24, 2008. 2 different companies have introduced drugs containing Methylnaltrexone Bromide.


Methylnaltrexone Bromide Patents

Given below is the list of patents protecting Methylnaltrexone Bromide, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Relistor US10307417 Oral formulations and lipophilic salts of methylnaltrexone Mar 10, 2031 Salix
Relistor US10376505 Oral formulations and lipophilic salts of methylnaltrexone Mar 10, 2031 Salix
Relistor US10376584 Stable pharmaceutical formulations of methylnaltrexone Apr 08, 2024

(Expired)

Salix Pharms
Relistor US6559158 Use of methylnaltrexone and related compounds to treat chronic opioid use side affects Nov 03, 2017

(Expired)

Salix
Relistor US6559158 Use of methylnaltrexone and related compounds to treat chronic opioid use side affects Nov 03, 2017

(Expired)

Salix Pharms
Relistor US8247425 Peripheral opioid receptor antagonists and uses thereof Dec 31, 2030 Salix Pharms
Relistor US8420663 Peripheral opioid receptor antagonists and uses thereof Sep 30, 2029 Salix
Relistor US8420663 Peripheral opioid receptor antagonists and uses thereof Sep 30, 2029 Salix Pharms
Relistor US8524276 Oral formulations and lipophilic salts of methylnaltrexone Mar 10, 2031 Salix
Relistor US8552025 Stable methylnaltrexone preparation Apr 08, 2024

(Expired)

Salix Pharms
Relistor US8822490 Peripheral opioid receptor antagonists and uses thereof Sep 30, 2029 Salix Pharms
Relistor US8956651 Oral formulations and lipophilic salts of methylnal trexone Mar 10, 2031 Salix
Relistor US9180125 Peripheral opioid receptor antagonists and uses thereof Sep 30, 2029 Salix
Relistor US9180125 Peripheral opioid receptor antagonists and uses thereof Sep 30, 2029 Salix Pharms
Relistor US9314461 Oral formulations and lipophilic salts of methylnaltrexone Mar 10, 2031 Salix
Relistor US9492445 Peripheral opioid receptor antagonists and uses thereof Sep 30, 2029 Salix
Relistor US9492445 Peripheral opioid receptor antagonists and uses thereof Sep 30, 2029 Salix Pharms
Relistor US9669096 Stable pharmaceutical formulations of methylnaltrexone Apr 08, 2024

(Expired)

Salix Pharms
Relistor US9724343 Peripheral opioid receptor antagonists and uses thereof Sep 30, 2029 Salix


A patent's expiry date may change depending upon legal activities going on that patent. Critical activities like abandoning of a patent, term extension of a patent or amendment of its claims can increase or decrease the life of a patent hence affecting its expiry date and in turn affecting the generic launch date of that drug. Tracking these ongoing activities on a patent application helps to keep an eye on the latest developments in the patent process of the drug which can give an idea of how early a drug's generic could be available. The next section provides a list of recent legal activities on Methylnaltrexone Bromide's patents.

Given below is the list recent legal activities going on the following patents of Methylnaltrexone Bromide.

Event Date Patent/Publication
Patent litigations
Payment of Maintenance Fee, 12th Year, Large Entity 23 Jan, 2024 US8247425
Payment of Maintenance Fee, 8th Year, Large Entity 20 Sep, 2023 US9314461
Payment of Maintenance Fee, 8th Year, Large Entity 20 Apr, 2023 US9180125
Payment of Maintenance Fee, 4th Year, Large Entity 20 Jan, 2023 US10376505
Payment of Maintenance Fee, 4th Year, Large Entity 20 Jan, 2023 US10376584
Payment of Maintenance Fee, 4th Year, Large Entity 16 Nov, 2022 US10307417
Payment of Maintenance Fee, 8th Year, Large Entity 20 Jul, 2022 US8956651
Payment of Maintenance Fee, 8th Year, Large Entity 23 Feb, 2022 US8822490
Payment of Maintenance Fee, 8th Year, Large Entity 29 Mar, 2021 US8552025(Litigated)
Payment of Maintenance Fee, 8th Year, Large Entity 24 Feb, 2021 US8524276



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