Ketorolac Tromethamine Patent Expiration

Ketorolac Tromethamine was first introduced by Roche Palo Alto Llc in its drug Toradol on Nov 30, 1989. Other drugs containing Ketorolac Tromethamine are Acular, Sprix, Acular Preservative Free, Acular Ls, Acuvail. 39 different companies have introduced drugs containing Ketorolac Tromethamine.


Ketorolac Tromethamine Patents

Given below is the list of patents protecting Ketorolac Tromethamine, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Acuvail US7842714 Ketorolac tromethamine compositions for treating ocular pain Aug 15, 2029 Abbvie
Acuvail US8512717 Compositions for delivery of therapeutics into the eyes and methods for making and using same Mar 07, 2028 Abbvie
Acuvail US9192571 Ketorolac tromethamine compositions for treating or preventing ocular pain Mar 07, 2028 Abbvie
Acular Ls US8008338

(Pediatric)

Ketorolac tromethamine compositions for treating or preventing ocular pain Nov 24, 2027 Abbvie
Acular Ls US8008338 Ketorolac tromethamine compositions for treating or preventing ocular pain May 24, 2027 Abbvie
Acular Ls US8207215

(Pediatric)

Ketorolac tromethamine compositions for treating or preventing ocular pain Nov 28, 2024

(Expired)

Abbvie
Acular Ls US8377982

(Pediatric)

Ketorolac tromethamine compositions for treating or preventing ocular pain Nov 28, 2024

(Expired)

Abbvie
Acular Ls US8541463

(Pediatric)

Ketorolac tromethamine compositions for treating or preventing ocular pain Nov 28, 2024

(Expired)

Abbvie
Acuvail US8992952 Compositions for delivery of therapeutics into the eyes and methods for making and using same Aug 05, 2024

(Expired)

Abbvie
Acular Ls US8207215 Ketorolac tromethamine compositions for treating or preventing ocular pain May 28, 2024

(Expired)

Abbvie
Acular Ls US8377982 Ketorolac tromethamine compositions for treating or preventing ocular pain May 28, 2024

(Expired)

Abbvie
Acular Ls US8541463 Ketorolac tromethamine compositions for treating or preventing ocular pain May 28, 2024

(Expired)

Abbvie
Acular Ls US8648107 Ketorolac tromethamine compositions for treating or preventing ocular pain May 28, 2024

(Expired)

Abbvie
Acular Ls US8906950 Ketorolac tromethamine compositions for treating or preventing ocular pain May 28, 2024

(Expired)

Abbvie
Acular Ls US8946281 Ketorolac tromethamine compositions for treating or preventing ocular pain May 28, 2024

(Expired)

Abbvie
Acular Ls US9216127 Burial vault and method for customizing a burial vault May 28, 2024

(Expired)

Abbvie
Acular Ls US9216167 Ketorolac tromethamine compositions for treating or preventing ocular pain May 28, 2024

(Expired)

Abbvie
Sprix US6333044 Therapeutic compositions for intranasal administration which include KETOROLAC® Dec 25, 2018

(Expired)

Zyla
Sprix US7476689 Therapeutic compositions for intranasal administration which include KETOROLAC Oct 11, 2012

(Expired)

Zyla



A patent's expiry date may change depending upon legal activities going on that patent. Critical activities like abandoning of a patent, term extension of a patent or amendment of its claims can increase or decrease the life of a patent hence affecting its expiry date and in turn affecting the generic launch date of that drug. Tracking these ongoing activities on a patent application helps to keep an eye on the latest developments in the patent process of the drug which can give an idea of how early a drug's generic could be available. The next section provides a list of recent legal activities on Ketorolac Tromethamine's patents.

Given below is the list recent legal activities going on the following patents of Ketorolac Tromethamine.

Activity Date Patent Number
Patent litigations
Expire Patent 10 Feb, 2017 US7476689
Correspondence Address Change 27 Oct, 2010 US7476689
Recordation of Patent Grant Mailed 13 Jan, 2009 US7476689
Patent Issue Date Used in PTA Calculation 13 Jan, 2009 US7476689
Issue Notification Mailed 22 Dec, 2008 US7476689
Dispatch to FDC 15 Dec, 2008 US7476689
Printer Rush- No mailing 05 Dec, 2008 US7476689
Pubs Case Remand to TC 13 Nov, 2008 US7476689
Printer Rush- No mailing 05 Nov, 2008 US7476689
Pubs Case Remand to TC 29 Sep, 2008 US7476689


Ketorolac Tromethamine's Family Patents

Family Patents

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Ketorolac Tromethamine Generic API Manufacturers

Several generic applications have been filed for Ketorolac Tromethamine. The first generic version for Ketorolac Tromethamine was by Teva Pharmaceuticals Usa Inc and was approved on May 16, 1997. And the latest generic version is by Caplin Steriles Ltd and was approved on Mar 26, 2024.

Given below is the list of companies who have filed for Ketorolac Tromethamine generic, along with the locations of their manufacturing plants worldwide.