Imatinib Mesylate Patent Expiration

Imatinib Mesylate is Used for treating tumors and gastrointestinal stromal tumors (GIST) in patients with CD117 positive unresectable or metastatic disease. It was first introduced by Novartis Pharmaceuticals Corp in its drug Gleevec on May 10, 2001. Another drug containing Imatinib Mesylate is Imkeldi. 18 different companies have introduced drugs containing Imatinib Mesylate.


Imatinib Mesylate Patents

Given below is the list of patents protecting Imatinib Mesylate, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Imkeldi US11957681 Liquid dosage forms of Imatinib Apr 27, 2040 Shorla Oncology
Gleevec US6958335

(Pediatric)

Treatment of gastrointestinal stromal tumors Jun 19, 2022

(Expired)

Novartis
Gleevec US6958335 Treatment of gastrointestinal stromal tumors Dec 19, 2021

(Expired)

Novartis
Gleevec US6894051

(Pediatric)

Crystal modification of a N-phenyl-2-pyrimidineamine derivative, processes for its manufacture and its use Nov 23, 2019

(Expired)

Novartis
Gleevec US7544799

(Pediatric)

Crystal modification of a N-phenyl-2-pyrimidineamine derivative, processes for its manufacture and its use Jul 16, 2019

(Expired)

Novartis
Gleevec USRE43932

(Pediatric)

Crystal modification of a N-phenyl-2-pyrimidineamine derivative, processes for its manufacture and its use Jul 16, 2019

(Expired)

Novartis
Gleevec US6894051 Crystal modification of a N-phenyl-2-pyrimidineamine derivative, processes for its manufacture and its use May 23, 2019

(Expired)

Novartis
Gleevec US7544799 Crystal modification of a N-phenyl-2-pyrimidineamine derivative, processes for its manufacture and its use Jan 16, 2019

(Expired)

Novartis
Gleevec USRE43932 Crystal modification of a N-phenyl-2-pyrimidineamine derivative, processes for its manufacture and its use Jan 16, 2019

(Expired)

Novartis
Gleevec USRE43932

(Pediatric)

Crystal modification of a N-phenyl-2-pyrimidineamine derivative, processes for its manufacture and its use Jan 16, 2019

(Expired)

Novartis
Gleevec USRE43932 Crystal modification of a N-phenyl-2-pyrimidineamine derivative, processes for its manufacture and its use Jul 16, 2018

(Expired)

Novartis
Gleevec US5521184

(Pediatric)

Pyrimidine derivatives and processes for the preparation thereof Jul 04, 2015

(Expired)

Novartis
Gleevec US5521184 Pyrimidine derivatives and processes for the preparation thereof Jan 04, 2015

(Expired)

Novartis



Imatinib Mesylate's Family Patents

Family Patents

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Imatinib Mesylate Generic API Manufacturers

Several generic applications have been filed for Imatinib Mesylate. The first generic version for Imatinib Mesylate was by Sun Pharmaceutical Industries Ltd and was approved on Dec 3, 2015. And the latest generic version is by Cspc Ouyi Pharmaceutical Co Ltd and was approved on Apr 21, 2025.

Given below is the list of companies who have filed for Imatinib Mesylate generic, along with the locations of their manufacturing plants worldwide.