Elexacaftor, Ivacaftor, Tezacaftor; Ivacaftor Patent Expiration

Elexacaftor, Ivacaftor, Tezacaftor; Ivacaftor is used for treating cystic fibrosis in patients with specific genetic mutations. It was first introduced by Vertex Pharmaceuticals Inc in its drug Trikafta (Copackaged) on Oct 21, 2019.


Elexacaftor, Ivacaftor, Tezacaftor; Ivacaftor Patents

Given below is the list of patents protecting Elexacaftor, Ivacaftor, Tezacaftor; Ivacaftor, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Trikafta (copackaged) US10793547 Modulator of the cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator Dec 08, 2037 Vertex Pharms Inc
Trikafta (copackaged) US11179367 Pharmaceutical compositions for treating cystic fibrosis Dec 08, 2037 Vertex Pharms Inc
Trikafta (copackaged) US11453655 Modulator of the cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator Dec 08, 2037 Vertex Pharms Inc
Trikafta (copackaged) US11517564 Methods of treatment for cystic fibrosis Dec 08, 2037 Vertex Pharms Inc
Trikafta (copackaged) US10758534 NA Oct 06, 2035 Vertex Pharms Inc
Trikafta (copackaged) US11426407 Modulators of cystic fibrosis transmembrane conductance regulator Oct 06, 2035 Vertex Pharms Inc
Trikafta (copackaged) US9012496 Pharmaceutical compositions of (R)-1-(2,2-difluorobenzo[D][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide and administration thereof Jul 15, 2033 Vertex Pharms Inc
Trikafta (copackaged) US10272046 Pharmaceutical composition and administrations thereof Feb 27, 2033 Vertex Pharms Inc
Trikafta (copackaged) US11147770 Pharmaceutical composition and administrations thereof Feb 27, 2033 Vertex Pharms Inc
Trikafta (copackaged) US11752106 Pharmaceutical composition and administrations thereof Feb 27, 2033 Vertex Pharms Inc
Trikafta (copackaged) US8883206 Pharmaceutical composition and administrations thereof Feb 27, 2033 Vertex Pharms Inc
Trikafta (copackaged) US10081621 Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide Mar 25, 2031 Vertex Pharms Inc
Trikafta (copackaged) US11578062 Solid forms of (R)-1(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide Mar 25, 2031 Vertex Pharms Inc
Trikafta (copackaged) US10646481 Pharmaceutical composition and administrations thereof Aug 13, 2029 Vertex Pharms Inc
Trikafta (copackaged) US11564916 Pharmaceutical composition and administrations thereof Aug 13, 2029 Vertex Pharms Inc
Trikafta (copackaged) US8415387 Modulators of ATP-binding cassette transporters Nov 12, 2027 Vertex Pharms Inc
Trikafta (copackaged) US8324242 Modulators of ATP-binding cassette transporters Aug 05, 2027 Vertex Pharms Inc
Trikafta (copackaged) US7776905 Modulators of ATP-binding cassette transporters Jun 03, 2027 Vertex Pharms Inc
Trikafta (copackaged) US7495103 Modulators of ATP-binding cassette transporters May 20, 2027 Vertex Pharms Inc
Trikafta (copackaged) US7645789 Indole derivatives as CFTR modulators May 01, 2027 Vertex Pharms Inc
Trikafta (copackaged) US8598181 Modulators of ATP-binding cassette transporters May 01, 2027 Vertex Pharms Inc
Trikafta (copackaged) US8623905 Modulators of ATP-binding cassette transporters May 01, 2027 Vertex Pharms Inc
Trikafta (copackaged) US10022352 Modulators of ATP-binding cassette transporters Apr 09, 2027 Vertex Pharms Inc
Trikafta (copackaged) US10239867 Modulators of ATP-binding cassette transporters Apr 09, 2027 Vertex Pharms Inc
Trikafta (copackaged) US11639347 Modulators of ATP-binding cassette transporters Apr 09, 2027 Vertex Pharms Inc
Trikafta (copackaged) US9974781 Modulators of ATP-binding cassette transporters Apr 09, 2027 Vertex Pharms Inc
Trikafta (copackaged) US8410274 Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide Dec 28, 2026 Vertex Pharms Inc
Trikafta (copackaged) US8754224 Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide Dec 28, 2026 Vertex Pharms Inc
Trikafta (copackaged) US9670163 Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide Dec 28, 2026 Vertex Pharms Inc
Trikafta (copackaged) US9931334 Solid forms of N[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide Dec 28, 2026 Vertex Pharms Inc
Trikafta (copackaged) US8354427 Modulators of ATP-binding cassette transporters Jul 06, 2026 Vertex Pharms Inc
Trikafta (copackaged) US8629162 Modulators of ATP-binding cassette transporters Jun 24, 2025 Vertex Pharms Inc



A patent's expiry date may change depending upon legal activities going on that patent. Critical activities like abandoning of a patent, term extension of a patent or amendment of its claims can increase or decrease the life of a patent hence affecting its expiry date and in turn affecting the generic launch date of that drug. Tracking these ongoing activities on a patent application helps to keep an eye on the latest developments in the patent process of the drug which can give an idea of how early a drug's generic could be available. The next section provides a list of recent legal activities on Elexacaftor, Ivacaftor, Tezacaftor; Ivacaftor's patents.

Given below is the list recent legal activities going on the following patents of Elexacaftor, Ivacaftor, Tezacaftor; Ivacaftor.

Activity Date Patent Number
Patent litigations
Payment of Maintenance Fee, 4th Year, Large Entity 08 Apr, 2024 US10793547
Payment of Maintenance Fee, 4th Year, Large Entity 01 Mar, 2024 US10758534
Electronic Review 24 May, 2023 US11578062
Post Issue Communication - Certificate of Correction 05 May, 2023 US11578062
Electronic Review 03 May, 2023 US11639347
Email Notification 03 May, 2023 US11639347
Patent Issue Date Used in PTA Calculation 02 May, 2023 US11639347
Miscellaneous Communication to Applicant - No Action Count 02 May, 2023 US11639347
Mail Miscellaneous Communication to Applicant 02 May, 2023 US11639347
Recordation of Patent eGrant 02 May, 2023 US11639347


Elexacaftor, Ivacaftor, Tezacaftor; Ivacaftor's Family Patents

Family Patents

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