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Divalproex Sodium Patent Expiration

Divalproex Sodium is Used for managing and preventing seizures in epilepsy and sometimes used for treating migraine headaches. It was first introduced by Abbvie Inc in its drug Depakote on Mar 10, 1983. Other drugs containing Divalproex Sodium are Depakote Er, Depakote Cp. 31 different companies have introduced drugs containing Divalproex Sodium.


Divalproex Sodium Patents

Given below is the list of patents protecting Divalproex Sodium, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Depakote Er US6419953

(Pediatric)

 Controlled release formulation of divalproex sodium Jun 18, 2019

(Expired)

 Abbvie
Depakote Er US6511678

(Pediatric)

 Controlled release formulation of divalproex sodium Jun 18, 2019

(Expired)

 Abbvie
Depakote Er US6528090

(Pediatric)

 Controlled release formulation of divalproex sodium Jun 18, 2019

(Expired)

 Abbvie
Depakote Er US6528091

(Pediatric)

 Controlled release formulation of divalproex sodium Jun 18, 2019

(Expired)

 Abbvie
Depakote Er US6713086

(Pediatric)

 Controlled release formulation of divalproex sodium Jun 18, 2019

(Expired)

 Abbvie
Depakote Er US6720004

(Pediatric)

 Controlled release formulation of divalproex sodium Jun 18, 2019

(Expired)

 Abbvie
Depakote Er US6419953 Controlled release formulation of divalproex sodium Dec 18, 2018

(Expired)

 Abbvie
Depakote Er US6511678 Controlled release formulation of divalproex sodium Dec 18, 2018

(Expired)

 Abbvie
Depakote Er US6528090 Controlled release formulation of divalproex sodium Dec 18, 2018

(Expired)

 Abbvie
Depakote Er US6528091 Controlled release formulation of divalproex sodium Dec 18, 2018

(Expired)

 Abbvie
Depakote Er US6713086 Controlled release formulation of divalproex sodium Dec 18, 2018

(Expired)

 Abbvie
Depakote Er US6720004 Controlled release formulation of divalproex sodium Dec 18, 2018

(Expired)

 Abbvie



Divalproex Sodium's Family Patents

Family Patents

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Divalproex Sodium Generic API Manufacturers

Several generic applications have been filed for Divalproex Sodium. The first generic version for Divalproex Sodium was by Teva Pharmaceuticals Usa Inc and was approved on Jul 29, 2008. And the latest generic version is by Annora Pharma Private Ltd and was approved on Sep 26, 2023.

Given below is the list of companies who have filed for Divalproex Sodium generic, along with the locations of their manufacturing plants worldwide.


1. ACTAVIS LABS FL INC

Actavis Laboratories Fl Inc has filed for 1 generic for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Actavis Labs Fl Inc.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 500MG VALPROIC ACID

tablet, delayed release Discontinued ORAL N/A Feb 25, 2011





2. AJANTA PHARMA LTD

Ajanta Pharma Ltd has filed for 1 generic for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Ajanta Pharma Ltd.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 125MG VALPROIC ACID

capsule, delayed rel pellets Prescription ORAL AB Mar 2, 2020


Manufacturing Plant Locations
New

Ajanta Pharma Ltd's manufacturing plants are situated in 1 country - India. Given below are the details of these plant locations as well as the firm names of Ajanta Pharma Ltd as present at those locations.

Country City Firm Name
India
Aurangabad Ajanta Pharma Ltd.





3. AMNEAL PHARMS

Amneal Pharmaceuticals has filed for 2 different strengths of generic version for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Amneal Pharms.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 500MG VALPROIC ACID

(reference standard)

tablet, extended release Prescription ORAL AB May 29, 2015
EQ 250MG VALPROIC ACID

tablet, extended release Prescription ORAL AB May 29, 2015





4. ANNORA PHARMA

Annora Pharma Private Ltd has filed for 2 different strengths of generic version for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Annora Pharma.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 500MG VALPROIC ACID

tablet, extended release Prescription ORAL AB Sep 26, 2023
EQ 250MG VALPROIC ACID

tablet, extended release Prescription ORAL AB Sep 26, 2023


Manufacturing Plant Locations
New

Annora Pharma's manufacturing plants are situated in 1 country - India. Given below are the details of these plant locations as well as the firm names of Annora Pharma as present at those locations.

Country City Firm Name
India
Hyderabad Annora Pharma Private Limited





5. APOTEX

Apotex Inc has filed for 3 different strengths of generic version for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Apotex.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 500MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Jul 29, 2008
EQ 250MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Jul 29, 2008
EQ 125MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Jul 29, 2008


Manufacturing Plant Locations
New

Apotex's manufacturing plants are situated in 3 countries - United States, Canada, India. Given below are the details of these plant locations as well as the firm names of Apotex as present at those locations.

Country City Firm Name
United States
Weston Apotex Corp.
Canada
Brantford Apotex Pharmachem Inc.
Winnipeg Apotex Fermentation Inc.
Etobicoke Apotex, Inc.
North York Apotex Inc.
Richmond Hill Apotex Inc.
Toronto Apotex Inc.
India
Bangalore Apotex Research Private Limited - Bioequivalence Centre
Bengaluru Apotex Research Private Limited
Bangalore Apotex Pharmachem India Pvt Ltd.





6. AUROBINDO PHARMA LTD

Aurobindo Pharma Ltd has filed for 3 different strengths of generic version for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Aurobindo Pharma Ltd.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 500MG VALPROIC ACID

tablet, extended release Prescription ORAL AB Jun 2, 2014
EQ 125MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Apr 21, 2011
EQ 250MG VALPROIC ACID

tablet, extended release Prescription ORAL AB Jun 2, 2014


Manufacturing Plant Locations
New

Aurobindo Pharma Ltd's manufacturing plants are situated in 1 country - India. Given below are the details of these plant locations as well as the firm names of Aurobindo Pharma Ltd as present at those locations.

Country City Firm Name
India
Medchal Aurobindo Pharma Ltd





7. CHARTWELL RX

Chartwell Rx Sciences Llc has filed for 3 different strengths of generic version for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Chartwell Rx.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 125MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Jul 31, 2008
EQ 500MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Jul 31, 2008
EQ 250MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Jul 31, 2008





8. COSETTE

Cosette Pharmaceuticals Inc has filed for 1 generic for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Cosette.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 500MG VALPROIC ACID

tablet, extended release Discontinued ORAL N/A Aug 3, 2009


Manufacturing Plant Locations
New

Cosette's manufacturing plants are situated in 1 country - United States. Given below are the details of these plant locations as well as the firm names of Cosette as present at those locations.

Country City Firm Name
United States
Lincolnton Cosette Pharmaceuticals NC Laboratories, LLC
South Plainfield Cosette Pharmaceuticals, Inc.





9. DR REDDYS LABS LTD

Dr Reddys Laboratories Ltd has filed for 3 different strengths of generic version for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Dr Reddys Labs Ltd.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 125MG VALPROIC ACID

capsule, delayed rel pellets Prescription ORAL AB Jan 23, 2009
EQ 250MG VALPROIC ACID

tablet, extended release Prescription ORAL AB Mar 15, 2012
EQ 500MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Jul 29, 2008





10. ENDO OPERATIONS

Endo Operations Ltd has filed for 2 different strengths of generic version for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Endo Operations.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 500MG VALPROIC ACID

tablet, extended release Discontinued ORAL N/A Aug 4, 2009
EQ 250MG VALPROIC ACID

tablet, extended release Discontinued ORAL N/A Feb 26, 2009





11. IMPAX LABS

Impax Laboratories Inc has filed for 2 different strengths of generic version for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Impax Labs.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 250MG VALPROIC ACID

tablet, extended release Discontinued ORAL N/A May 6, 2009
EQ 500MG VALPROIC ACID

tablet, extended release Discontinued ORAL N/A Aug 4, 2009





12. INVATECH

Invatech Pharma Solutions Llc has filed for 3 different strengths of generic version for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Invatech.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 500MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Jul 29, 2008
EQ 250MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Jul 29, 2008
EQ 125MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Jul 29, 2008


Manufacturing Plant Locations
New

Invatech's manufacturing plants are situated in 1 country - United States. Given below are the details of these plant locations as well as the firm names of Invatech as present at those locations.

Country City Firm Name
United States
East Brunswick InvaTech Pharma Solutions, LLC





13. LUPIN

Lupin Ltd has filed for 3 different strengths of generic version for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Lupin.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 125MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Jul 29, 2008
EQ 250MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Jul 29, 2008
EQ 500MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Jul 29, 2008


Manufacturing Plant Locations
New

Lupin's manufacturing plants are situated in 2 countries - India, United States. Given below are the details of these plant locations as well as the firm names of Lupin as present at those locations.

Country City Firm Name
India
Mumbai Lupin Limited
Pune Lupin Bioresearch Center
Vasco Da Gama Lupin Limited
Aurangabad Lupin Ltd.
Dabhasa LUPIN MANUFACTURING SOLUTIONS LIMITED
Pithampur Lupin Limited
Navi Mumbai LUPIN LIMITED
Mandideep Lupin Limited (Unit II)
Mandideep Lupin Limited
Nagpur Lupin Limited
Tarapur, Thane Lupin Limited
Pirangut Lupin Limited
Anakapalli District Lupin Manufacturing Solutions Limited
Pithampur Lupin Limited (Unit 1)
United States
Coral Springs Lupin Research Inc
Baltimore Lupin Pharmaceuticals Inc.





14. LUPIN LTD

Lupin Ltd has filed for 2 different strengths of generic version for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Lupin Ltd.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 500MG VALPROIC ACID

tablet, extended release Prescription ORAL AB Oct 18, 2019
EQ 250MG VALPROIC ACID

tablet, extended release Prescription ORAL AB Oct 18, 2019


Manufacturing Plant Locations
New

Lupin Ltd's manufacturing plants are situated in 1 country - India. Given below are the details of these plant locations as well as the firm names of Lupin Ltd as present at those locations.

Country City Firm Name
India
Aurangabad Lupin Ltd.





15. MYLAN

Mylan Pharmaceuticals Inc has filed for 3 different strengths of generic version for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Mylan.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 125MG VALPROIC ACID

tablet, delayed release Discontinued ORAL N/A Jul 29, 2008
EQ 250MG VALPROIC ACID

tablet, extended release Prescription ORAL AB Jan 29, 2009
EQ 500MG VALPROIC ACID

tablet, extended release Prescription ORAL AB Jan 29, 2009


Manufacturing Plant Locations
New

Mylan's manufacturing plants are situated in 4 countries - United States, India, Canada, Ireland. Given below are the details of these plant locations as well as the firm names of Mylan as present at those locations.

Country City Firm Name
United States
San Carlos Mylan Pharmaceuticals Inc.
Rockford Mylan Institutional, Inc.
Santa Barbara Mylandon LLC dba Debbie s Delights Santa Barbara Baking Co.
Morgantown Mylan Specialty, L.P.
Greensboro Mylan Pharmaceuticals Inc
Saint Albans Mylan Technologies, Inc.
Morgantown MYLAN CONSUMER HEALTHCARE Inc.
India
Sinnar Mylan Laboratories Limited
Aurangabad Mylan Laboratories Limited (FDF-2)
Hosur Mylan Laboratories Limited
Bangalore Mylan Laboratories Limited
Hyderabad Mylan Laboratories Limited
Sarigam Mylan Laboratories Limited
Pithampur, District Dhar Mylan Laboratories Limited
Anekal Taluk, Bangalore Mylan Laboratories Limited
Canada
Etobicoke Mylan Pharmaceuticals ULC
Ireland
Inverin Mylan Teoranta





16. NORVIUM BIOSCIENCE

Norvium Bioscience Llc has filed for 3 different strengths of generic version for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Norvium Bioscience.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 500MG VALPROIC ACID

tablet, delayed release Discontinued ORAL N/A Mar 17, 2009
EQ 250MG VALPROIC ACID

tablet, delayed release Discontinued ORAL N/A Mar 17, 2009
EQ 125MG VALPROIC ACID

tablet, delayed release Discontinued ORAL N/A Mar 17, 2009





17. ORBION PHARMS

Orbion Pharmaceuticals Private Ltd has filed for 3 different strengths of generic version for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Orbion Pharms.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 250MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Nov 25, 2008
EQ 125MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Nov 25, 2008
EQ 500MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Nov 25, 2008





18. PRINSTON INC

Prinston Pharmaceutical Inc has filed for 3 different strengths of generic version for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Prinston Inc.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 250MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Nov 30, 2009
EQ 500MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Nov 30, 2009
EQ 125MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Nov 30, 2009





19. REDDYS

Doctor Reddys Laboratories Ltd has filed for 1 generic for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Reddys.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 500MG VALPROIC ACID

tablet, extended release Prescription ORAL AB Mar 12, 2012





20. RISING

Rising Pharma Holding Inc has filed for 1 generic for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Rising.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 125MG VALPROIC ACID

capsule, delayed rel pellets Discontinued ORAL N/A Mar 28, 2011


Manufacturing Plant Locations
New

Rising's manufacturing plants are situated in 3 countries - United States, Mexico, India. Given below are the details of these plant locations as well as the firm names of Rising as present at those locations.

Country City Firm Name
United States
Flagstaff Rising High Enterprises, LLC (DBA RisingHy)
Rising Sun Rising Sun Veterinary Clinic
Fort Bragg Rising Tide Sea Vegetables
Mount Morris Rising Creek Bakery LLC
Decatur Rising Pharma Holdings, Inc
Saddle Brook Rising Pharmaceuticals, Inc.
East Brunswick Rising Pharma Holding, Inc.
Livingston Risingsun Iodine Products Corp.
Phoenix Rising Sun Farms Inc
Mexico
Pueblo San Clemente RISING FARMS SAPI DE CV
India
Ahmedabad Rising Retina Clinic





21. SUN PHARM INDS

Sun Pharmaceutical Industries Ltd has filed for 3 different strengths of generic version for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Sun Pharm Inds.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 125MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Jul 29, 2008
EQ 250MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Jul 29, 2008
EQ 500MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Jul 29, 2008





22. TEVA

Teva Pharmaceuticals Usa Inc has filed for 3 different strengths of generic version for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Teva.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 500MG VALPROIC ACID

tablet, delayed release Discontinued ORAL N/A Jul 29, 2008
EQ 125MG VALPROIC ACID

tablet, delayed release Discontinued ORAL N/A Jul 29, 2008
EQ 250MG VALPROIC ACID

tablet, delayed release Discontinued ORAL N/A Jul 29, 2008


Manufacturing Plant Locations
New

Teva's manufacturing plants are situated in 6 countries - United States, India, Canada, Czech Republic, Ireland, Israel. Given below are the details of these plant locations as well as the firm names of Teva as present at those locations.

Country City Firm Name
United States
Malvern Teva Branded Pharmaceutical Products R&D, Inc.
Miami Teva Branded Pharmaceutical Products R & D, Inc.
Horsham Teva Branded Pharmaceutical Products R&D
Fort Dodge TEVA Animal Health Inc
India
Gajraula, Amroha Teva API India Private Ltd.
Bhind Teva API India Ltd- Malanpur
Canada
Scarborough Teva Canada Limited
Markham Teva Canada Limited
Stouffville Teva Canada Limited
Czech Republic
Opava Teva Czech Industries s.r.o.
Ireland
Dundalk Teva Laboratories Ireland Ltd
Israel
Kiryat-Shmona TEVA Medical Ltd.





23. TEVA PHARMS USA

Teva Pharmaceuticals Usa Inc has filed for 1 generic for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Teva Pharms Usa.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 125MG VALPROIC ACID

capsule, delayed rel pellets Discontinued ORAL N/A Nov 17, 2020





24. UNICHEM

Unichem Laboratories Ltd has filed for 2 different strengths of generic version for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Unichem.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 250MG VALPROIC ACID

tablet, extended release Prescription ORAL AB Feb 25, 2022
EQ 500MG VALPROIC ACID

tablet, extended release Prescription ORAL AB Feb 25, 2022


Manufacturing Plant Locations
New

Unichem's manufacturing plants are situated in 2 countries - India, United States. Given below are the details of these plant locations as well as the firm names of Unichem as present at those locations.

Country City Firm Name
India
Pilerne Bardez Unichem Laboratories Limited
District Raigad Unichem Laboratories Ltd
Ghaziabad Unichem Laboratories Ltd.
Kolhapur Unichem Laboratories Limited
Mumbai Unichem Laboratories Limited
Pithampur Unichem Laboratories Limited
United States
East Brunswick Unichem Pharmaceuticals USA Inc.
Hasbrouck Heights Unichem Pharmaceuticals Usa Inc





25. UNICHEM LABS LTD

Unichem Laboratories Limited has filed for 3 different strengths of generic version for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Unichem Labs Ltd.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 125MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Apr 5, 2011
EQ 250MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Apr 5, 2011
EQ 500MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Apr 5, 2011





26. UPSHER SMITH LABS

Upsher Smith Laboratories Llc has filed for 3 different strengths of generic version for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Upsher Smith Labs.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 125MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Jul 29, 2008
EQ 250MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Jul 29, 2008
EQ 500MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Jul 29, 2008





27. UTOPIC PHARMS

Utopic Pharmaceuticals Inc has filed for 2 different strengths of generic version for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Utopic Pharms.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 250MG VALPROIC ACID

tablet, extended release Discontinued ORAL N/A Mar 15, 2021
EQ 500MG VALPROIC ACID

tablet, extended release Discontinued ORAL N/A Mar 15, 2021





28. WOCKHARDT

Wockhardt Ltd has filed for 2 different strengths of generic version for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Wockhardt.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 250MG VALPROIC ACID

tablet, extended release Prescription ORAL AB Feb 10, 2009
EQ 500MG VALPROIC ACID

tablet, extended release Prescription ORAL AB Aug 4, 2009


Manufacturing Plant Locations
New

Wockhardt's manufacturing plants are situated in 1 country - India. Given below are the details of these plant locations as well as the firm names of Wockhardt as present at those locations.

Country City Firm Name
India
Aurangabad Wockhardt Limited
Solan, Nalagarh Wockhardt Limited - Baddi
Ankleshwar Wockhardt, Ltd.





29. ZYDUS PHARMS USA INC

Zydus Pharmaceuticals Usa Inc has filed for 3 different strengths of generic version for Divalproex Sodium. Given below are the details of the strengths of this generic introduced by Zydus Pharms Usa Inc.

Strength Dosage Form Availability Application Pathway TE code Launch Date
EQ 125MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Mar 5, 2009
EQ 250MG VALPROIC ACID

tablet, delayed release Prescription ORAL AB Mar 5, 2009
EQ 500MG VALPROIC ACID

tablet, extended release Prescription ORAL AB Aug 4, 2009