Denosumab Patent Expiration
Denosumab Large Molecule Patents
Given below is the list of large molecule patents protecting Denosumab, along with the drug name that holds that patent and the company name owning that drug.
| Drug Used in | Drug Patent Number | Drug Patent Title | Drug Patent Expiry | Drug Owner |
|---|---|---|---|---|
| Prolia And Xgeva | USUS7364736 | Antibodies to OPGL | Feb 19, 2025 | Amgen Inc. |
| Prolia And Xgeva | USUS10513723 | Decreasing ornithine production to decrease high mannose glycoform content of recombinant proteins | Dec 09, 2034 | Amgen Inc. |
| Prolia And Xgeva | USUS10655156 | Overexpression of N-glycosylation pathway regulators to modulate glycosylation of recombinant proteins | Dec 11, 2034 | Amgen Inc. |
| Prolia And Xgeva | USUS10106829 | Overexpression of N-glycosylation pathway regulators to modulate glycosylation of recombinant proteins | Dec 11, 2034 | Amgen Inc. |
| Prolia And Xgeva | USUS11786866 | Process control systems and methods for use with filters and filtration processes | Oct 21, 2035 | Amgen Inc. |
| Prolia And Xgeva | USUS11319568 | Methods for increasing mannose content of recombinant proteins | Mar 10, 2034 | Amgen Inc. |
| Prolia And Xgeva | USUS9228168 | Feed media | Jan 19, 2030 | Amgen Inc. |
| Prolia And Xgeva | USUS11254963 | Increasing ornithine accumulation to increase high mannose glycoform content of recombinant proteins | Dec 09, 2034 | Amgen Inc. |
| Prolia And Xgeva | USUS11130980 | Use of monensin to regulate glycosylation of recombinant proteins | Apr 05, 2035 | Amgen Inc. |
| Prolia And Xgeva | USUS10421987 | Methods for increasing mannose content of recombinant proteins | May 29, 2034 | Amgen Inc. |
| Prolia And Xgeva | USUS9012178 | Dipeptides to enhance yield and viability from cell cultures | Aug 05, 2031 | Amgen Inc. |
| Prolia And Xgeva | USUS11098079 | Charged depth filtration of antigen-binding proteins | Jul 21, 2037 | Amgen Inc. |
| Prolia And Xgeva | USUS7888101 | Host cells comprising alpha 1,2 mannosidase and culture methods thereof | Apr 06, 2027 | Amgen Inc. |
| Prolia And Xgeva | USUS8460896 | Host cells and culture methods | Dec 06, 2026 | Amgen Inc. |
| Prolia And Xgeva | USUS9359435 | Methods for modulating mannose content of recombinant proteins | May 22, 2027 | Amgen Inc. |
| Prolia And Xgeva | USUS8053236 | Feed media | Jan 19, 2030 | Amgen Inc. |
| Prolia And Xgeva | USUS10583397 | Process control systems and methods for use with filters and filtration processes | Jul 28, 2035 | Amgen Inc. |
| Prolia And Xgeva | USUS11384378 | Methods for harvesting mammalian cell cultures | Jun 04, 2035 | Amgen Inc. |
| Prolia And Xgeva | USUS10907186 | Overexpression of n-glycosylation pathway regulators to modulate glycosylation of recombinant proteins | Dec 11, 2034 | Amgen Inc. |
| Prolia And Xgeva | USUS10227627 | Overexpression of N-glycosylation pathway regulators to modulate glycosylation of recombinant proteins | Dec 11, 2034 | Amgen Inc. |
| Prolia And Xgeva | USUS9133493 | Method for culturing mammalian cells to improve recombinant protein production | Apr 20, 2032 | Amgen Inc. |
| Prolia And Xgeva | USUS10167492 | Process for manipulating the level of glycan content of a glycoprotein | Dec 01, 2035 | Amgen Inc. |
| Prolia And Xgeva | USUS9328134 | Carbohydrate phosphonate derivatives as modulators of glycosylation | Feb 20, 2034 | Amgen Inc. |
| Prolia And Xgeva | USUS11275090 | Quantitation of glycan moiety in recombinant glycoproteins | Jul 02, 2037 | Amgen Inc. |
| Prolia And Xgeva | USUS11486883 | Method for using light scattering in real time to directly monitor and control impurity removal in purification processes | Mar 26, 2033 | Amgen Inc. |
| Prolia And Xgeva | USUS7662930 | Polishing steps used in multi-step protein purification processes | Apr 24, 2027 | Amgen Inc. |
| Prolia And Xgeva | USUS11685772 | Mammalian cell culture | Jun 29, 2032 | Amgen Inc. |
| Prolia And Xgeva | USUS7427659 | Process for purifying proteins in a hydrophobic interaction chromatography flow-through fraction | Mar 15, 2025 | Amgen Inc. |
| Prolia And Xgeva | USUS11299760 | Use of monensin to regulate glycosylation of recombinant proteins | Oct 30, 2034 | Amgen Inc. |
| Prolia And Xgeva | USUS11077404 | Process control systems and methods for use with filters and filtration processes | May 13, 2035 | Amgen Inc. |
| Prolia And Xgeva | USUS8680248 | Host cells comprising alpha 1,2 mannosidase and culture methods thereof | Dec 06, 2026 | Amgen Inc. |
| Prolia And Xgeva | USUS11427848 | Methods for harvesting mammalian cell cultures | Jun 04, 2035 | Amgen Inc. |
| Prolia And Xgeva | USUS9388447 | Method for culturing mammalian cells to improve recombinant protein production | Apr 20, 2032 | Amgen Inc. |
| Prolia And Xgeva | USUS11459595 | Methods for increasing mannose content of recombinant proteins | Mar 10, 2034 | Amgen Inc. |
| Prolia And Xgeva | USUS11292829 | Mammalian cell culture | Jun 29, 2032 | Amgen Inc. |
| Prolia And Xgeva | USUS11434514 | Methods for increasing mannose content of recombinant proteins | May 29, 2034 | Amgen Inc. |
| Prolia And Xgeva | USUS8247210 | Host cells comprising alpha 1,2 mannosidase and culture methods thereof | Dec 06, 2026 | Amgen Inc. |
| Prolia And Xgeva | USUS9481901 | Methods for increasing mannose content of recombinant proteins | May 29, 2034 | Amgen Inc. |
| Prolia And Xgeva | USUS11744950 | Controlled dispense syringe | Nov 21, 2039 | Amgen Inc. |
| Prolia And Xgeva | USUS11946085 | Methods for increasing mannose content of recombinant proteins | May 29, 2034 | Amgen Inc. |
| Prolia And Xgeva | USUS8058418 | Polynucleotides encoding heavy and light chains of antibodies to OPGL |
Nov 30, 2023
(Expired) | Amgen Inc. |
| Prolia And Xgeva | USUS11634476 | Mammalian cell culture | Jun 29, 2032 | Amgen Inc. |
| Prolia And Xgeva | USUS11952605 | Methods for increasing mannose content of recombinant proteins | Mar 10, 2034 | Amgen Inc. |
| Prolia And Xgeva | USUS10894972 | Methods for increasing mannose content of recombinant proteins | May 29, 2034 | Amgen Inc. |
| Prolia And Xgeva | USUS10822630 | Process for manipulating the level of glycan content of a glycoprotein | Dec 01, 2035 | Amgen Inc. |
| Prolia And Xgeva | USUS7928205 | Methods for refolding of recombinant antibodies | Feb 12, 2027 | Amgen Inc. |
| Prolia And Xgeva | USUS9320816 | Methods of treating cell culture media for use in a bioreactor | Nov 14, 2030 | Amgen Inc. |
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