Cyclophosphamide Patent Expiration

Cyclophosphamide was first introduced by Baxter Healthcare Corp in its drug Cytoxan on Approved Prior to Jan 1, 1982. Other drugs containing Cyclophosphamide are Cytoxan (Lyophilized), Cyclophosphamide, Lyophilized Cytoxan. 24 different companies have introduced drugs containing Cyclophosphamide.


Cyclophosphamide Patents

Given below is the list of patents protecting Cyclophosphamide, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Cyclophosphamide US10993952 Stable ready to use cyclophosphamide liquid formulations Feb 15, 2036 Dr Reddys
Cyclophosphamide US11382923 Stable liquid formulations of cyclophosphamide and processes to prepare the same Dec 01, 2035 Avyxa Holdings
Cyclophosphamide US10849916 Stable liquid formulations of cyclophosphamide and its impurities Jul 13, 2035 Avyxa Holdings
Cyclophosphamide US9662342 Formulations of cyclophosphamide liquid concentrate Jun 26, 2035 Eugia Pharma Speclts



A patent's expiry date may change depending upon legal activities going on that patent. Critical activities like abandoning of a patent, term extension of a patent or amendment of its claims can increase or decrease the life of a patent hence affecting its expiry date and in turn affecting the generic launch date of that drug. Tracking these ongoing activities on a patent application helps to keep an eye on the latest developments in the patent process of the drug which can give an idea of how early a drug's generic could be available. The next section provides a list of recent legal activities on Cyclophosphamide's patents.

Given below is the list recent legal activities going on the following patents of Cyclophosphamide.

Activity Date Patent Number
Patent litigations
Payment of Maintenance Fee, 4th Year, Large Entity 30 May, 2024 US10849916
Payment of Maintenance Fee, 4th Yr, Small Entity 08 May, 2024 US10993952(Litigated)
Patent Issue Date Used in PTA Calculation 12 Jul, 2022 US11382923
Recordation of Patent Grant Mailed 12 Jul, 2022 US11382923
Email Notification 23 Jun, 2022 US11382923
Issue Notification Mailed 22 Jun, 2022 US11382923
Application Is Considered Ready for Issue 08 Jun, 2022 US11382923
Dispatch to FDC 08 Jun, 2022 US11382923
Issue Fee Payment Received 06 Jun, 2022 US11382923
Issue Fee Payment Verified 06 Jun, 2022 US11382923


Cyclophosphamide's Family Patents

Family Patents

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Cyclophosphamide Generic API Manufacturers

Several generic applications have been filed for Cyclophosphamide. The first generic version for Cyclophosphamide was by Bedford Laboratories Div Ben Venue Laboratories Inc and was approved on Feb 16, 1982. And the latest generic version is by Hainan Poly Pharm Co Ltd and was approved on Dec 26, 2024.

Given below is the list of companies who have filed for Cyclophosphamide generic, along with the locations of their manufacturing plants worldwide.