Cyclophosphamide Patent Expiration

Cyclophosphamide was first introduced by Baxter Healthcare Corp in its drug Cytoxan on Approved Prior to Jan 1, 1982. Other drugs containing Cyclophosphamide are Cytoxan (Lyophilized), Frindovyx, Lyophilized Cytoxan, Cyclophosphamide. 24 different companies have introduced drugs containing Cyclophosphamide.


Cyclophosphamide Patents

Given below is the list of patents protecting Cyclophosphamide, along with the drug name that holds that patent and the company name owning that drug.

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Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Cyclophosphamide US10993952 Stable ready to use cyclophosphamide liquid formulations Feb 15, 2036 Dr Reddys
Cyclophosphamide US12329767 Stable Ready To Use Cyclophosphamide Liquid Formulations Feb 15, 2036 Dr Reddys
Frindovyx US11382923 Stable liquid formulations of cyclophosphamide and processes to prepare the same Dec 01, 2035 Avyxa Holdings
Frindovyx US10849916 Stable liquid formulations of cyclophosphamide and its impurities Jul 13, 2035 Avyxa Holdings
Cyclophosphamide US9662342 Formulations of cyclophosphamide liquid concentrate Jun 26, 2035 Eugia Pharma Speclts



A patent's expiry date may change depending upon legal activities going on that patent. Critical activities like abandoning of a patent, term extension of a patent or amendment of its claims can increase or decrease the life of a patent hence affecting its expiry date and in turn affecting the generic launch date of that drug. Tracking these ongoing activities on a patent application helps to keep an eye on the latest developments in the patent process of the drug which can give an idea of how early a drug's generic could be available. The next section provides a list of recent legal activities on Cyclophosphamide's patents.

Given below is the list recent legal activities going on the following patents of Cyclophosphamide.

Activity Date Patent Number
Patent litigations
Recordation of Patent Grant Mailed 24 Jun, 2025 US12329767
Patent eGrant Notification 17 Jun, 2025 US12329767
Email Notification 17 Jun, 2025 US12329767
Recordation of Patent eGrant 17 Jun, 2025 US12329767
Patent Issue Date Used in PTA Calculation 17 Jun, 2025 US12329767
Mail Patent eGrant Notification 17 Jun, 2025 US12329767
Email Notification 05 Jun, 2025 US12329767
Issue Notification Mailed 04 Jun, 2025 US12329767
Application Is Considered Ready for Issue 16 May, 2025 US12329767
Dispatch to FDC 16 May, 2025 US12329767


Cyclophosphamide's Family Patents

Family Patents

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Cyclophosphamide Generic API Manufacturers

Several generic applications have been filed for Cyclophosphamide. The first generic version for Cyclophosphamide was by Bedford Laboratories Div Ben Venue Laboratories Inc and was approved on Feb 16, 1982. And the latest generic version is by Hainan Poly Pharm Co Ltd and was approved on Dec 26, 2024.

Given below is the list of companies who have filed for Cyclophosphamide generic, along with the locations of their manufacturing plants worldwide.