Crizotinib Patent Expiration

Crizotinib is used for treating ALK-positive inflammatory myofibroblastic tumors, metastatic non-small cell lung cancer, and relapsed or refractory systemic anaplastic large cell lymphoma in pediatric and young adult patients over 1 year of age. It was first introduced by Pf Prism Cv in its drug Xalkori on Aug 26, 2011.


Crizotinib Patents

Given below is the list of patents protecting Crizotinib, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Xalkori US8217057 Polymorphs of a c-MET/HGFR inhibitor Nov 06, 2029 Pf Prism Cv
Xalkori US7858643 Enantiomerically pure aminoheteroaryl compounds as protein kinase inhibitors Oct 08, 2029 Pf Prism Cv
Xalkori US7825137 Method of treating abnormal cell growth May 12, 2027 Pf Prism Cv
Xalkori US7230098 Aminoheteroaryl compounds as protein kinase inhibitors Aug 26, 2025 Pf Prism Cv
Xalkori US8785632 Enantiomerically pure aminoheteroaryl compounds as protein kinase inhibitors Mar 01, 2025 Pf Prism Cv



A patent's expiry date may change depending upon legal activities going on that patent. Critical activities like abandoning of a patent, term extension of a patent or amendment of its claims can increase or decrease the life of a patent hence affecting its expiry date and in turn affecting the generic launch date of that drug. Tracking these ongoing activities on a patent application helps to keep an eye on the latest developments in the patent process of the drug which can give an idea of how early a drug's generic could be available. The next section provides a list of recent legal activities on Crizotinib's patents.

Given below is the list recent legal activities going on the following patents of Crizotinib.

Activity Date Patent Number
Patent litigations
Payment of Maintenance Fee, 12th Year, Large Entity 14 Dec, 2023 US8217057
Payment of Maintenance Fee, 12th Year, Large Entity 11 May, 2022 US7858643
Payment of Maintenance Fee, 12th Year, Large Entity 12 Apr, 2022 US7825137
Payment of Maintenance Fee, 8th Year, Large Entity 09 Dec, 2021 US8785632
Payment of Maintenance Fee, 8th Year, Large Entity 18 Dec, 2019 US8217057
Payment of Maintenance Fee, 12th Year, Large Entity 15 Nov, 2018 US7230098
Payment of Maintenance Fee, 8th Year, Large Entity 09 May, 2018 US7858643
Payment of Maintenance Fee, 8th Year, Large Entity 13 Apr, 2018 US7825137
Payment of Maintenance Fee, 4th Year, Large Entity 15 Dec, 2017 US8785632
Email Notification 28 Apr, 2016 US7230098


Crizotinib's Family Patents

Family Patents

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