Carbidopa; Levodopa Patent Expiration

Carbidopa; Levodopa is Used for treating Parkinson's disease and related conditions such as post-encephalitic parkinsonism and parkinsonism from carbon monoxide or manganese intoxication. It was first introduced by Organon Llc A Sub Of Organon And Co in its drug Sinemet on Approved Prior to Jan 1, 1982. Other drugs containing Carbidopa; Levodopa are Rytary, Sinemet Cr, Crexont, Duopa, Dhivy. 29 different companies have introduced drugs containing Carbidopa; Levodopa.


Carbidopa; Levodopa Patents

Given below is the list of patents protecting Carbidopa; Levodopa, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Crexont US11986449 Levodopa dosing regimen Dec 21, 2041 Impax
Crexont US12109185 Levodopa dosing regimen Dec 21, 2041 Impax
Crexont US12194150 Levodopa dosing regimen Dec 21, 2041 Impax
Crexont US12201596 Levodopa dosing regimen Dec 21, 2041 Impax
Crexont US12263148 Levodopa dosing regimen Dec 21, 2041 Impax
Crexont US12263149 Levodopa dosing regimen Dec 21, 2041 Impax
Crexont US12295931 Levodopa dosing regimen Dec 21, 2041 Impax
Crexont US12303481 Levodopa dosing regimen Dec 21, 2041 Impax
Crexont US12303482 Levodopa dosing regimen Dec 21, 2041 Impax
Dhivy US11033521 Levodopa fractionated dose composition and use Mar 28, 2039 Avion Pharms
Dhivy US11439613 Levodopa fractionated dose composition and use Mar 28, 2039 Avion Pharms
Dhivy US11819485 Levodopa fractionated dose composition and use Mar 28, 2039 Avion Pharms
Crexont US10098845 Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof Oct 07, 2034 Impax
Crexont US10292935 Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof Oct 07, 2034 Impax
Crexont US10688058 Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof Oct 07, 2034 Impax
Crexont US10973769 Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof Oct 07, 2034 Impax
Crexont US10987313 Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof Oct 07, 2034 Impax
Crexont US11357733 Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof Oct 07, 2034 Impax
Crexont US11622941 Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof Oct 07, 2034 Impax
Crexont US11666538 Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof Oct 07, 2034 Impax
Crexont US12064521 Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof Oct 07, 2034 Impax
Crexont US12128141 Muco-adhesive, controlled release formulation of levodopa and/or esters of levodopa and uses thereof Oct 07, 2034 Impax
Crexont US12178918 Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof Oct 07, 2034 Impax
Crexont US12178919 Muco-adhesive, controlled release formulation of levodopa and/or esters of levodopa and uses thereof Oct 07, 2034 Impax
Crexont US12274793 Muco-adhesive, controlled release formulation of levodopa and/or esters of levodopa and uses thereof Oct 07, 2034 Impax
Crexont US12303605 Muco-adhesive, controlled release formulation of levodopa and/or esters of levodopa and uses thereof Oct 07, 2034 Impax
Rytary US8377474 Controlled release formulations of levodopa and uses thereof Dec 26, 2028 Impax
Rytary US8454998 Controlled release formulations of levodopa and uses thereof Dec 26, 2028 Impax
Rytary US8557283 Controlled release formulations of levodopa and uses thereof Dec 26, 2028 Impax
Rytary US9089607 Controlled release formulations of levodopa and uses thereof Dec 26, 2028 Impax
Rytary US9089608 Controlled release formulations of levodopa and uses thereof Dec 26, 2028 Impax
Rytary US9463246 Controlled release formulations of levodopa and uses thereof Dec 26, 2028 Impax
Rytary US9533046 Controlled release formulations of levodopa and uses thereof Dec 26, 2028 Impax
Rytary US9901640 Controlled release formulations of levodopa and uses thereof Dec 26, 2028 Impax
Rytary US7094427 Combination immediate release controlled release levodopa/carbidopa dosage forms May 29, 2022

(Expired)

Impax



A patent's expiry date may change depending upon legal activities going on that patent. Critical activities like abandoning of a patent, term extension of a patent or amendment of its claims can increase or decrease the life of a patent hence affecting its expiry date and in turn affecting the generic launch date of that drug. Tracking these ongoing activities on a patent application helps to keep an eye on the latest developments in the patent process of the drug which can give an idea of how early a drug's generic could be available. The next section provides a list of recent legal activities on Carbidopa; Levodopa's patents.

Given below is the list recent legal activities going on the following patents of Carbidopa; Levodopa.

Activity Date Patent Number
Patent litigations
Payment of Maintenance Fee, 8th Year, Large Entity 03 Jul, 2024 US9533046
Payment of Maintenance Fee, 8th Year, Large Entity 11 Apr, 2024 US9463246(Litigated)
Email Notification 24 May, 2023 US8377474(Litigated)
Change in Power of Attorney (May Include Associate POA) 24 May, 2023 US8377474(Litigated)
Payment of Maintenance Fee, 8th Year, Large Entity 30 Jan, 2023 US9089607(Litigated)
Payment of Maintenance Fee, 8th Year, Large Entity 30 Jan, 2023 US9089608(Litigated)
Payment of Maintenance Fee, 4th Year, Large Entity 11 Aug, 2021 US9901640
Payment of Maintenance Fee, 8th Year, Large Entity 31 Mar, 2021 US8557283(Litigated)
Payment of Maintenance Fee, 8th Year, Large Entity 25 Sep, 2020 US8454998(Litigated)
Payment of Maintenance Fee, 8th Year, Large Entity 06 Aug, 2020 US8377474(Litigated)


Carbidopa; Levodopa's Family Patents

Family Patents

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Carbidopa; Levodopa Generic API Manufacturers

Several generic applications have been filed for Carbidopa; Levodopa. The first generic version for Carbidopa; Levodopa was by Dr Reddys Laboratories Sa and was approved on Aug 28, 1992. And the latest generic version is by Ascent Pharmaceuticals Inc and was approved on Jan 14, 2025.

Given below is the list of companies who have filed for Carbidopa; Levodopa generic, along with the locations of their manufacturing plants worldwide.