Cabozantinib S-malate Patent Expiration

Cabozantinib S-Malate is used for treating advanced renal cell carcinoma, differentiated thyroid cancer, and hepatocellular carcinoma. It was first introduced by Exelixis Inc in its drug Cometriq on Nov 29, 2012. Another drug containing Cabozantinib S-Malate is Cabometyx. 2 different companies have introduced drugs containing Cabozantinib S-Malate.


Cabozantinib S-malate Patents

Given below is the list of patents protecting Cabozantinib S-malate, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Cabometyx US10034873 C-met modulator pharmaceutical compositions Jul 18, 2031 Exelixis Inc
Cabometyx US10039757 C-Met modulator pharmaceutical compositions Jul 18, 2031 Exelixis Inc
Cabometyx US11091439 Malate salt of N-(4-{[6,7-bis(methyloxy) quinolin-4-yl]oxy}phenyl)-N′-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide, and crystalline forms therof for the treatment of cancer Jan 15, 2030 Exelixis Inc
Cabometyx US11091440 Malate salt of N-(4-{[6,7-bis(methyloxy) quinolin-4-yl]oxy}phenyl)- N′-(4-fluorophenyl)cyclopropane-1,1 -dicarboxamide, and crystalline forms thereof for the treatment of cancer Jan 15, 2030 Exelixis Inc
Cabometyx US11098015 Malate salt of N-(4-{[6,7-bis(methyloxy) quinolin-4-yl]oxy}phenyl)-N′-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide, and crystalline forms thereof for the treatment of cancer Jan 15, 2030 Exelixis Inc
Cabometyx US11141413 Method of treating renal cell carcinoma using N-(4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)-N′-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide, (2S)-hydroxybutanedioate Apr 17, 2037 Exelixis Inc
Cabometyx US11298349 Processes for preparing quinoline compounds and pharmaceutical compositions containing such compounds Feb 10, 2032 Exelixis Inc
Cabometyx US7579473 c-Met modulators and methods of use Aug 14, 2026 Exelixis Inc
Cabometyx US8497284 C-met modulators and method of use Sep 24, 2024 Exelixis Inc
Cabometyx US8877776 (L)-malate salt of N-(4-{[6,7-bis(methyloxy) quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide Oct 08, 2030 Exelixis Inc
Cabometyx US9724342 C-met modulator pharmaceutical compositions Jul 09, 2033 Exelixis Inc
Cometriq US11091439 Malate salt of N-(4-{[6,7-bis(methyloxy) quinolin-4-yl]oxy}phenyl)-N′-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide, and crystalline forms therof for the treatment of cancer Jan 15, 2030 Exelixis
Cometriq US11091440 Malate salt of N-(4-{[6,7-bis(methyloxy) quinolin-4-yl]oxy}phenyl)- N′-(4-fluorophenyl)cyclopropane-1,1 -dicarboxamide, and crystalline forms thereof for the treatment of cancer Jan 15, 2030 Exelixis
Cometriq US11098015 Malate salt of N-(4-{[6,7-bis(methyloxy) quinolin-4-yl]oxy}phenyl)-N′-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide, and crystalline forms thereof for the treatment of cancer Jan 15, 2030 Exelixis
Cometriq US11298349 Processes for preparing quinoline compounds and pharmaceutical compositions containing such compounds Feb 10, 2032 Exelixis
Cometriq US7579473 c-Met modulators and methods of use Aug 14, 2026 Exelixis
Cometriq US8877776 (L)-malate salt of N-(4-{[6,7-bis(methyloxy) quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide Oct 08, 2030 Exelixis
Cometriq US9717720 Processes for preparing quinoline compounds and pharmaceutical compositions containing such compounds Feb 10, 2032 Exelixis