Brimonidine Tartrate Patent Expiration

Brimonidine Tartrate was first introduced by Allergan Inc in its drug Alphagan on Sep 6, 1996. Other drugs containing Brimonidine Tartrate are Qoliana, Alphagan P, Lumify, Lumify Preservative Free, Mirvaso. 17 different companies have introduced drugs containing Brimonidine Tartrate.


Brimonidine Tartrate Patents

Given below is the list of patents protecting Brimonidine Tartrate, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Mirvaso US10201517 Brimonidine gel compositions and methods of use Jun 13, 2031 Galderma Labs Lp
Mirvaso US8053427 Brimonidine gel composition Jun 13, 2031 Galderma Labs Lp
Mirvaso US8163725 Gel compositions and methods of use Jun 13, 2031 Galderma Labs Lp
Mirvaso US8513247 Methods and compositions for safe and effective treatment of erythema Mar 25, 2031 Galderma Labs Lp
Mirvaso US8513249 Methods and compositions for safe and effective treatment of erythema Mar 25, 2031 Galderma Labs Lp
Mirvaso US9861631 Methods and compositions for safe and effective treatment of erythema Mar 25, 2031 Galderma Labs Lp
Mirvaso US9861632 Methods and compositions for safe and effective treatment of erythema Mar 25, 2031 Galderma Labs Lp
Lumify US8293742 Preferential vasoconstriction compositions and methods of use Jul 14, 2030 Bausch And Lomb Inc
Lumify US9259425 Compositions and methods for eye whitening Jul 14, 2030 Bausch And Lomb Inc
Lumify Preservative Free US8293742 Preferential vasoconstriction compositions and methods of use Jul 14, 2030 Bausch And Lomb Inc
Lumify Preservative Free US9259425 Compositions and methods for eye whitening Jul 14, 2030 Bausch And Lomb Inc
Lumify US11596600 Vasoconstriction compositions and methods of use Jul 27, 2029 Bausch And Lomb Inc
Lumify US11833245 Vasoconstriction compositions and methods of use Jul 27, 2029 Bausch And Lomb Inc
Lumify Preservative Free US11596600 Vasoconstriction compositions and methods of use Jul 27, 2029 Bausch And Lomb Inc
Mirvaso US7439241 Compounds, formulations, and methods for treating or preventing rosacea Aug 25, 2025 Galderma Labs Lp
Qoliana US7265117 Topical brimonidine tartrate formulations that lack chlorine dioxide Aug 19, 2025 Sandoz
Mirvaso US8231885 Compounds, formulations, and methods for ameliorating telangiectasis May 24, 2025

(Expired)

Galderma Labs Lp
Mirvaso US8410102 Methods and compositions for treating or preventing erythema May 24, 2025

(Expired)

Galderma Labs Lp
Mirvaso US8426410 Compounds, formulations, and methods for treating or preventing inflammatory skin disorders May 24, 2025

(Expired)

Galderma Labs Lp
Mirvaso US8859551 Compounds, formulations, and methods for treating or preventing inflammatory skin disorders May 25, 2024

(Expired)

Galderma Labs Lp
Alphagan P US8858961

(Pediatric)

Compositions containing alpha-2-adrenergic agonist components Mar 02, 2024

(Expired)

Abbvie
Alphagan P US8858961 Compositions containing alpha-2-adrenergic agonist components Sep 02, 2023

(Expired)

Abbvie
Alphagan P US6641834

(Pediatric)

Compositions containing alpha-2-adrenergic agonist components Jan 28, 2022

(Expired)

Abbvie
Alphagan P US6673337

(Pediatric)

Compositions containing alpha-2-adrenergic agonist components Jan 26, 2022

(Expired)

Abbvie
Alphagan P US6627210

(Pediatric)

Compositions containing α-2-adrenergic agonist components Jan 18, 2022

(Expired)

Abbvie
Alphagan P US6562873

(Pediatric)

Compositions containing therapeutically active components having enhanced solubility Jan 10, 2022

(Expired)

Abbvie
Alphagan P US9295641

(Pediatric)

Compositions containing alpha-2-adrenergic agonist components Jan 10, 2022

(Expired)

Abbvie
Alphagan P US9687443

(Pediatric)

Compositions containing alpha-2-adrenergic agonist components Jan 10, 2022

(Expired)

Abbvie
Alphagan P US6641834 Compositions containing alpha-2-adrenergic agonist components Jul 28, 2021

(Expired)

Abbvie
Alphagan P US6673337 Compositions containing alpha-2-adrenergic agonist components Jul 26, 2021

(Expired)

Abbvie
Alphagan P US6627210 Compositions containing α-2-adrenergic agonist components Jul 18, 2021

(Expired)

Abbvie
Alphagan P US10307368 Compositions containing alpha-2-adrenergic agonist components Jul 10, 2021

(Expired)

Abbvie
Alphagan P US6562873 Compositions containing therapeutically active components having enhanced solubility Jul 10, 2021

(Expired)

Abbvie
Alphagan P US9295641 Compositions containing alpha-2-adrenergic agonist components Jul 10, 2021

(Expired)

Abbvie
Alphagan P US9687443 Compositions containing alpha-2-adrenergic agonist components Jul 10, 2021

(Expired)

Abbvie
Alphagan P US5424078

(Pediatric)

Aqueous ophthalmic formulations and methods for preserving same Dec 13, 2012

(Expired)

Abbvie



A patent's expiry date may change depending upon legal activities going on that patent. Critical activities like abandoning of a patent, term extension of a patent or amendment of its claims can increase or decrease the life of a patent hence affecting its expiry date and in turn affecting the generic launch date of that drug. Tracking these ongoing activities on a patent application helps to keep an eye on the latest developments in the patent process of the drug which can give an idea of how early a drug's generic could be available. The next section provides a list of recent legal activities on Brimonidine Tartrate's patents.

Given below is the list recent legal activities going on the following patents of Brimonidine Tartrate.

Activity Date Patent Number
Patent litigations
Payment of Maintenance Fee, 12th Year, Large Entity 22 Feb, 2019 US7265117
Patent Issue Date Used in PTA Calculation 04 Sep, 2007 US7265117
Recordation of Patent Grant Mailed 04 Sep, 2007 US7265117
Issue Notification Mailed 15 Aug, 2007 US7265117
Dispatch to FDC 31 Jul, 2007 US7265117
Application Is Considered Ready for Issue 13 Jul, 2007 US7265117
Issue Fee Payment Received 09 Jul, 2007 US7265117
Issue Fee Payment Verified 09 Jul, 2007 US7265117
Mail Notice of Allowance 27 Jun, 2007 US7265117
Notice of Allowance Data Verification Completed 23 Jun, 2007 US7265117


Brimonidine Tartrate's Family Patents

Family Patents

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Brimonidine Tartrate Generic API Manufacturers

Several generic applications have been filed for Brimonidine Tartrate. The first generic version for Brimonidine Tartrate was by Bausch And Lomb Pharmaceuticals Inc and was approved on May 28, 2003. And the latest generic version is by Upsher Smith Laboratories Llc and was approved on Jul 30, 2025.

Given below is the list of companies who have filed for Brimonidine Tartrate generic, along with the locations of their manufacturing plants worldwide.