Brimonidine Tartrate; Timolol Maleate Patent Expiration

Brimonidine Tartrate; Timolol Maleate is used for lowering elevated intraocular pressure in patients with glaucoma or ocular hypertension. It was first introduced by Abbvie Inc in its drug Combigan on Oct 30, 2007. 11 different companies have introduced drugs containing Brimonidine Tartrate; Timolol Maleate.


Brimonidine Tartrate; Timolol Maleate Patents

Given below is the list of patents protecting Brimonidine Tartrate; Timolol Maleate, along with the drug name that holds that patent and the company name owning that drug.

Filter patents by

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Combigan US7323463 Combination of brimonidine and timolol for topical ophthalmic use Jan 19, 2023

(Expired)

Abbvie
Combigan US7030149 Combination of brimonidine timolol for topical ophthalmic use Apr 19, 2022

(Expired)

Abbvie
Combigan US7320976 Combination of brimonidine and timolol for topical ophthalmic use Apr 19, 2022

(Expired)

Abbvie
Combigan US7642258 Combination of brimonidine and timolol for topical ophthalmic use Apr 19, 2022

(Expired)

Abbvie
Combigan US8133890 Combination of brimonidine and timolol for topical ophthalmic use Apr 19, 2022

(Expired)

Abbvie
Combigan US8354409 Combination of brimonidine and timolol for topical ophthalmic use Apr 19, 2022

(Expired)

Abbvie
Combigan US8748425 Combination of brimonidine and timolol for topical ophthalmic use Apr 19, 2022

(Expired)

Abbvie
Combigan US9474751 Combination of brimonidine and timolol for topical ophthalmic use Apr 19, 2022

(Expired)

Abbvie
Combigan US9770453 Combination of brimonidine and timolol for topical ophthalmic use Apr 19, 2022

(Expired)

Abbvie
Combigan US9907801 Combination of brimonidine and timolol for topical ophthalmic use Apr 19, 2022

(Expired)

Abbvie
Combigan US9907802 Combination of brimonidine and timolol for topical ophthalmic use Apr 19, 2022

(Expired)

Abbvie



Brimonidine Tartrate; Timolol Maleate's Family Patents

Family Patents

Explore Our Curated Drug Screens

Drugs Generating Over $1 Billion in Annual Revenue
Explore the top-performing drugs that dominate the pharmaceutical industry
View List
NCE-1 Patent Expiry in the Next 1 Year
Identify opportunities as new chemical entity (NCE-1) patents approach expiry
View List
Recently Granted Patents in EP
Find the opportunity to file Oppositions
View List

Brimonidine Tartrate; Timolol Maleate Generic API Manufacturers

Several generic applications have been filed for Brimonidine Tartrate; Timolol Maleate. The first generic version for Brimonidine Tartrate; Timolol Maleate was by Sandoz Inc and was approved on Apr 4, 2022. And the latest generic version is by Caplin Steriles Ltd and was approved on Feb 25, 2025.

Given below is the list of companies who have filed for Brimonidine Tartrate; Timolol Maleate generic, along with the locations of their manufacturing plants worldwide.