Brensocatib Patent Expiration

Brensocatib was first introduced by Insmed Inc in its drug Brinsupri on Aug 12, 2025.


Brensocatib Patents

Given below is the list of patents protecting Brensocatib, along with the drug name that holds that patent and the company name owning that drug.

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Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Brinsupri US12059424 Pharmaceutical Compositions Comprising (2S)-N-{(1S)-1-Cyano-2-[4-(3-Methyl-2-Oxo-2,3-Dihydro-1,3-Benzoxazol-5-Yl)Phenyl]Ethyl}-1,4-Oxazepane-2-Carboxamide Feb 21, 2040 Insmed Inc
Brinsupri US12201638 Pharmaceutical Compositions Comprising (2S)-N-{(1S)-1-Cyano-2-[4-(3-Methyl-2-Oxo-2,3-Dihydro-1,3-Benzoxazol-5-Yl)Phenyl]Ethyl}-1,4-Oxazepane-2-Carboxamide Mar 01, 2039 Insmed Inc
Brinsupri US9522894 Certain (2S)-N-[(1S)-1-Cyano-2-Phenylethyl]-1,4-Oxazepane-2-Carboxamides As Dipeptidyl Peptidase 1 Inhibitors Mar 12, 2035 Insmed Inc
Brinsupri US10287258 Certain (2S)-N-[(1S)-1-Cyano-2-Phenylethyl]-1,4-Oxazepane-2-Carboxamides As Dipeptidyl Peptidase 1 Inhibitors Jan 21, 2035 Insmed Inc
Brinsupri US10669245 Certain (2S)-N-[(1S)-1-Cyano-2-Phenylethyl]-1,4-Oxazepane-2-Carboxamides Dipeptidyl Peptidase 1 Inhibitors Jan 21, 2035 Insmed Inc
Brinsupri US11655221 Certain (2S)-N-[(1S)-1-Cyano-2-Phenylethyl]-1,4-Oxazepane-2-Carboxamides As Dipeptidyl Peptidase 1 Inhibitors Jan 21, 2035 Insmed Inc
Brinsupri US11655222 Certain (2S)-N-[(1S)-1-Cyano-2-Phenylethyl]-1,4-Oxazepane-2-Carboxamides As Dipeptidyl Peptidase 1 Inhibitors Jan 21, 2035 Insmed Inc
Brinsupri US11655223 Certain (2S)-N-[(1 S)-1-Cyano-2-Phenylethyl]-1,4-Oxazepane-2-Carboxamides As Dipeptidyl Peptidase 1 Inhibitors Jan 21, 2035 Insmed Inc
Brinsupri US11655224 Certain (2S)-N-[(1S)-1-Cyano-2-Phenylethyl]-1,4-Oxazepane-2-Carboxamides As Dipeptidyl Peptidase 1 Inhibitors Jan 21, 2035 Insmed Inc
Brinsupri US11673871 Certain (2S)-N-[(1S)-1-Cyano-2-Phenylethyl]-1,4-Oxazepane-2-Carboxamides As Dipeptidyl Peptidase 1 Inhibitors Jan 21, 2035 Insmed Inc
Brinsupri US11773069 Certain (2S)-N-[(1S)-1-Cyano-2-Phenylethyl]-1,4-Oxazepane-2-Carboxamides As Dipeptidyl Peptidase 1 Inhibitors Jan 21, 2035 Insmed Inc
Brinsupri US11814359 Certain (2S)-N-[(1S)-1-Cyano-2-Phenylethyl]-1,4-Oxazepane-2-Carboxamides As Dipeptidyl Peptidase 1 Inhibitors Jan 21, 2035 Insmed Inc
Brinsupri US12054465 Certain (2S)-N-[(1S)-1-Cyano-2-Phenylethyl]-1,4-Oxazepane-2-Carboxamides As Dipeptidyl Peptidase 1 Inhibitors Jan 21, 2035 Insmed Inc
Brinsupri US9815805 Certain (25)-N-[(1S)-1-Cyano-2-Phenylethyl]-1,4-Oxazepane-2-Carboxamides As Dipeptidyl Peptidase 1 Inhibitors Jan 21, 2035 Insmed Inc



Brensocatib's Family Patents

Family Patents

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Clinical Trials

Recent Clinical Trials on Brensocatib:

Sometimes companies keep conducting clinical trials even after the drug's approval to discover new formulations, methods of use, or new treatment indications, so they could file for additional patents or receive regulatory exclusivity extensions, such as pediatric exclusivity, potentially delaying generic competition. Based on these recent clinical trials, generic companies need to consider the potential for new intellectual property or regulatory hurdles. These strategic moves by the drug owner might delay generic substitution or lead to additional sales of the brand drug, even after patent expiry.

Title Lead Sponsor Collaborators Status Phases
Clinical Trials
A Study of the Efficacy and Safety of Brensocatib in Adults With Moderate to Severe Hidradenitis Suppurativa (HS) Insmed Incorporated NA ACTIVE NOT RECRUITING
(Mar 1, 2026)
PHASE2


Brensocatib Generic API Manufacturers

Given below is the list of companies who have filed for Brensocatib generic, along with the locations of their manufacturing plants worldwide.