Apremilast Patent Expiration
Apremilast is used for treating psoriatic arthritis and plaque psoriasis with dosage titration and inhibiting PDE4. It was first introduced by Amgen Inc
Apremilast Patents
Given below is the list of patents protecting Apremilast, along with the drug name that holds that patent and the company name owning that drug.
Drug Used in | Drug Patent Number | Drug Patent Title | Drug Patent Expiry | Drug Owner |
---|---|---|---|---|
Otezla |
US10092541 (Pediatric) | Methods for the treatment of diseases ameliorated by PDE4 inhibition using dosage titration of apremilast | Nov 29, 2034 | Amgen Inc |
Otezla |
US9872854 (Pediatric) | Methods for the treatment of psoriatic arthritis using apremilast | Nov 29, 2034 | Amgen Inc |
Otezla | US10092541 | Methods for the treatment of diseases ameliorated by PDE4 inhibition using dosage titration of apremilast | May 29, 2034 | Amgen Inc |
Otezla | US9872854 | Methods for the treatment of psoriatic arthritis using apremilast | May 29, 2034 | Amgen Inc |
Otezla |
US7427638 (Pediatric) | (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione:, and methods of synthesis and compositions thereof | Aug 16, 2028 | Amgen Inc |
Otezla | US7427638 | (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione:, and methods of synthesis and compositions thereof | Feb 16, 2028 | Amgen Inc |
Otezla | US7893101 | Solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions thereof, and uses thereof |
Dec 09, 2023
(Expired) | Amgen Inc |
Otezla | US6962940 | (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof |
Mar 19, 2023
(Expired) | Amgen Inc |
Otezla | US7208516 | Methods of the treatment of psoriatic arthritis using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione |
Mar 19, 2023
(Expired) | Amgen Inc |
Otezla | US7659302 | Methods of using (+)-2-[1-(3-ethoxy-4 methoxyphenyl)-2-methylsulfonylethyl]-4 acetylaminoisoindoline 1,3-dione |
Mar 19, 2023
(Expired) | Amgen Inc |
Otezla | US8455536 | Methods of using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline 1,3-dione |
Mar 19, 2023
(Expired) | Amgen Inc |
Otezla | US8802717 | Methods of treating arthritic conditions using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline 1,3-dione |
Mar 19, 2023
(Expired) | Amgen Inc |
Otezla | US9018243 | Solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions thereof, and uses thereof |
Mar 19, 2023
(Expired) | Amgen Inc |
Otezla | US9724330 | Methods of using (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione |
Mar 19, 2023
(Expired) | Amgen Inc |
Otezla | US6020358 | Substituted phenethylsulfones and method of reducing TNFα levels |
Oct 30, 2018
(Expired) | Amgen Inc |
Apremilast's Family Patents

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