Aprepitant Patent Expiration

Aprepitant is Used for preventing and treating nausea and vomiting associated with chemotherapy, postoperative nausea and vomiting, and emesis induced by cancer chemotherapeutic agents. It was first introduced by Merck And Co Inc in its drug Emend on Mar 26, 2003. Other drugs containing Aprepitant are Cinvanti, Aponvie. 6 different companies have introduced drugs containing Aprepitant.


Aprepitant Patents

Given below is the list of patents protecting Aprepitant, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Aponvie US10500208 Emulsion formulations of aprepitant Sep 18, 2035 Heron Theraps Inc
Aponvie US10624850 Emulsion formulations of an NK-1 receptor antagonist and uses thereof Sep 18, 2035 Heron Theraps Inc
Aponvie US10953018 Emulsion formulations of aprepitant Sep 18, 2035 Heron Theraps Inc
Aponvie US11173118 Emulsion formulations of an NK-1 receptor antagonist and uses thereof Sep 18, 2035 Heron Theraps Inc
Aponvie US11744800 Methods of use of emulsion formulations of an NK-1 receptor antagonist Sep 18, 2035 Heron Theraps Inc
Aponvie US11878074 Methods of use of emulsion formulations of an NK-1 receptor antagonist Sep 18, 2035 Heron Theraps Inc
Aponvie US9561229 Emulsion formulations of aprepitant Sep 18, 2035 Heron Theraps Inc
Aponvie US9808465 Emulsion formulations of aprepitant Sep 18, 2035 Heron Theraps Inc
Aponvie US9974742 Emulsion formulations of an NK-1 receptor antagonist and uses thereof Sep 18, 2035 Heron Theraps Inc
Aponvie US9974793 Emulsion formulations of aprepitant Sep 18, 2035 Heron Theraps Inc
Aponvie US9974794 Emulsion formulations of aprepitant Sep 18, 2035 Heron Theraps Inc
Cinvanti US10500208 Emulsion formulations of aprepitant Sep 18, 2035 Heron Theraps Inc
Cinvanti US10624850 Emulsion formulations of an NK-1 receptor antagonist and uses thereof Sep 18, 2035 Heron Theraps Inc
Cinvanti US10953018 Emulsion formulations of aprepitant Sep 18, 2035 Heron Theraps Inc
Cinvanti US11173118 Emulsion formulations of an NK-1 receptor antagonist and uses thereof Sep 18, 2035 Heron Theraps Inc
Cinvanti US11744800 Methods of use of emulsion formulations of an NK-1 receptor antagonist Sep 18, 2035 Heron Theraps Inc
Cinvanti US9561229 Emulsion formulations of aprepitant Sep 18, 2035 Heron Theraps Inc
Cinvanti US9808465 Emulsion formulations of aprepitant Sep 18, 2035 Heron Theraps Inc
Cinvanti US9974742 Emulsion formulations of an NK-1 receptor antagonist and uses thereof Sep 18, 2035 Heron Theraps Inc
Cinvanti US9974793 Emulsion formulations of aprepitant Sep 18, 2035 Heron Theraps Inc
Cinvanti US9974794 Emulsion formulations of aprepitant Sep 18, 2035 Heron Theraps Inc
Emend US8258132 Pharmaceutical composition of a tachykinin receptor antagonist Sep 26, 2027 Merck
Emend US8258132 Pharmaceutical composition of a tachykinin receptor antagonist Sep 26, 2027 Msd Merck Co
Emend US6096742 Polymorphic form of a tachykinin receptor antagonist Jul 01, 2018

(Expired)

Merck
Emend US6096742 Polymorphic form of a tachykinin receptor antagonist Jul 01, 2018

(Expired)

Msd Merck Co
Emend US5719147 Morpholine and thiomorpholine tachykinin receptor antagonists Apr 17, 2015

(Expired)

Merck
Emend US5538982 Medical use for tachykinin antagonists Jul 23, 2013

(Expired)

Merck
Emend US7214692 Medical use for tachykinin antagonists Sep 18, 2012

(Expired)

Merck



Aprepitant's Family Patents

Family Patents

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Aprepitant Generic API Manufacturers

Several generic applications have been filed for Aprepitant. The first generic version for Aprepitant was by Sandoz Inc and was approved on Sep 24, 2012. And the latest generic version is by Torrent Pharma Inc and was approved on Oct 21, 2020.

Given below is the list of companies who have filed for Aprepitant generic, along with the locations of their manufacturing plants worldwide.


1. GLENMARK SPECLT

Glenmark Specialty Sa has filed for 3 different strengths of generic version for Aprepitant. Given below are the details of the strengths of this generic introduced by Glenmark Speclt.

Strength Dosage Form Availability Application Pathway TE code Launch Date
80MG

capsule Prescription ORAL AB Oct 12, 2017
40MG

capsule Prescription ORAL AB Oct 12, 2017
125MG

capsule Prescription ORAL AB Oct 12, 2017





2. SANDOZ

Sandoz Inc has filed for 3 different strengths of generic version for Aprepitant. Given below are the details of the strengths of this generic introduced by Sandoz.

Strength Dosage Form Availability Application Pathway TE code Launch Date
40MG

capsule Prescription ORAL AB Sep 24, 2012
80MG

capsule Prescription ORAL AB Sep 24, 2012
125MG

capsule Prescription ORAL AB Sep 24, 2012


Manufacturing Plant Locations
New

Sandoz's manufacturing plants are situated in 4 countries - Austria, United States, Spain, India. Given below are the details of these plant locations as well as the firm names of Sandoz as present at those locations.

Country City Firm Name
Austria
Kundl Sandoz GmbH
Langkampfen Sandoz GmbH
United States
Princeton Sandoz Inc
East Hanover Sandoz Incorporated
Spain
Palafolls Sandoz Industrial Products, S.A.
Les Franqueses Del Valles Sandoz Industrial Products S.A.
India
Navi Mumbai Sandoz Private Limited





3. TORRENT

Torrent Pharma Inc has filed for 3 different strengths of generic version for Aprepitant. Given below are the details of the strengths of this generic introduced by Torrent.

Strength Dosage Form Availability Application Pathway TE code Launch Date
40MG

capsule Prescription ORAL AB Oct 21, 2020
80MG

capsule Prescription ORAL AB Oct 21, 2020
125MG

capsule Prescription ORAL AB Oct 21, 2020


Manufacturing Plant Locations
New

Torrent's manufacturing plants are situated in 2 countries - India, United States. Given below are the details of these plant locations as well as the firm names of Torrent as present at those locations.

Country City Firm Name
India
Bharuch Torrent Pharmaceuticals Limited
Pithampur Torrent Pharmaceuticals Limited
Indrad Torrent Pharmaceuticals Limited
Gandhi Nagar Torrent Pharmaceuticals Limited
Thanam Torrent Pharmaceuticals Limited
United States
Kalamazoo Torrent Pharma Inc.
Basking Ridge Torrent Pharma Inc.