Apixaban Patent Expiration

Apixaban is Used for reducing the risk of stroke and systemic embolism. It was first introduced by Bristol Myers Squibb Co Pharmaceutical Research Institute in its drug Eliquis on Dec 28, 2012. Another drug containing Apixaban is Eliquis Sprinkle. 15 different companies have introduced drugs containing Apixaban.


Apixaban Patents

Given below is the list of patents protecting Apixaban, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Eliquis Sprinkle US11896586

(Pediatric)

Apixaban formulations May 22, 2041 Bristol
Eliquis Sprinkle US11896586 Apixaban formulations Nov 22, 2040 Bristol
Eliquis US9326945

(Pediatric)

Apixaban formulations Aug 24, 2031 Bristol Myers Squibb
Eliquis US9326945 Apixaban formulations Feb 24, 2031 Bristol Myers Squibb
Eliquis US6967208

(Pediatric)

Lactam-containing compounds and derivatives thereof as factor Xa inhibitors May 21, 2027 Bristol Myers Squibb
Eliquis Sprinkle US6967208

(Pediatric)

Lactam-containing compounds and derivatives thereof as factor Xa inhibitors May 21, 2027 Bristol
Eliquis US6967208 Lactam-containing compounds and derivatives thereof as factor Xa inhibitors Nov 21, 2026 Bristol Myers Squibb
Eliquis Sprinkle US6967208 Lactam-containing compounds and derivatives thereof as factor Xa inhibitors Nov 21, 2026 Bristol
Eliquis US6413980 Nitrogen containing heterobicycles as factor Xa inhibitors Dec 22, 2019

(Expired)

Bristol Myers Squibb



Apixaban's Family Patents

Family Patents

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Apixaban Generic API Manufacturers

Several generic applications have been filed for Apixaban. The first generic version for Apixaban was by Mylan Pharmaceuticals Inc and was approved on Dec 23, 2019. And the latest generic version is by Macleods Pharmaceuticals Ltd and was approved on Feb 27, 2025.

Given below is the list of companies who have filed for Apixaban generic, along with the locations of their manufacturing plants worldwide.


Apixaban News

The leading 10 medications based on patent numbers: The rise of biologics in creating 'platform empires' compared to small molecules...

26 Jun, 2025

Bristol-Myers Squibb prevails in legal battle with Sandoz regarding apixaban/Eliquis - JUVE Patent

06 Nov, 2024

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