Amprenavir Patent Expiration

Amprenavir is Used for managing HIV infection. It was first introduced by Glaxosmithkline in its drug Agenerase on Apr 15, 1999.


Amprenavir Patents

Given below is the list of patents protecting Amprenavir, along with the drug name that holds that patent and the company name owning that drug.

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Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Agenerase US6730679 Pharmaceutical formulations Nov 11, 2017

(Expired)

Glaxosmithkline
Agenerase US5723490 THF-containing sulfonamide inhibitors of aspartyl protease Mar 03, 2015

(Expired)

Glaxosmithkline
Agenerase US5646180 Treatment of the CNS effects of HIV Jul 08, 2014

(Expired)

Glaxosmithkline
Agenerase US5585397 Sulfonamide inhibitors of aspartyl protease Dec 17, 2013

(Expired)

Glaxosmithkline



Amprenavir's Family Patents

Family Patents

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Clinical Trials

Recent Clinical Trials on Amprenavir:

Sometimes companies keep conducting clinical trials even after the drug's approval to discover new formulations, methods of use, or new treatment indications, so they could file for additional patents or receive regulatory exclusivity extensions, such as pediatric exclusivity, potentially delaying generic competition. Based on these recent clinical trials, generic companies need to consider the potential for new intellectual property or regulatory hurdles. These strategic moves by the drug owner might delay generic substitution or lead to additional sales of the brand drug, even after patent expiry.

Title Lead Sponsor Collaborators Status Phases
Clinical Trials
Fosamprenavir for Laryngopharyngeal Upper Airway Tissue Treatment and Enzyme Reduction Medical College of Wisconsin NA RECRUITING
(Sep 1, 2026)
PHASE2
Oral Fosamprenavir for GERD Medical College of Wisconsin NA NOT YET RECRUITING
(Sep 1, 2026)
PHASE2
Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With a Complicated Regimen Gilead Sciences NA ACTIVE NOT RECRUITING
(Aug 1, 2026)
PHASE2, PHASE3
Salvage Therapy With Amprenavir, Lopinavir and Ritonavir in HIV-infected Patients in Virological Failure. ANRS, Emerging Infectious Diseases NA COMPLETED
(Jun 1, 2026)
PHASE2


Amprenavir Generic API Manufacturers

Given below is the list of companies who have filed for Amprenavir generic, along with the locations of their manufacturing plants worldwide.