Alvimopan Patent Expiration
Alvimopan is Used for accelerating gastrointestinal recovery following bowel resection surgeries. It was first introduced by Cubist Pharmaceuticals Inc
Alvimopan Patents
Given below is the list of patents protecting Alvimopan, along with the drug name that holds that patent and the company name owning that drug.
| Drug Used in | Drug Patent Number | Drug Patent Title | Drug Patent Expiry | Drug Owner |
|---|---|---|---|---|
| Entereg | US8112290 | Methods for delivering a drug to a hospital patient for short-term use while minimizing long-term use of the drug | Jul 31, 2030 | Cubist Pharms |
| Entereg | US8946262 | Methods of preventing and treating gastrointestinal dysfunction | Feb 12, 2030 | Cubist Pharms |
| Entereg | US8645160 | Methods for delivering a drug to a hospital patient for short-term use while minimizing long-term use of the drug | Jun 18, 2029 | Cubist Pharms |
| Entereg | US6469030 | Methods for the treatment and prevention of ileus |
Nov 29, 2020
(Expired) | Cubist Pharms |
| Entereg | US5250542 | Peripherally selective piperidine carboxylate opioid antagonists |
Mar 29, 2016
(Expired) | Cubist Pharms |
| Entereg | US5434171 | Preparation of 3,4,4-trisubstituted-piperidinyl-N-alkylcarboxylates and intermediates |
Dec 08, 2013
(Expired) | Cubist Pharms |
Alvimopan's Family Patents
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Clinical Trials
Recent Clinical Trials on Alvimopan:
Sometimes companies keep conducting clinical trials even after the drug's approval to discover new formulations, methods of use, or new treatment indications, so they could file for additional patents or receive regulatory exclusivity extensions, such as pediatric exclusivity, potentially delaying generic competition. Based on these recent clinical trials, generic companies need to consider the potential for new intellectual property or regulatory hurdles. These strategic moves by the drug owner might delay generic substitution or lead to additional sales of the brand drug, even after patent expiry.
| Title | Lead Sponsor | Collaborators | Status | Phases |
|---|---|---|---|---|
 | ||||
| A Study of Surgical Techniques During Cystectomy | Memorial Sloan Kettering Cancer Center | NA |
RECRUITING
(Sep 1, 2026)
| PHASE3 |
| Effect of Naloxegol on Postoperative Ileus in Patients Undergoing Cardiac Surgery | CMC Ambroise Paré | NA |
COMPLETED
(May 1, 2026)
| PHASE3 |