List of Leqvio drug patents

Leqvio is owned by Novartis.

Leqvio contains Inclisiran Sodium.

Leqvio has a total of 20 drug patents out of which 4 drug patents have expired.

Expired drug patents of Leqvio are:

  • US10590418
  • US9074213
  • US8546143
  • US8232383

Leqvio was authorised for market use on 22 December, 2021.

Leqvio is available in solution;subcutaneous dosage forms.

Leqvio can be used as as an adjunct to diet and maximally tolerated statin therapy for the treatment of adults with heterozygous familial hypercholesterolemia (hefh) or clinical atherosclerotic cardiovascular disease (ascvd), by inhibiting expression of the pcsk9 gene.

Drug patent challenges can be filed against Leqvio from 2025-12-22.

The generics of Leqvio are possible to be released after 25 August, 2036.

LEQVIO's oppositions filed in EPO
LEQVIO Litigations
Can you believe LEQVIO received compensation for the extended wait time during the regulatory approval process?
Patent Number Company Patent Title Patent Expiry Activity Alert
These patents protects the active chemical substance. Only patent owner can launch products that use this active substance.
US9074213 NOVARTIS Compositions and methods for inhibiting expression of a target gene
Mar, 2022

(1 year, 2 months ago)

US8546143 NOVARTIS Compositions and methods for inhibiting expression of a target gene
Apr, 2022

(1 year, 1 month ago)

US8232383 NOVARTIS RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
Feb, 2023

(3 months ago)

US11078485 NOVARTIS Compositions comprising alternating 2′-modified nucleosides for use in gene modulation
Nov, 2023

(4 months from now)

US9708610 NOVARTIS Compositions comprising alternating 2′-modified nucleosides for use in gene modulation
Jan, 2024

(6 months from now)

US9708615 NOVARTIS Therapeutic compositions
Mar, 2024

(9 months from now)

US10669544 NOVARTIS Therapeutic compositions
Mar, 2024

(9 months from now)

US10273477 NOVARTIS Therapeutic compositions
Mar, 2024

(9 months from now)

US11530408 NOVARTIS Therapeutic compositions
May, 2024

(11 months from now)

US8809292 NOVARTIS Compositions and methods for inhibiting expression of the PCSK9 gene
May, 2027

(3 years from now)

US10131907 NOVARTIS Glycoconjugates of RNA interference agents
Aug, 2028

(5 years from now)

US8828956 NOVARTIS Carbohydrate conjugates as delivery agents for oligonucleotides
Dec, 2028

(5 years from now)

US9370582 NOVARTIS Carbohydrate conjugates as delivery agents for oligonucleotides
Dec, 2028

(5 years from now)

US10806791 NOVARTIS Carbohydrate conjugates as delivery agents for oligonucleotides
Dec, 2028

(5 years from now)

US8106022 NOVARTIS Carbohydrate conjugates as delivery agents for oligonucleotides
Dec, 2029

(6 years from now)

US10125369 NOVARTIS PCSK9 iRNA compositions and methods of use thereof
Aug, 2034

(11 years from now)

These patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US10590418 NOVARTIS Methods and compositions for RNAi mediated inhibition of gene expression in mammals
Jul, 2022

(10 months ago)

US10266825 NOVARTIS Compositions comprising alternating 2′-modified nucleosides for use in gene modulation
Nov, 2023

(4 months from now)

US8222222 NOVARTIS Compositions and methods for inhibiting expression of the PCSK9 gene
Dec, 2027

(4 years from now)

US10851377 NOVARTIS Methods and compositions for treating a proprotein convertase subtilisin kexin (PCSK9) gene-associated disorder
Aug, 2036

(13 years from now)

Do you want to check out LEQVIO patents from before 2022?
Exclusivity Exclusivity Expiration
New Chemical Entity Exclusivity (NCE) Dec 22, 2026

Drugs and Companies using INCLISIRAN SODIUM ingredient

NCE-1 date: 2025-12-22

Market Authorisation Date: 22 December, 2021

Treatment: As an adjunct to diet and maximally tolerated statin therapy for the treatment of adults with heterozygous familial hypercholesterolemia (hefh) or clinical atherosclerotic cardiovascular disease (ascv...

Dosage: SOLUTION;SUBCUTANEOUS

More Information on Dosage

LEQVIO family patents

815

United States

184

European Union

139

Australia

126

Japan

86

Canada

31

Germany

18

Spain

18

Austria

18

China

15

Denmark

13

United Kingdom

13

Mexico

12

Hong Kong

9

Portugal

8

Korea, Republic of

6

Israel

6

Cyprus

EA

5

EA

5

New Zealand

4

South Africa

3

Poland

3

Norway

3

Slovenia

3

Brazil

3

Hungary

2

Russia

2

Lithuania

1

Luxembourg

1

Croatia

IB

1

IB

1

Netherlands

1

Indonesia

1

Chile

1

Singapore

1

Argentina

1

RS

900+ leading pharmaceutical companies are staying up-to-date with drug patents through Pharsight

Join them to stay ahead in capturing the next drug going generic

Other things you might be interested in