Agios Drug Patent Portfolio

Agios owns 2 orange book drugs protected by 10 US patents Given below is the list of Agios's drug patents along with their expiration dates.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US11878049 Mitapivat therapy and modulators of cytochrome P450 31 Jul, 2041
Active
US11254652 Crystalline forms of N-(4-(4-(cyclopropymethyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide 21 Nov, 2038
Active
US11234976 Methods of using pyruvate kinase activators 11 Oct, 2038
Active
US11793806 Pyruvate kinase activators for use in therapy 12 Apr, 2033
Active
US9193701 Pyruvate kinase activators for use in therapy 26 Oct, 2032
Active
US10632114 Pyruvate kinase activators for use in therapy 03 May, 2032
Active
US9682080 Pyruvate kinase activators for use in therapy 03 May, 2032
Active
US9980961 Pyruvate kinase activators for use in therapy 03 May, 2032
Active
USRE49582 Therapeutic compounds and compositions 24 Feb, 2031
Active
US8785450 Therapeutic compounds and compositions 24 Feb, 2031
Active


Given below is the list of recent legal activities going on the following drug patents of Agios.

Activity Date Patent Number
Patent litigations
Payment of Maintenance Fee, 4th Year, Large Entity 22 Aug, 2025 US11254652
Payment of Maintenance Fee, 4th Year, Large Entity 22 Aug, 2025 US11254652
Payment of Maintenance Fee, 4th Year, Large Entity 01 Aug, 2025 US11234976
Mail Patent eCofC Notification 01 Jul, 2025 US11254652
Email Notification 01 Jul, 2025 US11254652
Patent eCofC Notification 01 Jul, 2025 US11254652
Recordation of Patent eCertificate of Correction 01 Jul, 2025 US11254652
Mail Patent eCofC Notification 01 Jul, 2025 US11254652
Recordation of Patent eCertificate of Correction 01 Jul, 2025 US11254652
Email Notification 01 Jul, 2025 US11254652
Patent eCofC Notification 01 Jul, 2025 US11254652
Withdrawal of Application for PTE 25 Jun, 2025 US9193701
Withdrawal of Application for PTE 25 Jun, 2025 US9193701
Post Issue Communication - Certificate of Correction 13 Jun, 2025 US11254652
Post Issue Communication - Certificate of Correction 13 Jun, 2025 US11254652


Agios's Family Patents

Agios drugs have patent protection in a total of 42 countries. It's US patent count contributes only to 20.7% of its total global patent coverage. 5 countries have all of their patents expired or invalidated which has opened up potential generic launch opportunities in these countries. Click below to unlock the full patent family tree.

Family Patents



Agios Drug List

Given below is the complete list of Agios's drugs and the patents protecting them.


1. Aqvesme

Aqvesme is protected by 6 patents, out of which none have expired yet. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US11878049 Mitapivat therapy and modulators of cytochrome P450 31 Jul, 2041
(15 years from now)
Active
US11254652 Crystalline forms of N-(4-(4-(cyclopropymethyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide 21 Nov, 2038
(12 years from now)
Active
US9193701 Pyruvate kinase activators for use in therapy 26 Oct, 2032
(6 years from now)
Active
US10632114 Pyruvate kinase activators for use in therapy 03 May, 2032
(6 years from now)
Active
US9682080 Pyruvate kinase activators for use in therapy 03 May, 2032
(6 years from now)
Active
USRE49582 Therapeutic compounds and compositions 24 Feb, 2031
(4 years from now)
Active

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Aqvesme's drug page


2. Pyrukynd

Pyrukynd is protected by 10 patents, out of which none have expired yet. Check out its patent list below.

Drug Patent Number Drug Patent Title Drug Patent Expiry Status
US11878049 Mitapivat therapy and modulators of cytochrome P450 31 Jul, 2041
(15 years from now)
Active
US11254652 Crystalline forms of N-(4-(4-(cyclopropymethyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide 21 Nov, 2038
(12 years from now)
Active
US11234976 Methods of using pyruvate kinase activators 11 Oct, 2038
(12 years from now)
Active
US11793806 Pyruvate kinase activators for use in therapy 12 Apr, 2033
(7 years from now)
Active
US9193701 Pyruvate kinase activators for use in therapy 26 Oct, 2032
(6 years from now)
Active
US10632114 Pyruvate kinase activators for use in therapy 03 May, 2032
(6 years from now)
Active
US9682080 Pyruvate kinase activators for use in therapy 03 May, 2032
(6 years from now)
Active
US9980961 Pyruvate kinase activators for use in therapy 03 May, 2032
(6 years from now)
Active
US8785450 Therapeutic compounds and compositions 24 Feb, 2031
(4 years from now)
Active
USRE49582 Therapeutic compounds and compositions 24 Feb, 2031
(4 years from now)
Active

Discover which of these patents contain the active ingredient(API) of the drug, their family patents, along with litigation and legal activity details of these patents on Pyrukynd's drug page


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