Resistant Hypertension With Comorbidities Therapeutics

1. Benicar patent expiration

Treatment: Use as an antihypertensive agent; Treatment of hypertension

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US5616599 COSETTE Angiotensin II antagosist 1-biphenylmethylimidazole compounds and their therapeutic use
Apr, 2016

(9 years ago)

US6878703 COSETTE Pharmaceutical composition
Nov, 2021

(4 years ago)

US6878703

(Pediatric)

COSETTE Pharmaceutical composition
May, 2022

(3 years ago)

US5616599

(Pediatric)

COSETTE Angiotensin II antagosist 1-biphenylmethylimidazole compounds and their therapeutic use
Oct, 2016

(9 years ago)




Drug Exclusivity Drug Exclusivity Expiration
New Patient Population(NPP) Feb 04, 2013
Pediatric Exclusivity(PED) Aug 04, 2013

Drugs and Companies using OLMESARTAN MEDOXOMIL ingredient

Market Authorisation Date: 25 April, 2002

Dosage: TABLET

How can I launch a generic of BENICAR before it's drug patent expiration?
More Information on Dosage

BENICAR family patents

Family Patents

2. Edarbi patent expiration

Treatment: Treatment of hypertension

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents protects the active chemical substance. Only drug patent owner can launch products that use this active substance.
US7157584 AZURITY Benzimidazole derivative and use thereof
May, 2025

(7 months ago)

These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US5583141 AZURITY Heterocyclic compounds and their use as angiotensin antagonists
Dec, 2013

(12 years ago)

US5958961 AZURITY Pharmaceutical composition for angiotensin II-mediated diseases
Jun, 2014

(11 years ago)

US7572920 AZURITY Benzimidazole derivative and use as a II receptor antagonist
Jan, 2025

(1 year, 1 day ago)

US9066936 AZURITY Solid pharmaceutical composition comprising a benzimidazole-7-carboxylate derivative and a pH control agent
Mar, 2028

(2 years from now)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Feb 25, 2016

Drugs and Companies using AZILSARTAN KAMEDOXOMIL ingredient

NCE-1 date: 25 February, 2015

Market Authorisation Date: 25 February, 2011

Dosage: TABLET

How can I launch a generic of EDARBI before it's drug patent expiration?
More Information on Dosage

EDARBI family patents

Family Patents

Stay ahead of others in designing the generic launch strategy of these 5 blockbuster drugs expiring in next 5 years.

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3. Inspra patent expiration

Treatment: Treatment of conditions for which an aldosterone receptor blocker is indicated, such as hypertension, heart failure, and post-myocardial infarction; Use of eplerenone in combination with an angiotensi...

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US6863902 UPJOHN Immediate release eplerenone compositions
Apr, 2020

(5 years ago)

US6558707

(Pediatric)

UPJOHN Immediate release eplerenone compositions
Jun, 2020

(5 years ago)

US6747020

(Pediatric)

UPJOHN Methods of treating heart failure and hypertension using combinations of eplerenone and an angiotensin converting enzyme inhibitor
May, 2020

(5 years ago)

US7157101

(Pediatric)

UPJOHN Micronized eplerenone compositions
Jun, 2020

(5 years ago)

US6495165

(Pediatric)

UPJOHN Eplerenone compositions having improved bioavailability
Jun, 2020

(5 years ago)

US6410524

(Pediatric)

UPJOHN Combination therapy of angiotensin converting enzyme inhibitor and aldosterone antagonist for reducing morbidity and mortality from cardiovascular disease
May, 2020

(5 years ago)

US6410054

(Pediatric)

UPJOHN Immediate release eplerenone compositions
Jun, 2020

(5 years ago)

US6534093

(Pediatric)

UPJOHN Immediate release eplerenone compositions
Jun, 2020

(5 years ago)

US6863902

(Pediatric)

UPJOHN Immediate release eplerenone compositions
Oct, 2020

(5 years ago)

US6410524 UPJOHN Combination therapy of angiotensin converting enzyme inhibitor and aldosterone antagonist for reducing morbidity and mortality from cardiovascular disease
Nov, 2019

(6 years ago)

US6410054 UPJOHN Immediate release eplerenone compositions
Dec, 2019

(6 years ago)

US6747020 UPJOHN Methods of treating heart failure and hypertension using combinations of eplerenone and an angiotensin converting enzyme inhibitor
Nov, 2019

(6 years ago)

US6534093 UPJOHN Immediate release eplerenone compositions
Dec, 2019

(6 years ago)

US7157101 UPJOHN Micronized eplerenone compositions
Dec, 2019

(6 years ago)

US6495165 UPJOHN Eplerenone compositions having improved bioavailability
Dec, 2019

(6 years ago)

US6558707 UPJOHN Immediate release eplerenone compositions
Dec, 2019

(6 years ago)




Drug Exclusivity Drug Exclusivity Expiration
Pediatric Exclusivity(PED) Jul 31, 2011

Drugs and Companies using EPLERENONE ingredient

Market Authorisation Date: 27 September, 2002

Dosage: TABLET

How can I launch a generic of INSPRA before it's drug patent expiration?
More Information on Dosage

INSPRA family patents

Family Patents

4. Tryvio patent expiration

Treatment: Treatment of hypertension in combination with other antihypertensive drugs, including an angiotensin converting enzyme inhibitor, to lower blood pressure in adult patients who are not adequately contr...

Drug Patent Number Company Drug Patent Title Drug Patent Expiry Activity Alert
These drug patents protects the active chemical substance. Only drug patent owner can launch products that use this active substance.
US8324232 IDORSIA 4-pyrimidinesulfamide derivative
Sep, 2029

(3 years from now)

US10919881 IDORSIA Crystalline forms of a 4-pyrimidinesulfamide derivative aprocitentan
Feb, 2038

(12 years from now)

These drug patents focus on the other aspects of the active substance like dosage, mode of administration (oral, tablet, capsules, liquids etc).
US11787782 IDORSIA Combinations of a 4-pyrimidinesulfamide derivative with active ingredients for the treatment of endothelin related diseases
Mar, 2038

(12 years from now)

US11680058 IDORSIA Crystalline forms of a 4-pyrimidinesulfamide derivative aprocitentan
Jul, 2038

(12 years from now)

US11174247 IDORSIA Combinations of a 4-pyrimidinesulfamide derivative with active ingredients for the treatment of endothelin related diseases
Nov, 2037

(11 years from now)

US12297189 IDORSIA Crystalline forms of a 4-pyrimidinesulfamide derivative aprocitentan
Feb, 2038

(12 years from now)




Drug Exclusivity Drug Exclusivity Expiration
New Chemical Entity Exclusivity(NCE) Mar 22, 2029

Drugs and Companies using APROCITENTAN ingredient

NCE-1 date: 22 March, 2028

Market Authorisation Date: 19 March, 2024

Dosage: TABLET

More Information on Dosage

TRYVIO family patents

Family Patents