Ziftomenib Patent Expiration

Ziftomenib was first introduced by Kura Oncology Inc in its drug Komzifti on Nov 13, 2025.


Ziftomenib Patents

Given below is the list of patents protecting Ziftomenib, along with the drug name that holds that patent and the company name owning that drug.

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Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Komzifti US12410184 Crystalline Forms Of A Menin Inhibitor Jul 16, 2044 Kura
Komzifti US12521396 Pharmaceutical Compositions Comprising A Menin Inhibitor Jul 16, 2044 Kura
Komzifti US11944627 Methods For Treating Hematological Malignancies And Ewing'S Sarcoma Sep 06, 2038 Kura
Komzifti US10781218 Substituted Inhibitors Of Menin-Mll And Methods Of Use Mar 15, 2037 Kura
Komzifti US11673898 Substituted Inhibitors Of Menin-Mll And Methods Of Use Mar 15, 2037 Kura
Komzifti US10869868 Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression In Npm1 Mutant Leukemia Jan 26, 2037 Kura
Komzifti US10077271 Methods And Compositions For Inhibiting The Interaction Of Menin With Mll Proteins Mar 16, 2036 Kura
Komzifti US10174041 Methods And Compositions For Inhibiting The Interaction Of Menin With Mll Proteins Mar 16, 2036 Kura



Ziftomenib's Family Patents

Family Patents

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Clinical Trials

Recent Clinical Trials on Ziftomenib:

Sometimes companies keep conducting clinical trials even after the drug's approval to discover new formulations, methods of use, or new treatment indications, so they could file for additional patents or receive regulatory exclusivity extensions, such as pediatric exclusivity, potentially delaying generic competition. Based on these recent clinical trials, generic companies need to consider the potential for new intellectual property or regulatory hurdles. These strategic moves by the drug owner might delay generic substitution or lead to additional sales of the brand drug, even after patent expiry.

Title Lead Sponsor Collaborators Status Phases
Clinical Trials
Dose Escalation and Expansion of Ziftomenib in Combination With Quizartinib in Acute Myeloid Leukemia M.D. Anderson Cancer Center NA RECRUITING
(Sep 1, 2026)
PHASE1
A Phase 2 Clinical Study of Ziftomenib in Patients With Relapsed or Refractory NPM1-Mutated Acute Myeloid Leukemia Kyowa Kirin Co., Ltd. NA RECRUITING
(May 1, 2026)
PHASE2
Ziftomenib Maintenance Post Allo-HCT Massachusetts General Hospital NA RECRUITING
(Mar 1, 2026)
PHASE1


Ziftomenib Generic API Manufacturers

Given below is the list of companies who have filed for Ziftomenib generic, along with the locations of their manufacturing plants worldwide.