Tucatinib Patent Expiration

Tucatinib is Used for treating advanced or metastatic colorectal cancer and breast cancer that is HER2-positive or overexpressing. It was first introduced by Seagen Inc in its drug Tukysa on Apr 17, 2020.


Tucatinib Patents

Given below is the list of patents protecting Tucatinib, along with the drug name that holds that patent and the company name owning that drug.

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Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Tukysa US11207324 Treatment of HER2 positive cancers Apr 27, 2038 Seagen
Tukysa US11666572 Treatment of HER2 positive cancers Apr 27, 2038 Seagen
Tukysa US12048698 Treatment of HER2 positive cancers Apr 27, 2038 Seagen
Tukysa US11504370 Treatment of brain cancer Mar 25, 2033 Seagen
Tukysa US9457093 Solid dispersions of a ERB2 (HER2) inhibitor Oct 12, 2032 Seagen
Tukysa US8648087 N4-phenyl-quinazoline-4-amine derivatives and related compounds as ErbB type I receptor tyrosine kinase inhibitors for the treatment of hyperproliferative diseases Jan 14, 2031 Seagen
Tukysa US9693989 N4-phenyl-quinazoline-4-amine derivatives and related compounds as ErbB type I receptor tyrosine kinase inhibitors for the treatment of hyperproliferative diseases May 09, 2027 Seagen
Tukysa US7452895 Quinazoline analogs as receptor tyrosine kinase inhibitors Nov 16, 2026 Seagen



A patent's expiry date may change depending upon legal activities going on that patent. Critical activities like abandoning of a patent, term extension of a patent or amendment of its claims can increase or decrease the life of a patent hence affecting its expiry date and in turn affecting the generic launch date of that drug. Tracking these ongoing activities on a patent application helps to keep an eye on the latest developments in the patent process of the drug which can give an idea of how early a drug's generic could be available. The next section provides a list of recent legal activities on Tucatinib's patents.

Given below is the list recent legal activities going on the following patents of Tucatinib.

Activity Date Patent Number
Patent litigations
Payment of Maintenance Fee, 12th Year, Large Entity 10 Jul, 2025 US8648087
Payment of Maintenance Fee, 4th Year, Large Entity 17 Jan, 2025 US11207324
FDA Final Eligibility Letter 13 Jan, 2025 US8648087
FDA Final Eligibility Letter 13 Jan, 2025 US9457093
FDA Final Eligibility Letter 13 Jan, 2025 US9693989
FDA Final Eligibility Letter 13 Jan, 2025 US7452895
Correspondence Address Change 18 Dec, 2024 US11666572
Correspondence Address Change 18 Dec, 2024 US11207324
Change in Power of Attorney (May Include Associate POA) 17 Dec, 2024 US9457093
Email Notification 17 Dec, 2024 US8648087


Tucatinib's Family Patents

Family Patents

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Tucatinib Generic API Manufacturers

Given below is the list of companies who have filed for Tucatinib generic, along with the locations of their manufacturing plants worldwide.