Tofacitinib Citrate Patent Expiration

Tofacitinib Citrate is Used for treating moderate to severe ulcerative colitis and rheumatoid arthritis. It was first introduced by Pf Prism Cv in its drug Xeljanz on Nov 6, 2012. Another drug containing Tofacitinib Citrate is Xeljanz Xr. 8 different companies have introduced drugs containing Tofacitinib Citrate.


Tofacitinib Citrate Patents

Given below is the list of patents protecting Tofacitinib Citrate, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Xeljanz Xr US10639309

(Pediatric)

Tofacitinib oral sustained release dosage forms Sep 14, 2034 Pfizer
Xeljanz Xr US11253523

(Pediatric)

Tofacitinib oral sustained release dosage forms Sep 14, 2034 Pfizer
Xeljanz Xr US9937181

(Pediatric)

Tofacitinib oral sustained release dosage forms Sep 14, 2034 Pfizer
Xeljanz Xr US10639309 Tofacitinib oral sustained release dosage forms Mar 14, 2034 Pfizer
Xeljanz Xr US11253523 Tofacitinib oral sustained release dosage forms Mar 14, 2034 Pfizer
Xeljanz Xr US9937181 Tofacitinib oral sustained release dosage forms Mar 14, 2034 Pfizer
Xeljanz USRE41783

(Pediatric)

Pyrrolo[2,3-D]pyrimidine compounds Jun 08, 2026 Pfizer
Xeljanz USRE41783

(Pediatric)

Pyrrolo[2,3-D]pyrimidine compounds Jun 08, 2026 Pf Prism Cv
Xeljanz Xr USRE41783

(Pediatric)

Pyrrolo[2,3-D]pyrimidine compounds Jun 08, 2026 Pfizer
Xeljanz USRE41783 Pyrrolo[2,3-D]pyrimidine compounds Dec 08, 2025 Pfizer
Xeljanz USRE41783 Pyrrolo[2,3-D]pyrimidine compounds Dec 08, 2025 Pf Prism Cv
Xeljanz Xr USRE41783 Pyrrolo[2,3-D]pyrimidine compounds Dec 08, 2025 Pfizer
Xeljanz US6965027 Crystalline 3-{4-methyl-3-[methyl-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amino]-piperidin-1-yl}-3-oxo-propionitrile citrate Mar 25, 2023

(Expired)

Pf Prism Cv
Xeljanz US6965027 Crystalline 3-{4-methyl-3-[methyl-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amino]-piperidin-1-yl}-3-oxo-propionitrile citrate Mar 25, 2023

(Expired)

Pf Prism Cv
Xeljanz Xr US6956027 N-terminally chemically modified protein compositions and methods Mar 25, 2023

(Expired)

Pfizer
Xeljanz Xr US6965027 Crystalline 3-{4-methyl-3-[methyl-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amino]-piperidin-1-yl}-3-oxo-propionitrile citrate Mar 25, 2023

(Expired)

Pfizer
Xeljanz US7301023 Chiral salt resolution May 23, 2022

(Expired)

Pf Prism Cv
Xeljanz US6956041 Pyrrolo[2,3-d]pyrimidine compounds Dec 08, 2020

(Expired)

Pf Prism Cv
Xeljanz US7091208 Pyrrolo[2,3-D]pyrimidine compounds Dec 08, 2020

(Expired)

Pf Prism Cv
Xeljanz US7265221 Pyrrolo[2,3-d]pyrimidine compounds Dec 08, 2020

(Expired)

Pf Prism Cv
Xeljanz US7265221 Pyrrolo[2,3-d]pyrimidine compounds Dec 08, 2020

(Expired)

Pf Prism Cv
Xeljanz US7301023 Chiral salt resolution Dec 08, 2020

(Expired)

Pf Prism Cv
Xeljanz US7842699 Pyrrolo[2,3-D]pyrimidine compounds Dec 08, 2020

(Expired)

Pf Prism Cv
Xeljanz Xr US6956041 Pyrrolo[2,3-d]pyrimidine compounds Dec 08, 2020

(Expired)

Pfizer
Xeljanz Xr US7091208 Pyrrolo[2,3-D]pyrimidine compounds Dec 08, 2020

(Expired)

Pfizer
Xeljanz Xr US7265221 Pyrrolo[2,3-d]pyrimidine compounds Dec 08, 2020

(Expired)

Pfizer
Xeljanz Xr US7301023 Chiral salt resolution Dec 08, 2020

(Expired)

Pfizer
Xeljanz Xr US7842699 Pyrrolo[2,3-D]pyrimidine compounds Dec 08, 2020

(Expired)

Pfizer



A patent's expiry date may change depending upon legal activities going on that patent. Critical activities like abandoning of a patent, term extension of a patent or amendment of its claims can increase or decrease the life of a patent hence affecting its expiry date and in turn affecting the generic launch date of that drug. Tracking these ongoing activities on a patent application helps to keep an eye on the latest developments in the patent process of the drug which can give an idea of how early a drug's generic could be available. The next section provides a list of recent legal activities on Tofacitinib Citrate's patents.

Given below is the list recent legal activities going on the following patents of Tofacitinib Citrate.

Activity Date Patent Number
Patent litigations
Payment of Maintenance Fee, 4th Year, Large Entity 12 Oct, 2023 US10639309
Expire Patent 02 Jan, 2023 US7842699
Maintenance Fee Reminder Mailed 18 Jul, 2022 US7842699
Recordation of Patent Grant Mailed 22 Feb, 2022 US11253523
Patent Issue Date Used in PTA Calculation 22 Feb, 2022 US11253523
Email Notification 03 Feb, 2022 US11253523
Issue Notification Mailed 02 Feb, 2022 US11253523
Mailing Corrected Notice of Allowability 27 Jan, 2022 US11253523
Email Notification 27 Jan, 2022 US11253523
Dispatch to FDC 25 Jan, 2022 US11253523


Tofacitinib Citrate's Family Patents

Family Patents

Explore Our Curated Drug Screens

Drugs Generating Over $1 Billion in Annual Revenue
Explore the top-performing drugs that dominate the pharmaceutical industry
View List
NCE-1 Patent Expiry in the Next 1 Year
Identify opportunities as new chemical entity (NCE-1) patents approach expiry
View List
Recently Granted Patents in EP
Find the opportunity to file Oppositions
View List

Tofacitinib Citrate Generic API Manufacturers

Several generic applications have been filed for Tofacitinib Citrate. The first generic version for Tofacitinib Citrate was by Ajanta Pharma Ltd and was approved on Jun 1, 2021. And the latest generic version is by Dexcel Pharma Technologies Ltd and was approved on Dec 16, 2024.

Given below is the list of companies who have filed for Tofacitinib Citrate generic, along with the locations of their manufacturing plants worldwide.