Thalidomide Patent Expiration

Thalidomide is Used for treating multiple myeloma and erythema nodosum leprosum. It was first introduced by Bristol-Myers Squibb Co in its drug Thalomid on Jul 16, 1998. 2 different companies have introduced drugs containing Thalidomide.


Thalidomide Patents

Given below is the list of patents protecting Thalidomide, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Thalomid US5629327 Methods and compositions for inhibition of angiogenesis May 13, 2014

(Expired)

Bristol-myers
Thalomid US6045501 Methods for delivering a drug to a patient while preventing the exposure of a foetus or other contraindicated individual to the drug Aug 28, 2018

(Expired)

Bristol-myers
Thalomid US6235756 Methods and compositions for inhibition of angiogenesis by thalidomide Mar 01, 2013

(Expired)

Bristol-myers
Thalomid US6315720 Methods for delivering a drug to a patient while avoiding the occurrence of an adverse side effect known or suspected of being caused by the drug Oct 23, 2020

(Expired)

Bristol-myers
Thalomid US6561976 Methods for delivering a drug to a patient while preventing the exposure of a foetus or other contraindicated individual to the drug Aug 28, 2018

(Expired)

Bristol-myers
Thalomid US6561977 Methods for delivering a drug to a patient while restricting access to the drug by patients for whom the drug may be contraindicated Oct 23, 2020

(Expired)

Bristol-myers
Thalomid US6755784 Methods for delivering a drug to a patient while restricting access to the drug by patients for whom the drug may be contraindicated Oct 23, 2020

(Expired)

Bristol-myers
Thalomid US6869399 Methods for delivering a drug to a patient while restricting access to the drug by patients for whom the drug may be contraindicated Oct 23, 2020

(Expired)

Bristol-myers
Thalomid US6908432 Methods for delivering a drug to a patient while preventing the exposure of a foetus or other contraindicated individual to the drug Aug 28, 2018

(Expired)

Bristol-myers
Thalomid US7141018 Methods for delivering a drug to a patient while restricting access to the drug by patients for whom the drug may be contraindicated Oct 23, 2020

(Expired)

Bristol-myers
Thalomid US7230012 Pharmaceutical compositions and dosage forms of thalidomide Dec 09, 2023

(Expired)

Bristol-myers
Thalomid US7435745 Methods and compositions for inhibition of angiogenesis Nov 03, 2017

(Expired)

Bristol-myers
Thalomid US7723361 Methods for inhibiting undesired angiogenesis in patients having tumors with thalidomide Mar 01, 2013

(Expired)

Bristol-myers
Thalomid US7874984 Methods for delivering a drug to a patient while preventing the exposure of a foetus or other contraindicated individual to the drug Aug 28, 2018

(Expired)

Bristol-myers
Thalomid US7959566 Methods for delivering a drug to a patient while restricting access to the drug by patients for whom the drug may be contraindicated Oct 23, 2020

(Expired)

Bristol-myers
Thalomid US8143283 Methods for treating blood-born tumors with thalidomide Mar 01, 2013

(Expired)

Bristol-myers
Thalomid US8204763 Methods for delivering a drug to a patient while preventing the exposure of a foetus or other contraindicated individual to the drug Aug 28, 2018

(Expired)

Bristol-myers
Thalomid US8315886 Methods for delivering a drug to a patient while restricting access to the drug by patients for whom the drug may be contraindicated Oct 23, 2020

(Expired)

Bristol-myers
Thalomid US8589188 Methods for delivering a drug to a patient while preventing the exposure of a foetus or other contraindicated individual to the drug Aug 28, 2018

(Expired)

Bristol-myers
Thalomid US8626531 Methods for delivering a drug to a patient while restricting access to the drug by patients for whom the drug may be contraindicated Oct 23, 2020

(Expired)

Bristol-myers


A patent's expiry date may change depending upon legal activities going on that patent. Critical activities like abandoning of a patent, term extension of a patent or amendment of its claims can increase or decrease the life of a patent hence affecting its expiry date and in turn affecting the generic launch date of that drug. Tracking these ongoing activities on a patent application helps to keep an eye on the latest developments in the patent process of the drug which can give an idea of how early a drug's generic could be available. The next section provides a list of recent legal activities on Thalidomide's patents.

Given below is the list recent legal activities going on the following patents of Thalidomide.

Event Date Patent/Publication
Patent litigations
Expire Patent 17 Jul, 2023 US7959566
Expire Patent 27 Feb, 2023 US7874984
Maintenance Fee Reminder Mailed 30 Jan, 2023 US7959566
Maintenance Fee Reminder Mailed 12 Sep, 2022 US7874984
Expire Patent 16 Nov, 2020 US7435745(Litigated)
Maintenance Fee Reminder Mailed 01 Jun, 2020 US7435745(Litigated)
Payment of Maintenance Fee, 8th Year, Large Entity 14 Dec, 2018 US7959566
Payment of Maintenance Fee, 12th Year, Large Entity 12 Dec, 2018 US7230012(Litigated)
Payment of Maintenance Fee, 8th Year, Large Entity 25 Jul, 2018 US7874984
Payment of Maintenance Fee, 12th Year, Large Entity 29 May, 2018 US7141018



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Thalidomide Generics

Only one generic application has been filed for Thalidomide.

Given below is the list of companies who have filed for Thalidomide generic.


1. NATCO

Natco Pharma Ltd has filed for 1 generic for Thalidomide. Given below are the details of the strengths of this generic introduced by Natco.

Strength Dosage Form Availability Application Pathway TE code Launch Date
150MG capsule Discontinued ORAL N/A Apr 27, 2023