Latest Clinical Trials
Phase I Trial of rhIL-15 Plus Dinutuximab Plus Irinotecan/Temozolomide for Children and Young Adults With Relapsed/Refractory Neuroblastoma National Cancer Institute (NCI) NA
RECRUITING
(Sep 22, 2026)
PHASE1 Atezolizumab in Combination With Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma M.D. Anderson Cancer Center NA
COMPLETED
(Sep 1, 2026)
PHASE1, PHASE2 Safety and Immunogenicity of Personalized Genomic Vaccine and Tumor Treating Fields (TTFields) to Treat Glioblastoma Adilia Hormigo NA
ACTIVE NOT RECRUITING
(Sep 1, 2026)
PHASE1 Telaglenastat With Radiation Therapy and Temozolomide in Treating Patients With IDH-Mutated Diffuse Astrocytoma or Anaplastic Astrocytoma National Cancer Institute (NCI) NA
ACTIVE NOT RECRUITING
(Sep 1, 2026)
PHASE1 OKN-007 in Combination With Adjuvant Temozolomide Chemoradiotherapy for Newly Diagnosed Glioblastoma University of Oklahoma NA
ACTIVE NOT RECRUITING
(Sep 1, 2026)
PHASE1 Evaluate the Efficacy and Safety of ADCV01 as an Add-On Treatment for Primary Glioblastoma Multiforme (GBM) Patients Ever Supreme Bio Technology Co., Ltd. NA
RECRUITING
(Sep 1, 2026)
PHASE2 NK Cells Infusions With Irinotecan, Temozolomide, and Dinutuximab Nationwide Children's Hospital NA
ACTIVE NOT RECRUITING
(Sep 1, 2026)
PHASE1, PHASE2 Apatinib Mesylate Combined With IT Regimen for the Treatment of Recurrent or Refractory Neuroblastoma: A Single-arm, Phase I/II,Multi-center, Clinical Study. Sun Yat-sen University NA
COMPLETED
(Sep 1, 2026)
PHASE1, PHASE2 A Dose Finding Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination With Standard of Care and in Recurrent Glioblastoma as a Single Agent. Novartis Pharmaceuticals NA
ACTIVE NOT RECRUITING
(Sep 1, 2026)
PHASE1 Azeliragon and Chemoradiotherapy in Newly Diagnosed Glioblastoma Cantex Pharmaceuticals NA
COMPLETED
(Sep 1, 2026)
PHASE1, PHASE2 A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent Glioma University of Nebraska NA
RECRUITING
(Sep 1, 2026)
PHASE1 A Study of Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma Debiopharm International SA NA
RECRUITING
(Sep 1, 2026)
PHASE1, PHASE2 Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM) NaviFUS Corporation NA
SUSPENDED
(Sep 1, 2026)
PHASE1, PHASE2 Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma Northwestern University NA
RECRUITING
(Sep 1, 2026)
PHASE1 Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors Milton S. Hershey Medical Center NA
RECRUITING
(Sep 1, 2026)
PHASE1, PHASE2 PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and Ependymoma Washington University School of Medicine NA
SUSPENDED
(Sep 1, 2026)
PHASE1, PHASE2 Trial of Glioblastoma Immunotherapy Advancement With Nivolumab and Relatlimab Duke University NA
RECRUITING
(Sep 1, 2026)
PHASE2 Study of ABBV-637 or ABBV-155 With ERAS-801 for People With Glioblastoma Memorial Sloan Kettering Cancer Center NA
RECRUITING
(Sep 1, 2026)
PHASE1 IGNITE: Study of Tirabrutinib vs Rituximab/Temozolomide for Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL) Ono Pharmaceutical Co., Ltd. NA
RECRUITING
(Sep 1, 2026)
PHASE3 Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer Alliance for Clinical Trials in Oncology NA
RECRUITING
(Sep 1, 2026)
PHASE3 Comparison of Cerebraca Wafer Plus Temozolomide Versus Temozolomide Alone in Recurrent Glioblastoma Everfront Biotech Co., Ltd. NA
NOT YET RECRUITING
(Sep 1, 2026)
PHASE2, PHASE3 Combination ADI-PEG 20, TMZ, and RT for Treatment of Newly Diagnosed High-grade Glioma (HGG) Sabine Mueller, MD, PhD NA
NOT YET RECRUITING
(Sep 1, 2026)
PHASE1, PHASE2 Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma NRG Oncology NA
RECRUITING
(Sep 1, 2026)
PHASE3 A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5) Bristol-Myers Squibb NA
RECRUITING
(Sep 1, 2026)
PHASE2 Temozolomide, With or Without WSD0922-FU, for the Treatment of EGFR-Mutant, IDH-Wildtype Glioblastoma Mayo Clinic NA
SUSPENDED
(Sep 1, 2026)
PHASE2 Trial of Temozolomide in BAP1 Mutated Patients With Advanced or Metastatic Cutaneous Melanoma Assistance Publique Hopitaux De Marseille NA
NOT YET RECRUITING
(Sep 1, 2026)
PHASE2 Vorinostat and Temozolomide in Treating Patients With Malignant Gliomas National Cancer Institute (NCI) NA
ACTIVE NOT RECRUITING
(Aug 1, 2026)
PHASE1 Bevacizumab Alone Versus Dose-dense Temozolomide Followed by Bevacizumab for Recurrent Glioblastoma, Phase III Kyorin University NA
COMPLETED
(Aug 1, 2026)
PHASE3 Pembrolizumab and Standard Therapy in Treating Patients With Glioblastoma Mayo Clinic NA
ACTIVE NOT RECRUITING
(Aug 1, 2026)
PHASE2 Nivolumab and Temozolomide in Treating Patients With Recurrent or Refractory Small-Cell Lung Cancer or Advanced Neuroendocrine Cancer Dwight Owen NA
COMPLETED
(Aug 1, 2026)
PHASE2 A Study of NanO2™ Combined With Radiation and Temozolomide in Patients With Newly Diagnosed GBM NuvOx LLC NA
ACTIVE NOT RECRUITING
(Aug 1, 2026)
PHASE2 BRiTE - Bispecific T Cell Engager for Patients With Glioblastoma Mustafa Khasraw, MBChB, MD, FRCP, FRACP NA
RECRUITING
(Aug 1, 2026)
PHASE1 Preoperative Radiosurgery for the Treatment of High Grade Glioma, NeoGlioma Trial Mayo Clinic NA
RECRUITING
(Aug 1, 2026)
PHASE1 PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma Nationwide Children's Hospital NA
RECRUITING
(Aug 1, 2026)
PHASE2 SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance) Nuvation Bio Inc. NA
RECRUITING
(Aug 1, 2026)
PHASE3 Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies AstraZeneca NA
RECRUITING
(Aug 1, 2026)
PHASE1, PHASE2 To Evaluate the Efficacy and Safety of Naxitamab in Patients With Refractory Ewing's Sarcoma (Butterfly) Anna Raciborska NA
RECRUITING
(Aug 1, 2026)
PHASE2 Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) for the Treatment of Patients With Progressing Metastatic Neuroendocrine Carcinomas Roswell Park Cancer Institute NA
SUSPENDED
(Aug 1, 2026)
PHASE2 Glioma Adaptive Radiotherapy With Development of an Artificial Intelligence Workflow Tata Memorial Centre NA
RECRUITING
(Aug 1, 2026)
PHASE2 A Phase II Study With a Safety Run-In of the Addition of N-803 to a Chemoimmunotherapy Backbone for the Treatment of Patients With Relapsed or Refractory Neuroblastoma St. Jude Children's Research Hospital NA
RECRUITING
(Aug 1, 2026)
PHASE2 Liothyronine in Combination With BIT Regimen for Medulloblastoma With or Without Minimal Residual Disease Sabine Mueller, MD, PhD NA
RECRUITING
(Aug 1, 2026)
PHASE1, PHASE2 Adebrelimab Plus Temozolomide ± Hyperbaric Oxygen for Primary Glioblastoma Wei Jiang NA
NOT YET RECRUITING
(Aug 1, 2026)
PHASE2 SurVaxM Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Roswell Park Cancer Institute NA
ACTIVE NOT RECRUITING
(Jul 1, 2026)
PHASE2 Safety and Efficacy Study in Recurrent or Progressive Grade III or IV IDH1 Mutated Glioma Neonc Technologies, Inc. NA
ACTIVE NOT RECRUITING
(Jul 1, 2026)
PHASE1, PHASE2 Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma NRG Oncology NA
ACTIVE NOT RECRUITING
(Jul 1, 2026)
PHASE2 Temozolomide (TMZ) In Advanced Succinate Dehydrogenase (SDH)-Mutant/Deficient Gastrointestinal Stromal Tumor (GIST) Adam Burgoyne, MD, PhD NA
COMPLETED
(Jul 1, 2026)
PHASE2 Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors Valent Technologies, LLC NA
ACTIVE NOT RECRUITING
(Jul 1, 2026)
PHASE1 A Phase 2b Clinical Study With a Combination Immunotherapy in Newly Diagnosed Patients With Glioblastoma Imvax NA
ACTIVE NOT RECRUITING
(Jul 1, 2026)
PHASE2 Phase I Trial of DNA-PK Inhibitor (PEPOSERTIB ) in Combination With Radiation and Adjuvant Temozolomide in Newly Diagnosed MGMT Unmethylated and Recurrent Glioblastoma M.D. Anderson Cancer Center NA
ACTIVE NOT RECRUITING
(Jul 1, 2026)
PHASE1 Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas M.D. Anderson Cancer Center NA
RECRUITING
(Jul 1, 2026)
PHASE2 Short Course Radiotherapy for the Treatment of Patients With Glioblastoma, SAGA Study Mayo Clinic NA
ACTIVE NOT RECRUITING
(Jul 1, 2026)
PHASE2 An Open, Single-center Clinical Study of Surufatinib Combined With Temozolomide and S-1 in the First-line Treatment of Advanced Neuroendocrine Tumors Cancer Institute and Hospital, Chinese Academy of Medical Sciences NA
RECRUITING
(Jul 1, 2026)
PHASE1, PHASE2 PH Weighted Chemical Exchange Saturation Transfer MRI-Based Surgical Resection to Improve Survival in Patients With Glioblastoma Jonsson Comprehensive Cancer Center NA
NOT YET RECRUITING
(Jul 1, 2026)
PHASE3 Vorasidenib in Combination With Temozolomide (TMZ) in IDH-mutant Glioma Institut de Recherches Internationales Servier NA
ACTIVE NOT RECRUITING
(Jul 1, 2026)
PHASE1, PHASE2 PEEL-224, Vincristine and Temozolomide in Pediatric Solid Tumors Theodore Laetsch NA
RECRUITING
(Jul 1, 2026)
PHASE1, PHASE2 Study of NMS-03305293 in Adult Patient With Relapsed Small Cell Lung Cancer Nerviano Medical Sciences NA
RECRUITING
(Jul 1, 2026)
PHASE1 CART-EGFR-IL13Ra2 in Newly Diagnosed GBM Following Initial Radiotherapy University of Pennsylvania NA
ACTIVE NOT RECRUITING
(Jul 1, 2026)
PHASE1 Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma Baptist Health South Florida NA
RECRUITING
(Jul 1, 2026)
PHASE2 Feasibility Study of Prolonged Administration of Naxitamab, Irinotecan, and Temozolomide for Patients With Relapsed or Refractory Neuroblastoma Steven DuBois, MD NA
RECRUITING
(Jul 1, 2026)
PHASE1 Adjuvant Temozolomide ± 5-Aminolevulinic Acid + Low Intensity Diffuse Ultrasound Sonodynamic Therapy System for Newly Diagnosed Glioblastoma Alpheus Medical, Inc. NA
RECRUITING
(Jul 1, 2026)
PHASE2 Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG). BrainChild Bio, Inc NA
RECRUITING
(Jul 1, 2026)
PHASE2 Nimotuzumab Combined With the Stupp Regimen for Postoperative Residual Glioblastoma Tianjin First Central Hospital NA
NOT YET RECRUITING
(Jul 1, 2026)
PHASE2 Preoperative Proton Irradiation for High-grade Brain Gliomas. National Medical Research Radiological Centre of the Ministry of Health of Russia NA
RECRUITING
(Jul 1, 2026)
PHASE1 Survivin-Targeted Dendritic Cell (DC) Cell Injection for Newly Diagnosed Glioblastoma Beijing Tricision Biotherapeutics Inc NA
NOT YET RECRUITING
(Jul 1, 2026)
PHASE2 Trial of NLG802 Indoximod Prodrug Plus Temozolomide for Patients With Progressive Pediatric Brain Cancer Lumos Pharma NA
NOT YET RECRUITING
(Jul 1, 2026)
PHASE1 Phase II Study Incorporating Pegylated Interferon In the Treatment For Children With High-Risk Melanoma St. Jude Children's Research Hospital NA
ACTIVE NOT RECRUITING
(Jun 1, 2026)
PHASE2 Subventricular Zone (SVZ) and Temozolomide in Glioblastoma Multiforme Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins NA
ACTIVE NOT RECRUITING
(Jun 1, 2026)
PHASE2 Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma NRG Oncology NA
ACTIVE NOT RECRUITING
(Jun 1, 2026)
PHASE2 Adjuvant Dendritic Cell-immunotherapy Plus Temozolomide in Glioblastoma Patients University Hospital, Antwerp NA
ACTIVE NOT RECRUITING
(Jun 1, 2026)
PHASE1, PHASE2 PEP-CMV in Recurrent MEdulloblastoma/Malignant Glioma Daniel Landi NA
ACTIVE NOT RECRUITING
(Jun 1, 2026)
PHASE1 Ruxolitinib With Radiation and Temozolomide for Grade III Gliomas and Glioblastoma Case Comprehensive Cancer Center NA
COMPLETED
(Jun 1, 2026)
PHASE1 Hyperpolarized Imaging in Diagnosing Participants With Glioma Susan Chang NA
RECRUITING
(Jun 1, 2026)
PHASE1 Adjuvant Dendritic Cell Immunotherapy for Pediatric Patients With High-grade Glioma or Diffuse Intrinsic Pontine Glioma University Hospital, Antwerp NA
COMPLETED
(Jun 1, 2026)
PHASE1, PHASE2 Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness National Cancer Institute (NCI) NA
RECRUITING
(Jun 1, 2026)
PHASE1, PHASE2 New Adjuvant Vaccine in Glioblastoma, a Phase 1/2a Study Assistance Publique - Hôpitaux de Paris NA
RECRUITING
(Jun 1, 2026)
PHASE1, PHASE2 A Study of 177Lu-PSMA-617 in People With Gliomas Memorial Sloan Kettering Cancer Center NA
RECRUITING
(Jun 1, 2026)
PHASE1 SM-1 Combined With Temozolomide in Subjects With Refractory or Recurrent High-Grade Gliomas Shenzhen Zhenxing Medical Technology Co., Ltd NA
COMPLETED
(Jun 1, 2026)
PHASE1 INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM) Inovio Pharmaceuticals NA
ACTIVE NOT RECRUITING
(May 1, 2026)
PHASE1, PHASE2 DC Migration Study to Evaluate TReg Depletion In GBM Patients With and Without Varlilumab Annick Desjardins, MD NA
ACTIVE NOT RECRUITING
(May 1, 2026)
PHASE2 VITAS: Atezolizumab in Combination With Chemotherapy for Pediatric Relapsed/Refractory Solid Tumors University of Texas Southwestern Medical Center NA
RECRUITING
(May 1, 2026)
PHASE1, PHASE2 Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma St. Jude Children's Research Hospital NA
RECRUITING
(May 1, 2026)
PHASE1, PHASE2 A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma Children's Oncology Group NA
ACTIVE NOT RECRUITING
(May 1, 2026)
PHASE1 Dose Finding Study of [177Lu]Lu-NeoB in Newly Diagnosed Glioblastoma and in Recurrent Glioblastoma Novartis Pharmaceuticals NA
ACTIVE NOT RECRUITING
(May 1, 2026)
PHASE1 A Phase Ib Trial of Eribulin in Combination With Irinotecan and Temozolamide in Children With Relapsed or Refractory Solid Tumors M.D. Anderson Cancer Center NA
RECRUITING
(May 1, 2026)
PHASE1 Combination of Tarlatamab and Temozolomide in Patients With Central Nervous System Tumors Centre Leon Berard NA
RECRUITING
(May 1, 2026)
PHASE1, PHASE2 Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII Black Diamond Therapeutics, Inc. NA
RECRUITING
(May 1, 2026)
PHASE2 A Phase I First-in-human Trial of Bvax (B-cell Vaccination) in Addition to Standard of Care Chemoradiotherapy for Newly Diagnosed Glioblastoma Catalina Lee Chang NA
NOT YET RECRUITING
(May 1, 2026)
PHASE1 A Rollover Study of NBM-BMX in Combination With Temozolomide in Patients With Newly Diagnosed Glioblastoma Novelwise Pharmaceutical Corporation NA
RECRUITING
(May 1, 2026)
PHASE1, PHASE2 A Phase 1/2 Study of Safety and Tolerability of MT-125 With Chemoradiation in Patients With Newly Diagnosed MGMT Methylated Glioblastoma Myosin Therapeutics Inc. NA
NOT YET RECRUITING
(May 1, 2026)
PHASE1, PHASE2 FG001 Near-Infrared Fluorescence Imaging During Tumor Resection in Newly Diagnosed High-Grade Glioma FluoGuide A/S NA
NOT YET RECRUITING
(May 1, 2026)
PHASE2 Association of Peripheral Blood Immunologic Response to Therapeutic Response to Adjuvant Treatment With Immune Checkpoint Inhibition (ICI) in Patients With Newly Diagnosed Glioblastoma or Gliosarcoma National Cancer Institute (NCI) NA
COMPLETED
(Apr 15, 2026)
PHASE2 Phase III Study Comparing 2 Brain Conformational Radiotherapy in Combination With Chemotherapy in the Treatment of Glioblastoma Institut Claudius Regaud NA
TERMINATED
(Apr 1, 2026)
PHASE3 Temozolomide With or Without Veliparib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme National Cancer Institute (NCI) NA
ACTIVE NOT RECRUITING
(Apr 1, 2026)
PHASE2, PHASE3 Personalized NeoAntigen Cancer Vaccine w RT Plus Pembrolizumab for Patients With Newly Diagnosed GBM Dana-Farber Cancer Institute NA
ACTIVE NOT RECRUITING
(Apr 1, 2026)
PHASE1 Ketogenic Diet in Combination With Standard-of-care Radiation and Temozolomide for Patients With Glioblastoma Jethro Hu NA
COMPLETED
(Apr 1, 2026)
PHASE1 Cabozantinib and Temozolomide for the Treatment of Unresectable or Metastatic Leiomyosarcoma or Other Soft Tissue Sarcoma City of Hope Medical Center NA
ACTIVE NOT RECRUITING
(Apr 1, 2026)
PHASE2 Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma National Cancer Institute (NCI) NA
COMPLETED
(Apr 1, 2026)
PHASE2, PHASE3 Temozolomide and Atezolizumab for Subsequent Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer Dwight Owen NA
RECRUITING
(Apr 1, 2026)
PHASE2 Radiation/Temozolomide and Immunotherapy With Daratumumab to Improve Antitumor Efficacy in Glioblastoma West Virginia University NA
ACTIVE NOT RECRUITING
(Apr 1, 2026)
PHASE1, PHASE2 Safety & Efficacy of DC Vaccine and TMZ for the Treatment of Newly-diagnosed Glioblastoma After Surgery Beijing Tiantan Hospital NA
COMPLETED
(Apr 1, 2026)
PHASE1 ETAPA I: Peptide-based Tumor Associated Antigen Vaccine in GBM Mustafa Khasraw, MBChB, MD, FRCP, FRACP NA
ACTIVE NOT RECRUITING
(Apr 1, 2026)
PHASE1 UNITy-BasED MR-Linac Adaptive Simultaneous Integrated Hypofractionated Boost Trial for High Grade Glioma in the Elderly Sunnybrook Health Sciences Centre NA
ACTIVE NOT RECRUITING
(Apr 1, 2026)
PHASE2 Natural Killer Cell Therapy (UD TGFbetai NK Cells) and Temozolomide for the Treatment of Stage IV Melanoma Metastatic to the Brain Kari Kendra NA
RECRUITING
(Apr 1, 2026)
PHASE1, PHASE2 ARISTOCRAT: Blinded Trial of Temozolomide +/- Cannabinoids University of Birmingham NA
RECRUITING
(Apr 1, 2026)
PHASE2 The Efficacy and Safety of Temozolomide in SDH-deficient GIST Asan Medical Center NA
RECRUITING
(Apr 1, 2026)
PHASE2 NBM-BMX Administered Orally to Patients With Solid Tumors or Newly Diagnosed Glioblastoma Novelwise Pharmaceutical Corporation NA
RECRUITING
(Apr 1, 2026)
PHASE1, PHASE2 PH Sensitive MRI Based Resections of Glioblastoma University of California, Los Angeles NA
RECRUITING
(Apr 1, 2026)
PHASE1 A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients NaviFUS Corporation NA
RECRUITING
(Apr 1, 2026)
PHASE3 G-CSF After Chemo-radiation in Patients With Glioblastoma Massachusetts General Hospital NA
RECRUITING
(Apr 1, 2026)
PHASE2 DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM) Diakonos Oncology Corporation NA
RECRUITING
(Apr 1, 2026)
PHASE2 A Phase 1/2 Study of the Safety and Tolerability of MT-125 in GBM Patients Myosin Therapeutics Inc. NA
RECRUITING
(Apr 1, 2026)
PHASE1, PHASE2 A Clinical Trial Testing the Safety of the Investigational Drug Pumitamig (BNT327) and How Well it Works in Patients With Recurrent Glioblastoma BioNTech SE NA
RECRUITING
(Apr 1, 2026)
PHASE2 Focused Ultrasound Blood-Brain Barrier Opening in Pontine Diffuse Midline Glioma to Enhance Temozolomide Therapy: Pilot Feasibility Study (FIDES) UMC Utrecht NA
NOT YET RECRUITING
(Apr 1, 2026)
PHASE1, PHASE2 A Prospective, Single-arm Clinical Study on the Safety and Efficacy of Ivoximab Combined With Temozolomide in the Treatment of Relapsed/Refractory Glioma The First Affiliated Hospital of Zhengzhou University NA
RECRUITING
(Apr 1, 2026)
PHASE1, PHASE2 Temozolomide With or Without Veliparib in Treating Patients With Relapsed or Refractory Small Cell Lung Cancer National Cancer Institute (NCI) NA
ACTIVE NOT RECRUITING
(Mar 1, 2026)
PHASE2 BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomas University of California, San Francisco NA
ACTIVE NOT RECRUITING
(Mar 1, 2026)
PHASE1 Multiparametric MR-Guided High Dose Adaptive Radiotherapy With Concurrent Temozolomide in Patients With Newly Diagnosed Glioblastoma University of Michigan Rogel Cancer Center NA
ACTIVE NOT RECRUITING
(Mar 1, 2026)
PHASE2 DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma University of California, San Francisco NA
RECRUITING
(Mar 1, 2026)
PHASE1, PHASE2 Integrating Biology for Safe Intensification of Glioblastoma Hypofractionated Treatment on the MR-Linac NYU Langone Health NA
NOT YET RECRUITING
(Mar 1, 2026)
PHASE1 Neoadjuvant Pucotenlimab Combined With Lenvatinib and Temozolomide in Resectable Stage IIB/III Acral Melanoma Shanghai Zhongshan Hospital NA
NOT YET RECRUITING
(Mar 1, 2026)
PHASE2