Temozolomide Patent Expiration

Temozolomide is Used for treating malignant neoplasms. It was first introduced by Merck Sharp And Dohme Corp in its drug Temodar on Aug 11, 1999. 18 different companies have introduced drugs containing Temozolomide.


Temozolomide Patents

Given below is the list of patents protecting Temozolomide, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Temodar US6987108 Pharmaceutical formulations of antineoplastic agents and processes of making and using the same Sep 08, 2023

(Expired)

Merck Sharp Dohme
Temodar US7786118 Pharmaceutical formulations of antineoplastic agents Feb 21, 2023

(Expired)

Merck Sharp Dohme
Temodar US8623868 Processes of making and using pharmaceutical formulations of antineoplastic agents Feb 21, 2023

(Expired)

Merck Sharp Dohme
Temodar US5260291

(Pediatric)

Tetrazine derivatives Feb 11, 2014

(Expired)

Merck Sharp Dohme
Temodar US5260291 Tetrazine derivatives Aug 11, 2013

(Expired)

Merck Sharp Dohme



A patent's expiry date may change depending upon legal activities going on that patent. Critical activities like abandoning of a patent, term extension of a patent or amendment of its claims can increase or decrease the life of a patent hence affecting its expiry date and in turn affecting the generic launch date of that drug. Tracking these ongoing activities on a patent application helps to keep an eye on the latest developments in the patent process of the drug which can give an idea of how early a drug's generic could be available. The next section provides a list of recent legal activities on Temozolomide's patents.

Given below is the list recent legal activities going on the following patents of Temozolomide.

Activity Date Patent Number
Patent litigations
Payment of Maintenance Fee, 12th Year, Large Entity 13 Jan, 2022 US7786118
Payment of Maintenance Fee, 8th Year, Large Entity 17 Jan, 2018 US7786118
Correspondence Address Change 26 Aug, 2011 US7786118
Correspondence Address Change 26 Aug, 2011 US6987108
Post Issue Communication - Certificate of Correction 09 Feb, 2011 US7786118
Recordation of Patent Grant Mailed 31 Aug, 2010 US7786118
Patent Issue Date Used in PTA Calculation 31 Aug, 2010 US7786118
Issue Notification Mailed 11 Aug, 2010 US7786118
Application Is Considered Ready for Issue 03 Aug, 2010 US7786118
Dispatch to FDC 03 Aug, 2010 US7786118


Temozolomide's Family Patents

Family Patents

Explore Our Curated Drug Screens

Drugs Generating Over $1 Billion in Annual Revenue
Explore the top-performing drugs that dominate the pharmaceutical industry
View List
NCE-1 Patent Expiry in the Next 1 Year
Identify opportunities as new chemical entity (NCE-1) patents approach expiry
View List
Recently Granted Patents in EP
Find the opportunity to file Oppositions
View List

Temozolomide Generic API Manufacturers

Several generic applications have been filed for Temozolomide. The first generic version for Temozolomide was by Heritage Pharma Labs Inc Dba Avet Pharma Labs Inc and was approved on Mar 1, 2010. And the latest generic version is by Hetero Labs Ltd Unit V and was approved on Aug 23, 2024.

Given below is the list of companies who have filed for Temozolomide generic, along with the locations of their manufacturing plants worldwide.