Tapentadol Hydrochloride Patent Expiration

Tapentadol Hydrochloride is Used for managing severe chronic pain, including neuropathic pain associated with diabetic peripheral neuropathy, when other treatment options are inadequate. It was first introduced by Collegium Pharmaceutical Inc in its drug Nucynta on Nov 20, 2008. Another drug containing Tapentadol Hydrochloride is Nucynta Er.


Tapentadol Hydrochloride Patents

Given below is the list of patents protecting Tapentadol Hydrochloride, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Nucynta US6071970 Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases Jun 06, 2017

(Expired)

Collegium Pharm Inc
Nucynta US7994364 Crystalline forms of (−)-(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)-phenol hydrochloride Jun 27, 2025 Collegium Pharm Inc
Nucynta USRE39593 1-phenyl-3-dimethylaminopropane compounds with a pharmacological effects Aug 05, 2022

(Expired)

Collegium Pharm Inc
Nucynta Er US11007156 Prolonged release pharmaceutical composition containing 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol Oct 22, 2022

(Expired)

Collegium Pharm Inc
Nucynta Er US11344512 Titration of tapentadol Apr 21, 2028 Collegium Pharm Inc
Nucynta Er US6071970 Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases Jun 06, 2017

(Expired)

Collegium Pharm Inc
Nucynta Er US7994364 Crystalline forms of (−)-(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)-phenol hydrochloride Jun 27, 2025 Collegium Pharm Inc
Nucynta Er US8075872 Abuse-proofed dosage form Nov 20, 2023

(Expired)

Collegium Pharm Inc
Nucynta Er US8114383 Abuse-proofed dosage form Oct 10, 2024 Collegium Pharm Inc
Nucynta Er US8309060 Abuse-proofed dosage form Nov 20, 2023

(Expired)

Collegium Pharm Inc
Nucynta Er US8420056 Abuse-proofed dosage form Nov 20, 2023

(Expired)

Collegium Pharm Inc
Nucynta Er US8536130 Use of 1 phenyl-3-dimethylamino-propane compounds for treating neuropathic pain Sep 22, 2028 Collegium Pharm Inc
Nucynta Er USRE39593 1-phenyl-3-dimethylaminopropane compounds with a pharmacological effects Aug 05, 2022

(Expired)

Collegium Pharm Inc


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