Spironolactone Patent Expiration

Spironolactone is Used for managing edema in cirrhotic patients and treating heart failure with reduced ejection fraction to increase survival and reduce hospitalizations. It was first introduced by Pfizer Inc in its drug Aldactone on Dec 30, 1982. Another drug containing Spironolactone is Carospir. 27 different companies have introduced drugs containing Spironolactone.


Spironolactone Patents

Given below is the list of patents protecting Spironolactone, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Carospir US10493083 Spironolactone aqueous compositions Oct 28, 2036 Cmp Dev Llc
Carospir US10624906 Spironolactone aqueous compositions Oct 28, 2036 Cmp Dev Llc
Carospir US10660907 Spironolactone aqueous compositions Oct 28, 2036 Cmp Dev Llc
Carospir US10888570 Spironolactone aqueous compositions Oct 28, 2036 Cmp Dev Llc
Carospir US11389461 Spironolactone aqueous compositions Oct 28, 2036 Cmp Dev Llc
Carospir US11395828 Spironolactone aqueous compositions Oct 28, 2036 Cmp Dev Llc
Carospir US11491166 Spironolactone aqueous compositions Oct 28, 2036 Cmp Dev Llc
Carospir US9757394 Spironolactone aqueous formulations Oct 28, 2036 Cmp Dev Llc



Spironolactone's Family Patents

Family Patents

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Spironolactone Generic API Manufacturers

Several generic applications have been filed for Spironolactone. The first generic version for Spironolactone was by Ivax Pharmaceuticals Inc and was approved on Approved Prior to Jan 1, 1982. And the latest generic version is by Annora Pharma Private Ltd and was approved on Jul 25, 2025.

Given below is the list of companies who have filed for Spironolactone generic, along with the locations of their manufacturing plants worldwide.