Semaglutide Patent Expiration

Semaglutide is used for treating Type 2 diabetes as an adjunct to diet and exercise to improve glycemic control in adults. It was first introduced by Novo Nordisk Inc in its drug Ozempic on Dec 5, 2017. Other drugs containing Semaglutide are Wegovy Hd, Wegovy, Wegovy Flextouch, Rybelsus.


Semaglutide Patents

Given below is the list of patents protecting Semaglutide, along with the drug name that holds that patent and the company name owning that drug.

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Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Ozempic US11318191 GLP-1 compositions and uses thereof Feb 17, 2041 Novo
Wegovy US11318191 GLP-1 compositions and uses thereof Feb 17, 2041 Novo
Wegovy Hd US11318191 GLP-1 compositions and uses thereof Feb 17, 2041 Novo
Wegovy US11478533 Semaglutide For Use In Medicine May 13, 2040 Novo
Wegovy Flextouch US11478533 Semaglutide For Use In Medicine May 13, 2040 Novo
Ozempic US11833248 Solid compositions comprising a GLP-1 agonist and a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid Feb 01, 2039 Novo
Ozempic US12396953 Solid Compositions Comprising A Glp-1 Agonist And A Salt Of N-(8-(2-Hydroxybenzoyl)Amino)Caprylic Acid Feb 01, 2039 Novo
Wegovy US11833248 Solid compositions comprising a GLP-1 agonist and a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid Feb 01, 2039 Novo
Wegovy US12396953 Solid Compositions Comprising A Glp-1 Agonist And A Salt Of N-(8-(2-Hydroxybenzoyl)Amino)Caprylic Acid Feb 01, 2039 Novo
Ozempic US12295988 Semaglutide in medical therapy Oct 10, 2038 Novo
Wegovy US12029779 Semaglutide in medical therapy Oct 10, 2038 Novo
Wegovy US12551536 Semaglutide In Medical Therapy Oct 10, 2038 Novo
Wegovy Flextouch US12029779 Semaglutide in medical therapy Oct 10, 2038 Novo
Wegovy Flextouch US12551536 Semaglutide In Medical Therapy Oct 10, 2038 Novo
Wegovy Hd US12029779 Semaglutide in medical therapy Oct 10, 2038 Novo
Wegovy Hd US12551536 Semaglutide In Medical Therapy Oct 10, 2038 Novo
Ozempic US10888605 GLP-1 compositions and uses thereof Aug 24, 2038 Novo
Ozempic US11752198 GLP-1 compositions and uses thereof Aug 24, 2038 Novo
Ozempic US12214017 GLP-1 compositions and uses thereof Aug 24, 2038 Novo
Wegovy US10888605 GLP-1 compositions and uses thereof Aug 24, 2038 Novo
Wegovy US11752198 GLP-1 compositions and uses thereof Aug 24, 2038 Novo
Wegovy US12214017 GLP-1 compositions and uses thereof Aug 24, 2038 Novo
Wegovy Hd US10888605 GLP-1 compositions and uses thereof Aug 24, 2038 Novo
Wegovy Hd US11752198 GLP-1 compositions and uses thereof Aug 24, 2038 Novo
Wegovy Hd US12214017 GLP-1 compositions and uses thereof Aug 24, 2038 Novo
Ozempic US12569543 Semaglutide In Cardiovascular Conditions Apr 28, 2037 Novo
Wegovy US12569543 Semaglutide In Cardiovascular Conditions Apr 28, 2037 Novo
Wegovy US12569543 Apr 28, 2037 Novo
Wegovy Hd US12569543 Apr 28, 2037 Novo
Ozempic US10278923 Oral dosing of GLP-1 compounds May 02, 2034 Novo
Ozempic US12239739 Oral dosing of GLP-1 compounds May 02, 2034 Novo
Ozempic US12514822 Oral Dosing Of Glp-1 Compounds May 02, 2034 Novo
Rybelsus US10278923 Oral dosing of GLP-1 compounds May 02, 2034 Novo
Rybelsus US12239739 Oral dosing of GLP-1 compounds May 02, 2034 Novo
Rybelsus US12514822 Oral Dosing Of Glp-1 Compounds May 02, 2034 Novo
Wegovy US10278923 Oral dosing of GLP-1 compounds May 02, 2034 Novo
Wegovy US12239739 Oral dosing of GLP-1 compounds May 02, 2034 Novo
Ozempic US10335462 Use of long-acting GLP-1 peptides Jun 21, 2033 Novo
Wegovy US9764003 Use of long-acting GLP-1 peptides Jun 21, 2033 Novo
Wegovy Flextouch US9764003 Use of long-acting GLP-1 peptides Jun 21, 2033 Novo
Wegovy Hd US9764003 Use of long-acting GLP-1 peptides Jun 21, 2033 Novo
Ozempic US11033499 Tablet Formulation Comprising A Glp-1 Peptide And A Delivery Agent Jun 19, 2033 Novo
Rybelsus US11033499 Tablet Formulation Comprising A Glp-1 Peptide And A Delivery Agent Jun 19, 2033 Novo
Wegovy US11033499 Tablet Formulation Comprising A Glp-1 Peptide And A Delivery Agent Jun 19, 2033 Novo
Rybelsus US10933120 Compositions of GLP-1 peptides and preparation thereof Mar 15, 2033 Novo
Rybelsus US11759501 Compositions of GLP-1 peptides and preparation thereof Mar 15, 2033 Novo
Rybelsus US11759502 Compositions of GLP-1 peptides and preparation thereof Mar 15, 2033 Novo
Rybelsus US11759503 Compositions of GLP-1 peptides and preparation thereof Mar 15, 2033 Novo
Rybelsus US12594326 Compositions Of Glp-1 Peptides And Preparation Thereof Mar 15, 2033 Novo
Ozempic US9132239 Dial-down mechanism for wind-up pen Feb 01, 2032 Novo
Ozempic US11382957 Solid compositions comprising a GLP-1 agonist and a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid Dec 16, 2031 Novo
Ozempic US9278123 Solid compositions comprising a GLP-1 agonist and a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid Dec 16, 2031 Novo
Rybelsus US10086047 Solid compositions comprising a GLP-1 agonist and a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid Dec 16, 2031 Novo
Rybelsus US10960052 Solid compositions comprising a GLP-1 agonist and a salt of N-(8-(2-hydroxybenzoyl) amino) caprylic acid Dec 16, 2031 Novo
Rybelsus US11382957 Solid compositions comprising a GLP-1 agonist and a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid Dec 16, 2031 Novo
Rybelsus US9278123 Solid compositions comprising a GLP-1 agonist and a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid Dec 16, 2031 Novo
Wegovy US11382957 Solid compositions comprising a GLP-1 agonist and a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid Dec 16, 2031 Novo
Wegovy US9278123 Solid compositions comprising a GLP-1 agonist and a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid Dec 16, 2031 Novo
Ozempic US8129343 Acylated GLP-1 compounds Dec 05, 2031 Novo
Rybelsus US8129343 Acylated GLP-1 compounds Dec 05, 2031 Novo
Wegovy US8129343 Acylated GLP-1 compounds Dec 05, 2031 Novo
Wegovy Flextouch US8129343 Acylated GLP-1 compounds Dec 05, 2031 Novo
Wegovy Hd US8129343 Acylated GLP-1 compounds Dec 05, 2031 Novo
Ozempic US9457154 Injection device with an end of dose feedback mechanism Sep 29, 2027 Novo
Ozempic US9687611 Injection device with torsion spring and rotatable display Feb 27, 2027 Novo
Ozempic USRE46363 Dial-down mechanism for wind-up pen Aug 03, 2026

(Expired)

Novo
Ozempic US10220155 Syringe device with a dose limiting mechanism and an additional safety mechanism Jul 17, 2026

(Expired)

Novo
Ozempic US11097063 Syringe device with a dose limiting mechanism and an additional safety mechanism Jul 17, 2026

(Expired)

Novo
Ozempic US8920383 Dose mechanism for an injection device for limiting a dose setting corresponding to the amount of medicament left Jul 17, 2026

(Expired)

Novo
Ozempic US9775953 Dose mechanism for an injection device for limiting a dose setting corresponding to the amount of medicament left Jul 17, 2026

(Expired)

Novo
Ozempic US8536122 Acylated GLP-1 compounds Mar 20, 2026

(Expired)

Novo
Rybelsus US8536122 Acylated GLP-1 compounds Mar 20, 2026

(Expired)

Novo
Wegovy US8536122 Acylated GLP-1 compounds Mar 20, 2026

(Expired)

Novo
Ozempic US10357616 Injection device with an end of dose feedback mechanism Jan 20, 2026

(Expired)

Novo
Ozempic US10376652 Automatic injection device with a top release mechanism Jan 20, 2026

(Expired)

Novo
Ozempic US11311679 Automatic injection device with a top release mechanism Jan 20, 2026

(Expired)

Novo
Ozempic US9108002 Automatic injection device with a top release mechanism Jan 20, 2026

(Expired)

Novo
Ozempic US9616180 Automatic injection device with a top release mechanism Jan 20, 2026

(Expired)

Novo
Ozempic US9861757 Injection device with an end of dose feedback mechanism Jan 20, 2026

(Expired)

Novo
Ozempic US11446443 Injection device with torsion spring and rotatable display Oct 20, 2025

(Expired)

Novo
Ozempic US8684969 Injection device with torsion spring and rotatable display Oct 20, 2025

(Expired)

Novo
Ozempic US8114833 Propylene glycol-containing peptide formulations which are optimal for production and for use in injection devices Aug 13, 2025

(Expired)

Novo
Ozempic US7762994 Needle mounting system and a method for mounting a needle assembly May 23, 2024

(Expired)

Novo
Ozempic US8579869 Needle mounting system and a method for mounting a needle assembly Jun 30, 2023

(Expired)

Novo
Ozempic US6899699 Automatic injection device with reset feature Jan 02, 2022

(Expired)

Novo
Ozempic US8672898 Automatic injection device with reset feature Jan 02, 2022

(Expired)

Novo
Ozempic US9486588 Automatic injection device with reset feature Jan 02, 2022

(Expired)

Novo



A patent's expiry date may change depending upon legal activities going on that patent. Critical activities like abandoning of a patent, term extension of a patent or amendment of its claims can increase or decrease the life of a patent hence affecting its expiry date and in turn affecting the generic launch date of that drug. Tracking these ongoing activities on a patent application helps to keep an eye on the latest developments in the patent process of the drug which can give an idea of how early a drug's generic could be available. The next section provides a list of recent legal activities on Semaglutide's patents.

Given below is the list recent legal activities going on the following patents of Semaglutide.

Activity Date Patent Number
Patent litigations
Payment of Maintenance Fee, 4th Year, Large Entity 18 Dec, 2025 US11382957
Payment of Maintenance Fee, 4th Year, Large Entity 23 Oct, 2025 US11318191(Litigated)
Payment of Maintenance Fee, 8th Year, Large Entity 20 Feb, 2025 US9764003(Litigated)
Payment of Maintenance Fee, 4th Year, Large Entity 20 Aug, 2024 US10933120
Payment of Maintenance Fee, 4th Year, Large Entity 20 Aug, 2024 US10960052
Payment of Maintenance Fee, 4th Year, Large Entity 20 Jun, 2024 US10888605(Litigated)
Email Notification 20 Sep, 2023 US11759503
Email Notification 20 Sep, 2023 US11759501
Email Notification 20 Sep, 2023 US11759502
Patent eGrant Notification 19 Sep, 2023 US11759501


Semaglutide's Family Patents

Family Patents

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Clinical Trials

Recent Clinical Trials on Semaglutide:

Sometimes companies keep conducting clinical trials even after the drug's approval to discover new formulations, methods of use, or new treatment indications, so they could file for additional patents or receive regulatory exclusivity extensions, such as pediatric exclusivity, potentially delaying generic competition. Based on these recent clinical trials, generic companies need to consider the potential for new intellectual property or regulatory hurdles. These strategic moves by the drug owner might delay generic substitution or lead to additional sales of the brand drug, even after patent expiry. Semaglutide has 5 clinical trials that have been verified in 2024. Out of these 5, 1 trial is in PHASE4.

Title Lead Sponsor Collaborators Status Phases
Clinical Trials
A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes Novo Nordisk A/S NA ACTIVE NOT RECRUITING
(Sep 1, 2026)
PHASE3
Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH) Novo Nordisk A/S NA ACTIVE NOT RECRUITING
(Sep 1, 2026)
PHASE3
A Study in People With Obesity to Test the Effects of BI 456906 Compared With Semaglutide on Glucagon Receptor Activity in the Liver Boehringer Ingelheim NA ACTIVE NOT RECRUITING
(Sep 1, 2026)
PHASE1
Glucagon-Like Peptide-1 Receptor Agonist in the Treatment of Adult, Obesity-related, Symptomatic Asthma (GATA-3) Vanderbilt University Medical Center NA ACTIVE NOT RECRUITING
(Sep 1, 2026)
PHASE2
A Research Study on How Well Semaglutide Helps Children and Teenagers With Excess Body Weight Lose Weight Novo Nordisk A/S NA ACTIVE NOT RECRUITING
(Sep 1, 2026)
PHASE3
The Effect of Oral Semaglutide on Bone Turnover in Patients With T2D: a Randomized Placebo-controlled Clinical Trial Odense University Hospital NA ACTIVE NOT RECRUITING
(Sep 1, 2026)
PHASE2
A Research Study to See if Kidney Damage in People With Chronic Kidney Disease and Type 2 Diabetes Living With Overweight or Obesity Can be Reduced by CagriSema Compared to Semaglutide, Cagrilintide and Placebo Novo Nordisk A/S NA COMPLETED
(Sep 1, 2026)
PHASE2
Semaglutide for Post-Smoking Cessation Weight Management The University of Texas Health Science Center, Houston NA RECRUITING
(Sep 1, 2026)
PHASE2
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor Novo Nordisk A/S NA COMPLETED
(Sep 1, 2026)
PHASE3
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Once-daily Basal Insulin With or Without Metformin Novo Nordisk A/S NA COMPLETED
(Sep 1, 2026)
PHASE3
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or Both Novo Nordisk A/S NA COMPLETED
(Sep 1, 2026)
PHASE3
Evaluation Of Semaglutide in Adults With Cocaine Use Disorder With and Without HIV University of Maryland, Baltimore NA ACTIVE NOT RECRUITING
(Sep 1, 2026)
PHASE2
A Research Study to Investigate the Effects of CagriSema Compared to Placebo in People With Type 2 Diabetes and Painful Diabetic Peripheral Neuropathy Novo Nordisk A/S NA COMPLETED
(Sep 1, 2026)
PHASE2
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide Eli Lilly and Company NA RECRUITING
(Sep 1, 2026)
PHASE2
Semaglutide for the Prevention Of Post-Transplant Diabetes Mellitus University Health Network, Toronto NA NOT YET RECRUITING
(Sep 1, 2026)
PHASE2, PHASE3
The Role of the Amylin Analogue Cagrilintide in Bone Metabolism Novo Nordisk A/S NA RECRUITING
(Sep 1, 2026)
PHASE1
A Study to See How Metabolism is Influenced by Weight Loss Due to Intervention With Cagrilintide and Semaglutide Compared to Diet Novo Nordisk A/S NA ACTIVE NOT RECRUITING
(Sep 1, 2026)
PHASE1
Study to Explore the Safety and Efficacy of NT-0796 as an Adjunct to Semaglutide in Participants With Obesity (RESOLVE-2) Rezera (formerly NodThera Limited) NA COMPLETED
(Sep 1, 2026)
PHASE2
Semaglutide (SEMA) for Alcohol Use Disorder (AUD) After Metabolic and Bariatric Surgery (MBS) Yale University NA ACTIVE NOT RECRUITING
(Sep 1, 2026)
PHASE1
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes Novo Nordisk A/S NA RECRUITING
(Sep 1, 2026)
PHASE3
A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes Novo Nordisk A/S NA RECRUITING
(Sep 1, 2026)
PHASE2
Proof-of-Concept Study Evaluating Total Body Weight, Physical Function & Safety of Enobosarm in Patients Treated With GLP-1 Receptor Agonist, for Weight Loss Veru Inc. NA ACTIVE NOT RECRUITING
(Sep 1, 2026)
PHASE2
A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With Obesity Novo Nordisk A/S NA ACTIVE NOT RECRUITING
(Sep 1, 2026)
PHASE2
Phase III Study of UBT251 Injection in Patients With Type 2 Diabetes With Inadequate Glycemic Control on Metformin ± Sulfonylurea/SGLT2 Inhibitor Therapy (UNIGUIDE-2) The United Bio-Technology (Hengqin) Co., Ltd. NA RECRUITING
(Sep 1, 2026)
PHASE3
A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes Novo Nordisk A/S NA RECRUITING
(Sep 1, 2026)
PHASE2
A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight Novo Nordisk A/S NA RECRUITING
(Sep 1, 2026)
PHASE3
Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body Weight Novo Nordisk A/S NA RECRUITING
(Sep 1, 2026)
PHASE3
Postpartum Semaglutide to Reduce Cardiometabolic Risk After Gestational Diabetes Mellitus University of Massachusetts, Worcester NA NOT YET RECRUITING
(Sep 1, 2026)
PHASE2, PHASE3
A Study Evaluating Safety and Tolerability of Switching From Semaglutide to Zovaglutide in Adults With Obesity (HORIZON-SWITCH-SZ) Beijing QL Biopharmaceutical Co.,Ltd NA NOT YET RECRUITING
(Sep 1, 2026)
PHASE2
Research Study on How People With Type 2 Diabetes Tolerate Switching From Semaglutide to Cagrisema Novo Nordisk A/S NA NOT YET RECRUITING
(Sep 1, 2026)
PHASE3
Comparative Study of Different Weekly GLP-1 Receptor Agonists Among Diabetic and Non-Diabetic Patients: Clinical Trial Zagazig University NA COMPLETED
(Sep 1, 2026)
PHASE3
Weekly GLP-1 Receptor Agonists in Obese Individuals Without Diabetes Zagazig University NA COMPLETED
(Sep 1, 2026)
PHASE3
A Study Comparing the Effects of BGM0504 Injection and Semaglutide Injection on Obese Subjects. Second Affiliated Hospital of Soochow University NA COMPLETED
(Sep 1, 2026)
PHASE2
Study to Assess the Effect and Safety of ALV-100 on Maintenance of Weight Loss Alveus Therapeutics, Inc. NA RECRUITING
(Sep 1, 2026)
PHASE2
Research Study to Investigate How Well Semaglutide Tablets Taken Once Daily Work in East Asian People Who Are Overweight or Living With Obesity Novo Nordisk A/S NA COMPLETED
(Aug 1, 2026)
PHASE3
A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose Weight Novo Nordisk A/S NA ACTIVE NOT RECRUITING
(Aug 1, 2026)
PHASE3
REDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood Vessels Novo Nordisk A/S NA ACTIVE NOT RECRUITING
(Aug 1, 2026)
PHASE3
A Research Study Looking at the Effect of Semaglutide on the Immune System and Other Biological Processes in People With Alzheimer's Disease Novo Nordisk A/S NA COMPLETED
(Aug 1, 2026)
PHASE3
A Study of Orforglipron (LY3502970) Compared With Semaglutide in Participants With Type 2 Diabetes Inadequately Controlled With Metformin Eli Lilly and Company NA COMPLETED
(Aug 1, 2026)
PHASE3
A Study to Test if Trevogrumab or Trevogrumab With Garetosmab When Taken With Semaglutide is Safe and How Well They Work in Adult Patients With Obesity for Weight Loss, Fat Loss, and Lean Mass Preservation Regeneron Pharmaceuticals NA ACTIVE NOT RECRUITING
(Aug 1, 2026)
PHASE2
A Research Study to Compare Blood Levels of Cagrilintide and Semaglutide After Single Doses of Different Versions of Injectable CagriSema in Adults With Overweight or Obesity Novo Nordisk A/S NA COMPLETED
(Aug 1, 2026)
PHASE1
Early Reinitiation of Semaglutide Post-Sleeve Gastrectomy in Youth Children's Hospital Los Angeles NA RECRUITING
(Aug 1, 2026)
PHASE3
A Study to See the Effect of NNC0194-0499 Alone or in Combination With Semaglutide on Blood Sugar Control in People Living With Type 1 Diabetes Novo Nordisk A/S NA ACTIVE NOT RECRUITING
(Aug 1, 2026)
PHASE1
A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight Novo Nordisk A/S NA RECRUITING
(Aug 1, 2026)
PHASE3
A Research Study to See if Two Different Formulations of Oral Semaglutide Are Equally Safe and Effective in Reducing the Blood Sugar Level in Japanese People With Type 2 Diabetes Novo Nordisk A/S NA COMPLETED
(Aug 1, 2026)
PHASE3
Efficacy and Safety of Ribupatide Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have Diabetes Kailera NA RECRUITING
(Aug 1, 2026)
PHASE3
A Study of CS060380 Tablets in Patients With MASH and Obesity Cascade Pharmaceuticals, Inc NA ACTIVE NOT RECRUITING
(Aug 1, 2026)
PHASE2
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight Novo Nordisk A/S NA RECRUITING
(Aug 1, 2026)
PHASE3
A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide Novo Nordisk A/S NA NOT YET RECRUITING
(Aug 1, 2026)
PHASE3
HMB Plus Vitamin D to Preserve Muscle in Older Adults Starting Semaglutide Vanderbilt University Medical Center NA NOT YET RECRUITING
(Aug 1, 2026)
PHASE2
A First-in-human Research Study on How NNC0721-8060 Works in People Living With Overweight or Obesity Novo Nordisk A/S NA RECRUITING
(Aug 1, 2026)
PHASE1
Semaglutide Dose Effects on Metabolic and Stress Hormone, Craving and Alcohol Use Outcomes Yale University NA NOT YET RECRUITING
(Aug 1, 2026)
PHASE1
Phase 2 Clinical Study of MWN109 Tablets in Participants With Type 2 Diabetes Mellitus Shanghai Minwei Biotechnology Co., Ltd NA RECRUITING
(Aug 1, 2026)
PHASE2
A Research Study to Compare a New Medicine Oral Semaglutide to a Dummy Medicine in Children and Teenagers With Type 2 Diabetes Novo Nordisk A/S NA COMPLETED
(Jul 1, 2026)
PHASE3
A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE) Novo Nordisk A/S NA COMPLETED
(Jul 1, 2026)
PHASE3
Pharmacogenetics of Response to GLP1R Agonists University of Maryland, Baltimore NA RECRUITING
(Jul 1, 2026)
PHASE1
Sit Less, Interact and Move More (SLIMM) 2 Study Srinvasan Beddhu NA RECRUITING
(Jul 1, 2026)
PHASE2
A Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor Novo Nordisk A/S NA COMPLETED
(Jul 1, 2026)
PHASE3
COMMETS- Combination MCI Metabolic Syndrome Rutgers, The State University of New Jersey NA RECRUITING
(Jul 1, 2026)
PHASE2
Obesity Complicating Type 1 Diabetes: GLP-1 Analogue Anti-obesity Treatment Yale University NA RECRUITING
(Jul 1, 2026)
PHASE2
Physiologic Response to Bariatric Surgery and the Impact of Adjunct Semaglutide in Adolescents University of Colorado, Denver NA RECRUITING
(Jul 1, 2026)
PHASE1
A Study of HRS9531 Versus Semaglutide Once Weekly as Add-on Therapy to Metformin Monotherapy or in Combination With SGLT2 Inhibitors in Participants With Type 2 Diabetes Fujian Shengdi Pharmaceutical Co., Ltd. NA COMPLETED
(Jul 1, 2026)
PHASE3
A Study to Evaluate the Effect of Retatrutide on Insulin Secretion and Insulin Sensitivity in Adult Participants With Type 2 Diabetes Mellitus Eli Lilly and Company NA ACTIVE NOT RECRUITING
(Jul 1, 2026)
PHASE1
A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-term Novo Nordisk A/S NA ACTIVE NOT RECRUITING
(Jul 1, 2026)
PHASE3
A Study to Compare Different Doses of RO7795081 With a Placebo or Semaglutide in People With Type 2 Diabetes Hoffmann-La Roche NA ACTIVE NOT RECRUITING
(Jul 1, 2026)
PHASE2
A Research Study to Compare Two Different Versions of Injectable CagriSema in People With Type 2 Diabetes Novo Nordisk A/S NA WITHDRAWN
(Jul 1, 2026)
PHASE2
A Research Study to Compare Different Versions of Injectable CagriSema and Placebo in People With Excess Body Weight Novo Nordisk A/S NA WITHDRAWN
(Jul 1, 2026)
PHASE3
A Phase 1 Clinical Trial to Assess the Safety of DWRX5003 and Relative Bioavailability to DWC202502 and DWC202503 in Healthy Adult Volunteers Daewoong Pharmaceutical Co. LTD. NA RECRUITING
(Jul 1, 2026)
PHASE1
A Study of Weekly Oral Dose of Ecnoglutide (VRB-101) for Weight Maintenance in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities Verdiva Bio Dev Limited NA ACTIVE NOT RECRUITING
(Jul 1, 2026)
PHASE2
Semaglutide Delivered Epi-Intradermally by Microarray Patch (VX-201) Versus Subcutaneous Administration in Healthy Overweight and Obese Participants Terrestrial Bio, Inc. NA RECRUITING
(Jul 1, 2026)
PHASE1
A Study to Assess the Efficacy, Safety and Tolerability of AT673 Co-administered With Semaglutide in Adult Participants With Type 2 Diabetes (T2D) and Overweight or Obesity Antag Therapeutics NA RECRUITING
(Jul 1, 2026)
PHASE2
Semaglutide for Low Back Pain Washington University School of Medicine NA NOT YET RECRUITING
(Jul 1, 2026)
PHASE2
Myocardial Metabolic Flux in Pulmonary Arterial Hypertension Imperial College London NA NOT YET RECRUITING
(Jul 1, 2026)
PHASE2
A Study of BGM0504 in Early T2DM With Obesity BrightGene Bio-Medical Technology Co., Ltd. NA RECRUITING
(Jul 1, 2026)
PHASE3
Evaluating the Efficacy and Safety of LUM-201 Plus Semaglutide Versus Semaglutide Plus Placebo in Older Obese Adults Lumos Pharma NA NOT YET RECRUITING
(Jul 1, 2026)
PHASE2
Randomized Double Blinded Placebo-Controlled w/Semaglutide to Prevent Weight Gain After Liver Transplant University of Virginia NA RECRUITING
(Jun 1, 2026)
PHASE2
A Study Comparing IBI362 vs Semaglutide in Chinese Adults With Early Type 2 Diabetes and Obesity Innovent Biologics (Suzhou) Co. Ltd. NA COMPLETED
(Jun 1, 2026)
PHASE3
A Research Study to See How Well New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Levels in People With Type 2 Diabetes (T2D), Compared to Daily Insulin Glargine (COMBINE 4) Novo Nordisk A/S NA COMPLETED
(Jun 1, 2026)
PHASE3
A Study of Orforglipron for the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities (ATTAIN-MAINTAIN) Eli Lilly and Company NA COMPLETED
(Jun 1, 2026)
PHASE3
Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Mellitus Who Are Not Achieving Glycemic Targets While Using GLP-1-Based Therapy Biomea Fusion Inc. NA RECRUITING
(Jun 1, 2026)
PHASE2
MIST (Metabolic Intervention With Semaglutide and THR-β Therapy) Trial Eccogene NA ACTIVE NOT RECRUITING
(Jun 1, 2026)
PHASE2
BALANCE-OBS: Bofanglutide (GZR18) Versus Semaglutide in Latin American Adults With Overweight or Obesity Carnot Laboratories NA NOT YET RECRUITING
(Jun 1, 2026)
PHASE3
BALANCE-DM2 Study of Bofanglutide in Adults With Type 2 Diabetes Carnot Laboratories NA NOT YET RECRUITING
(Jun 1, 2026)
PHASE3
A Research Study to Compare a Medicine Called Semaglutide Against Placebo in People With Peripheral Arterial Disease and Type 2 Diabetes Novo Nordisk A/S NA COMPLETED
(May 1, 2026)
PHASE3
A Research Study to See How Well the New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Level in People With Type 2 Diabetes Compared to Weekly Semaglutide (COMBINE 2) Novo Nordisk A/S NA COMPLETED
(May 1, 2026)
PHASE3
A Research Study to See How a New Weekly Insulin, Insulin Icodec When Given Along With Semaglutide Helps in Reducing the Blood Sugar Level in Patients With Type 2 Diabetes Novo Nordisk A/S NA COMPLETED
(May 1, 2026)
PHASE3
Trial of Semaglutide for Diabetic Kidney Disease in Type 1 Diabetes University of Washington NA RECRUITING
(May 1, 2026)
PHASE2
A Study on How CagriSema Affects Levels of Atorvastatin and Warfarin in the Blood of Participants With Excess Body Weight Novo Nordisk A/S NA COMPLETED
(May 1, 2026)
PHASE1
A Research Study to See How Well Different Doses of CagriSema Help People With Excess Body Weight Lose Weight Novo Nordisk A/S NA COMPLETED
(May 1, 2026)
PHASE3
A Study to Test Whether Survodutide Improves How the Body Uses Energy and Breaks Down Fat in People With Obesity Boehringer Ingelheim NA ACTIVE NOT RECRUITING
(May 1, 2026)
PHASE1
A Study Comparing IBI362 vs Semaglutide in Chinese Overweight or Obese Adults With Metabolic Dysfunction-associated Fatty Liver Disease (MAFLD) Innovent Biologics (Suzhou) Co. Ltd. NA ACTIVE NOT RECRUITING
(May 1, 2026)
PHASE3
UBT251 Injection Phase II (Type 2 Diabetes Mellitus) Study The United Bio-Technology (Hengqin) Co., Ltd. NA COMPLETED
(May 1, 2026)
PHASE2
GLP-1 Receptor Agonists to Decrease Ethanol and CVD Risk in HIV Vanderbilt University Medical Center NA RECRUITING
(May 1, 2026)
PHASE2
Effect of Semaglutide on Cannabis Use in Adults With Cannabis Use Disorder Anders Fink-Jensen, MD, DMSci NA RECRUITING
(May 1, 2026)
PHASE2
Understanding the Effect of CagriSema, Cagrilintide, and Semaglutide on Muscle Health (Role of Amylin Signature in Muscle Health) Novo Nordisk A/S NA RECRUITING
(May 1, 2026)
PHASE1
Effect of Semaglutide on Healing of Foot Ulcers in Type 2 Diabetes Patients Ole Lander Svendsen NA RECRUITING
(May 1, 2026)
PHASE3
A Research Study to Compare Blood Levels of Cagrilintide After Multiple Doses of Different Versions of Cagrilintide in Adults With Overweight or Obesity Novo Nordisk A/S NA NOT YET RECRUITING
(May 1, 2026)
PHASE1
A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus AstraZeneca NA RECRUITING
(May 1, 2026)
PHASE3
Effects of Semaglutide in HIV-Associated Lipohypertrophy Case Western Reserve University NA ACTIVE NOT RECRUITING
(Apr 1, 2026)
PHASE2
Research Study to Investigate How Well Semaglutide Tablets Taken Once Daily Work in People Who Are Overweight or Living With Obesity (OASIS 1) Novo Nordisk A/S NA COMPLETED
(Apr 1, 2026)
PHASE3
Semaglutide Effects in Obese Youth With Prediabetes/New Onset Type 2 Diabetes and Metabolic Dysfunction-Associated Steatotic Liver Disease Yale University NA ACTIVE NOT RECRUITING
(Apr 1, 2026)
PHASE2
A Research Study to Look Into How Semaglutide, Together With a Lower Dose of Insulin Glargine, Compares to a Higher Dose of Insulin Glargine Alone in People With Type 2 Diabetes (SUSTAIN OPTIMIZE) Novo Nordisk A/S NA COMPLETED
(Apr 1, 2026)
PHASE3
A Research Study to See How Semaglutide Helps People With Excess Weight, Lose Weight (STEP UP) Novo Nordisk A/S NA COMPLETED
(Apr 1, 2026)
PHASE3
A Research Study to See How Semaglutide Helps People With Excess Weight and Type 2 Diabetes Lose Weight Novo Nordisk A/S NA COMPLETED
(Apr 1, 2026)
PHASE3
Feasibility of Semaglutide in Advanced Lung Disease University of Pennsylvania NA RECRUITING
(Apr 1, 2026)
PHASE1, PHASE2
A Research Study to See How Well Semaglutide Helps People Who Have a Body Weight Above the Healthy Weight Range Novo Nordisk A/S NA COMPLETED
(Apr 1, 2026)
PHASE3
Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin With or Without SGLT2 Inhibitor (TRANSCEND-T2D-2) Eli Lilly and Company NA ACTIVE NOT RECRUITING
(Apr 1, 2026)
PHASE3
A Research Study Looking at How Well a Combination of the Medicines Semaglutide and NNC0480-0389 Works in People With Type 2 Diabetes Novo Nordisk A/S NA COMPLETED
(Mar 1, 2026)
PHASE2
Cardiac and Metabolic Effects of Semaglutide in Heart Failure With Preserved Ejection Fraction Mayo Clinic NA ENROLLING BY INVITATION
(Mar 1, 2026)
PHASE2
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Diet and Exercise Novo Nordisk A/S NA COMPLETED
(Mar 1, 2026)
PHASE3
AMAZE 8: A Research Study Investigating How Well the Medicine NNC0487-0111 Compared to Semaglutide Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight Novo Nordisk A/S NA NOT YET RECRUITING
(Mar 1, 2026)
PHASE3
A Research Study to Compare a New Medicine Oral Semaglutide to a Dummy Medicine in Children and Teenagers With Type 2 Diabetes Novo Nordisk A/S NA RECRUITING
(Sep, 2024)
PHASE3
A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Finland, as Part of Local Clinical Practice Novo Nordisk A/S NA COMPLETED
(Sep, 2024)
Research Study Looking at How Well Semaglutide Tablets Taken Once Daily Work in Chinese Adults Who Are Above a Healthy Weight Range (OASIS 3) Novo Nordisk A/S NA ACTIVE NOT RECRUITING
(Sep, 2024)
PHASE3
Semaglutide Treatment for Hyperglycaemia After Renal Transplantation Rigshospitalet, Denmark Aarhus University Hospital, Odense University Hospital RECRUITING
(Jun, 2024)
PHASE4
Semaglutide in CFRD University of Minnesota Cystic Fibrosis Foundation RECRUITING
(Jun, 2024)
PHASE2, PHASE3
A Study to Evaluate the Safety of Exposure to Wegovy During Pregnancy Novo Nordisk A/S NA ENROLLING BY INVITATION
(Oct, 2023)
A Research Study Looking Into Blood Levels of Semaglutide and NNC0480-0389 When Given in the Same Injection or in Two Separate Injections in Healthy People Novo Nordisk A/S NA COMPLETED
(Jun, 2023)
PHASE1
Efficacy and Long-term Safety of Oral Semaglutide Versus Sitagliptin in Subjects With Type 2 Diabetes Novo Nordisk A/S NA COMPLETED
(Jul, 2022)
PHASE3
Real-world Health Outcomes in Canadian Patients Using Semaglutide LMC Diabetes & Endocrinology Ltd. NA COMPLETED
(Feb, 2020)
A Trial Investigating the Effect of Semaglutide on Hypoglycaemic Counterregulation Compared to Placebo in Subjects With Type 2 Diabetes Novo Nordisk A/S NA COMPLETED
(Aug, 2018)
PHASE1


Semaglutide Generic API Manufacturers

Given below is the list of companies who have filed for Semaglutide generic, along with the locations of their manufacturing plants worldwide.


Semaglutide News

Affordable weight loss medication! Dr. Reddy's receives approval for generic oral semaglutide.

17 Apr, 2026

MSN Labs introduces semaglutide - The Hindu

17 Apr, 2026

Is a broad acceptance of semaglutide expected after the price drop?

16 Apr, 2026

Is a significant increase in semaglutide usage expected after the price drop? - BusinessToday

16 Apr, 2026

See More