Rifaximin Patent Expiration

Rifaximin is Used for treating travelers' diarrhea, reducing risk of hepatic encephalopathy episodes, and managing symptoms of irritable bowel syndrome with diarrhea. It was first introduced by Salix Pharmaceuticals Inc in its drug Xifaxan on May 25, 2004.


Rifaximin Patents

Given below is the list of patents protecting Rifaximin, along with the drug name that holds that patent and the company name owning that drug.

Drug Used in Drug Patent Number Drug Patent Title Drug Patent Expiry Drug Owner
Xifaxan US10314828 Methods of treating hepatic encephalopathy Jul 24, 2029 Salix Pharms
Xifaxan US10314828 Methods of treating hepatic encephalopathy Oct 02, 2029 Salix Pharms
Xifaxan US10335397 Methods of treating hepatic encephalopathy Jul 24, 2029 Salix Pharms
Xifaxan US10456384 Methods for treating irritable bowel syndrome (IBS) Feb 26, 2029 Salix Pharms
Xifaxan US10703763 Polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations Feb 27, 2026 Salix Pharms
Xifaxan US10709694 Methods of treating hepatic encephalopathy Jul 24, 2029 Salix Pharms
Xifaxan US10765667 Methods for treating irritable bowel syndrome (IBS) Feb 26, 2029 Salix Pharms
Xifaxan US11564912 Methods for treating irritable bowel syndrome (IBS) Feb 26, 2029 Salix Pharms
Xifaxan US11779571 Methods for treating irritable bowel syndrome (IBS) Feb 26, 2029 Salix Pharms
Xifaxan US6861053 Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth Aug 11, 2019

(Expired)

Salix Pharms
Xifaxan US7045620 Polymorphous forms of rifaximin, processes for their production and use thereof in medicinal preparations Jun 19, 2024

(Expired)

Salix Pharms
Xifaxan US7045620 Polymorphous forms of rifaximin, processes for their production and use thereof in medicinal preparations Jun 19, 2024

(Expired)

Salix Pharms
Xifaxan US7452857 Methods of treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth Aug 11, 2019

(Expired)

Salix Pharms
Xifaxan US7605240 Methods of treating diarrhea and bloating caused by small intestinal bacterial overgrowth Aug 11, 2019

(Expired)

Salix Pharms
Xifaxan US7612199 Polymorphic forms α, β, and γ of rifaximin Jun 19, 2024

(Expired)

Salix Pharms
Xifaxan US7612199 Polymorphic forms α, β, and γ of rifaximin Jun 19, 2024

(Expired)

Salix Pharms
Xifaxan US7718608 Methods of treating a subject suffering from irritable bowel syndrome Aug 11, 2019

(Expired)

Salix Pharms
Xifaxan US7902206 Polymorphic forms α, β and γ of rifaximin Jun 19, 2024

(Expired)

Salix Pharms
Xifaxan US7902206 Polymorphic forms α, β and γ of rifaximin Jun 19, 2024

(Expired)

Salix Pharms
Xifaxan US7906542 Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin Jun 01, 2025 Salix Pharms
Xifaxan US7906542 Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin Jun 01, 2025 Salix Pharms
Xifaxan US7915275 Use of polymorphic forms of rifaximin for medical preparations Feb 23, 2025 Salix Pharms
Xifaxan US7928115 Methods of treating travelers diarrhea and hepatic encephalopathy Jul 24, 2029 Salix Pharms
Xifaxan US7935799 Methods of treating diarrhea caused by small intestinal bacterial overgrowth Aug 11, 2019

(Expired)

Salix Pharms
Xifaxan US8158644 Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin Jun 19, 2024

(Expired)

Salix Pharms
Xifaxan US8158781 Polymorphic forms α, β and γ of rifaximin Jun 19, 2024

(Expired)

Salix Pharms
Xifaxan US8158781 Polymorphic forms α, β and γ of rifaximin Jun 19, 2024

(Expired)

Salix Pharms
Xifaxan US8193196 Polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations Sep 02, 2027 Salix Pharms
Xifaxan US8193196 Polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations Sep 02, 2027 Salix Pharms
Xifaxan US8309569 Methods for treating diarrhea-associated irritable bowel syndrome Jul 18, 2029 Salix Pharms
Xifaxan US8518949 Polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations Feb 27, 2026 Salix Pharms
Xifaxan US8642573 Methods of treating hepatic encephalopathy Oct 02, 2029 Salix Pharms
Xifaxan US8741904 Polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations Feb 27, 2026 Salix Pharms
Xifaxan US8829017 Methods of treating traveler's diarrhea and hepatic encephalopathy Jul 24, 2029 Salix Pharms
Xifaxan US8835452 Polymorphic forms α, β and γ of rifaximin Jun 19, 2024

(Expired)

Salix Pharms
Xifaxan US8853231 Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin Jun 19, 2024

(Expired)

Salix Pharms
Xifaxan US8946252 Methods of treating traveler's diarrhea and hepatic encephalopathy Jul 24, 2029 Salix Pharms
Xifaxan US8969398 Methods of treating hepatic encephalopathy Oct 02, 2029 Salix Pharms
Xifaxan US9271968 Polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations Feb 27, 2026 Salix Pharms
Xifaxan US9421195 Methods of treating hepatic encephalopathy Jul 24, 2029 Salix Pharms
Xifaxan US9629828 Methods of treating traveler's diarrhea and hepatic encephalopathy Jul 24, 2029 Salix Pharms


A patent's expiry date may change depending upon legal activities going on that patent. Critical activities like abandoning of a patent, term extension of a patent or amendment of its claims can increase or decrease the life of a patent hence affecting its expiry date and in turn affecting the generic launch date of that drug. Tracking these ongoing activities on a patent application helps to keep an eye on the latest developments in the patent process of the drug which can give an idea of how early a drug's generic could be available. The next section provides a list of recent legal activities on Rifaximin's patents.

Given below is the list recent legal activities going on the following patents of Rifaximin.

Event Date Patent/Publication
Patent litigations
Payment of Maintenance Fee, 12th Year, Large Entity 18 Apr, 2024 US8309569(Litigated)
Payment of Maintenance Fee, 4th Year, Large Entity 20 Feb, 2024 US10765667
Payment of Maintenance Fee, 8th Year, Large Entity 23 Jan, 2024 US9421195
Payment of Maintenance Fee, 4th Year, Large Entity 21 Dec, 2023 US10703763
Payment of Maintenance Fee, 4th Year, Large Entity 19 Dec, 2023 US10709694
Payment of Maintenance Fee, 12th Year, Large Entity 21 Nov, 2023 US8193196(Litigated)
Email Notification 11 Oct, 2023 US11779571
Mail Patent eGrant Notification 10 Oct, 2023 US11779571
Patent eGrant Notification 10 Oct, 2023 US11779571
Recordation of Patent eGrant 10 Oct, 2023 US11779571



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